Q6QNT2 (Q6QNT2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminoevulinate synthase 2 EMBL AAT09372.1

Gene names

Name:

ALAS2 EMBL AAT09372.1

Organism

Homo sapiens (Human) EMBL AAT09372.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	101 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	cellular iron ion homeostasis Inferred from electronic annotation. Source: Compara erythrocyte differentiation Inferred from electronic annotation. Source: Compara heme biosynthetic process Inferred from electronic annotation. Source: Compara hemoglobin biosynthetic process Inferred from electronic annotation. Source: Compara
Cellular_component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular_function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	101	1	EMBL AAT09372.1

Sequences

	Sequence		Length	Mass (Da)
	Q6QNT2 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 171408F0B6ACC864	FASTA	101	10,763
	10 20 30 40 50 60 MVTAAMLLQC CPVLARGPTS LLGKVVKTHQ FLFGIGRCPI LATQGPNCSQ IHLKATKAGG 70 80 90 100 DSPSWAKGHC PFMLSELQDG KSKIVQKAAP EVQEDVKAFK T

References

[1]

"Nucleotide variation at Msn and Alas2, two genes flanking the centromere of the X chromosome in humans." Nachman M.W., D'Agostino S.L., Tillquist C.R., Mobasher Z., Hammer M.F. Genetics 167:423-437(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: YCC10 EMBL AAT09397.1, YCC12 EMBL AAT09373.1, YCC13 EMBL AAT09382.1, YCC14 EMBL AAT09394.1, YCC16 EMBL AAT09395.1, YCC17 EMBL AAT09380.1, YCC2 EMBL AAT09376.1, YCC22 EMBL AAT09405.1, YCC23 EMBL AAT09400.1, YCC24 EMBL AAT09381.1, YCC25 EMBL AAT09388.1, YCC27 EMBL AAT09379.1, YCC32 EMBL AAT09408.1, YCC33 EMBL AAT09406.1, YCC38 EMBL AAT09403.1, YCC4 EMBL AAT09386.1, YCC40 EMBL AAT09407.1, YCC49 EMBL AAT09390.1, YCC51 EMBL AAT09396.1, YCC56 EMBL AAT09374.1, YCC57 EMBL AAT09387.1, YCC59 EMBL AAT09391.1, YCC6 EMBL AAT09411.1, YCC61 EMBL AAT09398.1, YCC62 EMBL AAT09399.1, YCC64 EMBL AAT09384.1, YCC65 EMBL AAT09410.1, YCC66 EMBL AAT09375.1, YCC67 EMBL AAT09371.1, YCC68 EMBL AAT09372.1, YCC69 EMBL AAT09401.1, YCC7 EMBL AAT09404.1, YCC71 EMBL AAT09383.1, YCC72 EMBL AAT09389.1, YCC76 EMBL AAT09393.1, YCC77 EMBL AAT09385.1, YCC78 EMBL AAT09377.1, YCC79 EMBL AAT09378.1, YCC8 EMBL AAT09409.1 and YCC9 EMBL AAT09402.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY532069 Genomic DNA. Translation: AAT09371.1. AY532070 Genomic DNA. Translation: AAT09372.1. AY532071 Genomic DNA. Translation: AAT09373.1. AY532072 Genomic DNA. Translation: AAT09374.1. AY532073 Genomic DNA. Translation: AAT09375.1. AY532074 Genomic DNA. Translation: AAT09376.1. AY532075 Genomic DNA. Translation: AAT09377.1. AY532076 Genomic DNA. Translation: AAT09378.1. AY532077 Genomic DNA. Translation: AAT09379.1. AY532078 Genomic DNA. Translation: AAT09380.1. AY532079 Genomic DNA. Translation: AAT09381.1. AY532080 Genomic DNA. Translation: AAT09382.1. AY532081 Genomic DNA. Translation: AAT09383.1. AY532082 Genomic DNA. Translation: AAT09384.1. AY532083 Genomic DNA. Translation: AAT09385.1. AY532084 Genomic DNA. Translation: AAT09386.1. AY532085 Genomic DNA. Translation: AAT09387.1. AY532086 Genomic DNA. Translation: AAT09388.1. AY532087 Genomic DNA. Translation: AAT09389.1. AY532088 Genomic DNA. Translation: AAT09390.1. AY532089 Genomic DNA. Translation: AAT09391.1. AY532091 Genomic DNA. Translation: AAT09393.1. AY532092 Genomic DNA. Translation: AAT09394.1. AY532093 Genomic DNA. Translation: AAT09395.1. AY532094 Genomic DNA. Translation: AAT09396.1. AY532095 Genomic DNA. Translation: AAT09397.1. AY532096 Genomic DNA. Translation: AAT09398.1. AY532097 Genomic DNA. Translation: AAT09399.1. AY532098 Genomic DNA. Translation: AAT09400.1. AY532099 Genomic DNA. Translation: AAT09401.1. AY532100 Genomic DNA. Translation: AAT09402.1. AY532101 Genomic DNA. Translation: AAT09403.1. AY532102 Genomic DNA. Translation: AAT09404.1. AY532103 Genomic DNA. Translation: AAT09405.1. AY532104 Genomic DNA. Translation: AAT09406.1. AY532105 Genomic DNA. Translation: AAT09407.1. AY532106 Genomic DNA. Translation: AAT09408.1. AY532107 Genomic DNA. Translation: AAT09409.1. AY532108 Genomic DNA. Translation: AAT09410.1. AY532109 Genomic DNA. Translation: AAT09411.1.
IPI	IPI00915312.
UniGene	Hs.522666. Hs.555936.
3D structure databases
ProteinModelPortal	Q6QNT2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6QNT2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q6QNT2.
Bgee	Q6QNT2.
Family and domain databases
InterPro	IPR015118. 5aminolev_synth_preseq. [Graphical view]
Pfam	PF09029. Preseq_ALAS. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ALAS2. human.

Entry information

Entry name

Q6QNT2_HUMAN

Accession

Primary (citable) accession number: Q6QNT2

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.