Q6QJ75 (XYN6_ASPNG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endo-1,4-beta-xylanase 6
Short name=Xylanase 6
EC=3.2.1.8

Alternative name(s):
1,4-beta-D-xylan xylanohydrolase 6

Gene names

Name:

XYN6

Organism

Aspergillus niger

Taxonomic identifier

5061 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose By similarity. Ref.1
Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted By similarity Ref.1.
Sequence similarities	Belongs to the glycosyl hydrolase 11 (cellulase G) family.
Biophysicochemical properties	pH dependence: Optimum pH is 3.5. Ref.1

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological_process	xylan catabolic process Inferred from direct assay. Source: UniProtKB
Cellular_component	extracellular region Inferred from direct assay. Source: UniProtKB
Molecular_function	endo-1,4-beta-xylanase activity Inferred from direct assay. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 16	16	Potential
	Chain	17 – 211	195	Endo-1,4-beta-xylanase 6		PRO_0000393173
Sites
	Active site	106	1	Nucleophile By similarity
	Active site	197	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6QJ75 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 973CD0651D5F8C9A	FASTA	211	22,561
	10 20 30 40 50 60 MKVTAAFAGL LVTALAAPAP EPVLVSRSAG INYVQNYNGN LGDFTYDESA GTFSMYWEDG 70 80 90 100 110 120 VSSDFVVGLG WTTGSSNPIT YSADYSASGS SSYLAVYGWD NYPQAEYYIV EDYGDYNPCS 130 140 150 160 170 180 SATSLGTVYS DGSTYQVCTD TRTNEPSITG TSTFTQYFSV RESTRTSGTV TVANHFNFWA 190 200 210 QHGFGNSDFN YQVVAVEAWS GAGSASVTIS S

References

[1]

"Efficient expression and secretion of two co-produced xylanases from Aspergillus niger in Pichia pastoris directed by their native signal peptides and the Saccharomyces cerevisiae a-mating factor." Korona B., Korona D., Bielecki S. Enzyme Microb. Technol. 39:683-689(2006) Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES. Strain: IBT-90.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY536638 mRNA. Translation: AAS46913.1.
3D structure databases
HSSP	HSSP built from PDB template 1AXK based on UniProtKB P23904.
ProteinModelPortal	Q6QJ75.
SMR	Q6QJ75. Positions 29-210.
ModBase	Search...
Protein-protein interaction databases
STRING	5061.CADANGAP00011453.
Protein family/group databases
CAZy	GH11. Glycoside Hydrolase Family 11.
mycoCLAP	XYN11F_ASPNG.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00114.
Family and domain databases
Gene3D	2.60.120.180. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR001137. Glyco_hydro_11. IPR013319. Glyco_hydro_11/12. IPR018208. Glyco_hydro_11_AS. [Graphical view]
Pfam	PF00457. Glyco_hydro_11. 1 hit. [Graphical view]
PRINTS	PR00911. GLHYDRLASE11.
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit.
PROSITE	PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit. PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYN6_ASPNG

Accession

Primary (citable) accession number: Q6QJ75

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 23, 2010
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program