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Unreviewed, UniProtKB/TrEMBL Q6QIQ5 (Q6QIQ5_HUMAN)

Last modified January 19, 2010. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    CD45 EMBL AAS46922.1
Gene names
Name: PTPRC EMBL AAS46922.1
OrganismHomo sapiens (Human) EMBL AAS46922.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length46 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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Ontologies

Gene Ontology (GO)
   Biological processT cell proliferation

Inferred from electronic annotation. Source: Compara

activation of MAPK activity

Inferred from electronic annotation. Source: Compara

heterotypic cell-cell adhesion

Inferred from electronic annotation. Source: Compara

leukocyte adhesion

Inferred from electronic annotation. Source: Compara

negative regulation of peptidyl-tyrosine phosphorylation

Inferred from electronic annotation. Source: Compara

negative regulation of protein amino acid autophosphorylation

Inferred from electronic annotation. Source: Compara

negative thymic T cell selection

Inferred from electronic annotation. Source: Compara

positive regulation of B cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of MAPKKK cascade

Inferred from electronic annotation. Source: Compara

positive regulation of T cell mediated cytotoxicity

Inferred from electronic annotation. Source: Compara

positive regulation of alpha-beta T cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of apoptosis

Inferred from electronic annotation. Source: Compara

positive regulation of gamma-delta T cell differentiation

Inferred from electronic annotation. Source: Compara

positive regulation of humoral immune response mediated by circulating immunoglobulin

Inferred from electronic annotation. Source: Compara

positive regulation of isotype switching to IgG isotypes

Inferred from electronic annotation. Source: Compara

positive thymic T cell selection

Inferred from electronic annotation. Source: Compara

regulation of B cell differentiation

Inferred from electronic annotation. Source: Compara

regulation of B cell receptor signaling pathway

Inferred from electronic annotation. Source: Compara

response to gamma radiation

Inferred from electronic annotation. Source: Compara

   Cellular componentexternal side of plasma membrane

Inferred from electronic annotation. Source: Compara

integral to plasma membrane

Inferred from electronic annotation. Source: Compara

   Molecular functionheparan sulfate proteoglycan binding

Inferred from electronic annotation. Source: Compara

heparin binding

Inferred from electronic annotation. Source: Compara

protein tyrosine phosphatase activity

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAS46922.1
Non-terminal residue461 EMBL AAS46922.1

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Sequences

Sequence LengthMass (Da)Tools
Q6QIQ5-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: A2FEABCA7124582C

FASTA464,550
        10         20         30         40 
VSSVQTPHLP THADSQTPSA GTDTQTFSGS AANAKLNPTP GSNAIS

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References

[1]"Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates."
Filip L.C., Mundy N.I.
Mol. Biol. Evol. 21:1504-1511(2004) [PubMed: 15014144] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY539667 Genomic DNA. Translation: AAS46922.1.
IPIIPI00943217.
UniGeneHs.654514

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ6QIQ5.

Genome annotation databases

EnsemblENST00000271610; ENSP00000271610; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000352140; ENSP00000193532; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000367366; ENSP00000356336; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000367367; ENSP00000356337; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000367376; ENSP00000356346; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000391970; ENSP00000375831; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000427110; ENSP00000406897; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000442510; ENSP00000411355; ENSG00000081237; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:9666. PTPRC.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ6QIQ5.

Gene expression databases

ArrayExpressQ6QIQ5.
BgeeQ6QIQ5.

Family and domain databases

ProtoNetSearch...

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Entry information

Entry nameQ6QIQ5_HUMAN
AccessionPrimary (citable) accession number: Q6QIQ5
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 19, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information