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Unreviewed, UniProtKB/TrEMBL Q6QIM3 (Q6QIM3_HUMAN)

Last modified January 19, 2010. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    CD45 EMBL AAS46954.1
Gene names
Name: PTPRC EMBL AAS46954.1
OrganismHomo sapiens (Human) EMBL AAS46954.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length69 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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Ontologies

Gene Ontology (GO)
   Biological processT cell proliferation

Inferred from electronic annotation. Source: Compara

activation of MAPK activity

Inferred from electronic annotation. Source: Compara

heterotypic cell-cell adhesion

Inferred from electronic annotation. Source: Compara

leukocyte adhesion

Inferred from electronic annotation. Source: Compara

negative regulation of peptidyl-tyrosine phosphorylation

Inferred from electronic annotation. Source: Compara

negative regulation of protein amino acid autophosphorylation

Inferred from electronic annotation. Source: Compara

negative thymic T cell selection

Inferred from electronic annotation. Source: Compara

positive regulation of B cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of MAPKKK cascade

Inferred from electronic annotation. Source: Compara

positive regulation of T cell mediated cytotoxicity

Inferred from electronic annotation. Source: Compara

positive regulation of alpha-beta T cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of apoptosis

Inferred from electronic annotation. Source: Compara

positive regulation of gamma-delta T cell differentiation

Inferred from electronic annotation. Source: Compara

positive regulation of humoral immune response mediated by circulating immunoglobulin

Inferred from electronic annotation. Source: Compara

positive regulation of isotype switching to IgG isotypes

Inferred from electronic annotation. Source: Compara

positive thymic T cell selection

Inferred from electronic annotation. Source: Compara

regulation of B cell differentiation

Inferred from electronic annotation. Source: Compara

regulation of B cell receptor signaling pathway

Inferred from electronic annotation. Source: Compara

response to gamma radiation

Inferred from electronic annotation. Source: Compara

   Cellular componentexternal side of plasma membrane

Inferred from electronic annotation. Source: Compara

integral to plasma membrane

Inferred from electronic annotation. Source: Compara

   Molecular functionheparan sulfate proteoglycan binding

Inferred from electronic annotation. Source: Compara

heparin binding

Inferred from electronic annotation. Source: Compara

protein tyrosine phosphatase activity

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAS46954.1
Non-terminal residue691 EMBL AAS46954.1

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Sequences

Sequence LengthMass (Da)Tools
Q6QIM3-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 446636A3A640A12F

FASTA698,155
        10         20         30         40         50         60 
PSQVWNMTVS MTSDNSMHVK CRPPRDRNGP HERYHLEVEA GNTLVRNESH KNCDFRVKDL 


QYSTDYTFK

« Hide

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References

[1]"Rapid evolution by positive Darwinian selection in the extracellular domain of the abundant lymphocyte protein CD45 in primates."
Filip L.C., Mundy N.I.
Mol. Biol. Evol. 21:1504-1511(2004) [PubMed: 15014144] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY539699 Genomic DNA. Translation: AAS46954.1.
IPIIPI00645319.
UniGeneHs.654514

3D structure databases

SMRQ6QIM3. Positions 1-69.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6QIM3.

Genome annotation databases

EnsemblENST00000271610; ENSP00000271610; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000348564; ENSP00000306782; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000352140; ENSP00000193532; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000367367; ENSP00000356337; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000367372; ENSP00000356342; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000367376; ENSP00000356346; ENSG00000081237; Homo sapiens. [Genome view]
ENST00000442510; ENSP00000411355; ENSG00000081237; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:9666. PTPRC.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ6QIM3.

Gene expression databases

ArrayExpressQ6QIM3.
BgeeQ6QIM3.

Family and domain databases

InterProIPR008957. Fibronectin_typ-III-like_fold.
IPR003961. FN_III.
[Graphical view]
PfamPF00041. fn3. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ6QIM3_HUMAN
AccessionPrimary (citable) accession number: Q6QIM3
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 19, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information