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Protein
Submitted name:

TNF receptor superfamily, member 1A

Gene

Tnfrsf1a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
TNF receptor superfamily, member 1AImported
Gene namesi
Name:Tnfrsf1aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1314884. Tnfrsf1a.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei207 – 22923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 440417Sequence analysisPRO_5004278659Add
BLAST

Proteomic databases

PaxDbiQ6QHF1.

Expressioni

Gene expression databases

BgeeiQ6QHF1.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000032491.

Structurei

3D structure databases

ProteinModelPortaliQ6QHF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 7539TNFR-CysInterPro annotationAdd
BLAST
Domaini77 – 11943TNFR-CysInterPro annotationAdd
BLAST
Domaini120 – 16041TNFR-CysInterPro annotationAdd
BLAST
Domaini350 – 43586DeathInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IXBX. Eukaryota.
ENOG4111YG2. LUCA.
HOVERGENiHBG058842.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR020419. TNFR_1A.
[Graphical view]
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 3 hits.
[Graphical view]
PRINTSiPR01918. TNFACTORR1A.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 4 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS00652. TNFR_NGFR_1. 3 hits.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6QHF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PGLLLSLVLL ALLMGIHPSG VTGLVPSLGD REKRDSLCPQ GKYVHSKNNS
60 70 80 90 100
ICCTKCHKGT YLVSDCPSPG RDTVCRECEK GTFTASQNYL RQCLSCKTCR
110 120 130 140 150
KEMSQVEISP CQADKDTVCG CKENQFQRYL SETHFQCVDC SPCFNGTVTI
160 170 180 190 200
PCKETQNTVC NCHAGFFLRE SECVPCSHCK KNEECMKLCL PPPLANVTNP
210 220 230 240 250
QDSGTAVLLP LVILLGLCLL SFIFISLMCR YPRWRPEVYS IICRDPVPVK
260 270 280 290 300
EEKAGKPLTP APSPAFSPTS GFNPTLGFST PGFSSPVSST PISPIFGPSN
310 320 330 340 350
WHFMPPVSEV VPTQGADPLL YESLCSVPAP TSVQKWEDSA HPQRPDNADL
360 370 380 390 400
AILYAVVDGV PPARWKEFMR FMGLSEHEIE RLEMQNGRCL REAQYSMLEA
410 420 430 440
WRRRTPRHED TLEVVGLVLS KMNLAGCLEN ILEALRNPAP
Length:440
Mass (Da):48,632
Last modified:July 5, 2004 - v1
Checksum:i580A2D2E334612A3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei440 – 4401Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY541589 mRNA. Translation: AAS48428.1.
UniGeneiMm.1258.
Mm.474976.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY541589 mRNA. Translation: AAS48428.1.
UniGeneiMm.1258.
Mm.474976.

3D structure databases

ProteinModelPortaliQ6QHF1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000032491.

Proteomic databases

PaxDbiQ6QHF1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1314884. Tnfrsf1a.

Phylogenomic databases

eggNOGiENOG410IXBX. Eukaryota.
ENOG4111YG2. LUCA.
HOVERGENiHBG058842.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiQ6QHF1.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR020419. TNFR_1A.
[Graphical view]
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 3 hits.
[Graphical view]
PRINTSiPR01918. TNFACTORR1A.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 4 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS00652. TNFR_NGFR_1. 3 hits.
PS50050. TNFR_NGFR_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequencing of the tnfrsf1a gene in SPRET/Ei, C57BL/6JIco and DBA/2CrlBr."
    Staelens J., Wielockx B., Puimege L., Vandenabeele A., Libert C.
    Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DBA/2CrlBrImported.
    Tissue: LiverImported.

Entry informationi

Entry nameiQ6QHF1_MOUSE
AccessioniPrimary (citable) accession number: Q6QHF1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 17, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.