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Protein

Tripartite motif-containing protein 44

Gene

Trim44

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17 (By similarity). Is a negative regulator of PAX6 expression (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri174 – 215B box-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Tripartite motif-containing protein 44
Alternative name(s):
Protein DIPB
Gene namesi
Name:Trim44
Synonyms:Dipb
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1304877 Trim44

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002203741 – 344Tripartite motif-containing protein 44Add BLAST344

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei336PhosphoserineBy similarity1
Modified residuei339PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ6QA27

Interactioni

Subunit structurei

Interacts (via coiled coil) with TRIM17 (via coiled coil).By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007018

Structurei

3D structure databases

ProteinModelPortaliQ6QA27
SMRiQ6QA27
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili290 – 325Sequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi79 – 172Glu-richAdd BLAST94

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri174 – 215B box-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGiENOG410IPQC Eukaryota
ENOG4111H1M LUCA
HOGENOMiHOG000134694
HOVERGENiHBG057191
InParanoidiQ6QA27
KOiK12020
PhylomeDBiQ6QA27
TreeFamiTF333911

Family and domain databases

CDDicd00021 BBOX, 1 hit
InterProiView protein in InterPro
IPR000315 Znf_B-box
PfamiView protein in Pfam
PF00643 zf-B_box, 1 hit
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
PROSITEiView protein in PROSITE
PS50119 ZF_BBOX, 1 hit

Sequencei

Sequence statusi: Complete.

Q6QA27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGVGAACE ELPPDGTCDE CEPDEAPGAE EVCRDCGFCY CRRHADAHRQ
60 70 80 90 100
KFLSHRLAAY VHGAQAWTPP ASGDDALPED VEAKGEAEGE VESEVGEEES
110 120 130 140 150
ESEVDSESEE ESETEEDSED ESDEESEEDS EEEMEDEQES EAEEDNQEGE
160 170 180 190 200
SEAEGETEAE SEFDPEIEME AERVAKRKCP DHGLDLSTYC QEDRQLICVL
210 220 230 240 250
CPVIGAHRGH QLSTLDEAFE ELRSKDSGGL KAAMIELVER LKFKSSDPKV
260 270 280 290 300
TRDQMKVFIQ QEFKKVQKVI ADEEQKALHL VDIQEAMATA HVTEILADIQ
310 320 330 340
SHMDRLMTQM AQAKEQLDTS NESAEPKAEG DEEGPSGASE EEDT
Length:344
Mass (Da):38,086
Last modified:July 5, 2004 - v1
Checksum:iFAC0A10A08800EF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY551091 mRNA Translation: AAS58454.1
RefSeqiNP_001013221.1, NM_001013203.1
UniGeneiRn.229767

Genome annotation databases

GeneIDi362172
KEGGirno:362172
UCSCiRGD:1304877 rat

Similar proteinsi

Entry informationi

Entry nameiTRI44_RAT
AccessioniPrimary (citable) accession number: Q6QA27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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