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Protein

Transposon Ty4-H Gag polyprotein

Gene

TY4A-H

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.By similarity

GO - Molecular functioni

  • RNA binding Source: SGD
  • zinc ion binding Source: InterPro

GO - Biological processi

  • transposition, RNA-mediated Source: SGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Transposon Ty4-H Gag polyprotein
Short name:
TY4A
Short name:
Transposon Ty4 protein A
Gene namesi
Name:TY4A-H
Synonyms:YHLWTy4-1 GAG
Ordered Locus Names:YHL009W-A
ORF Names:YHL008W-B
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome VIII

Organism-specific databases

CYGDiYHL009w-a.
SGDiS000007371. YHL009W-A.

Subcellular locationi

GO - Cellular componenti

  • retrotransposon nucleocapsid Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 413413Transposon Ty4-H Gag polyproteinPRO_0000279381Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi36416. 15 interactions.
MINTiMINT-504056.

Structurei

3D structure databases

ProteinModelPortaliQ6Q5P6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili39 – 11577Sequence AnalysisAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG283194.
GeneTreeiENSGT00720000109470.
HOGENOMiHOG000155564.
InParanoidiQ6Q5P6.
OrthoDBiEOG7G1VGM.

Family and domain databases

InterProiIPR001878. Znf_CCHC.
[Graphical view]
SMARTiSM00343. ZnF_C2HC. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Note: The Gag-Pol polyprotein is generated by a +1 ribosomal frameshift.

Isoform Transposon Ty4-H Gag polyprotein (identifier: Q6Q5P6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MATPVRDETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVKQ
60 70 80 90 100
YQRNLNRFKT ILNGLKAEEE KLSETDDIQM LAEKLLKLGE TIDKVENRIV
110 120 130 140 150
DLVEKIQLLE TNENNNILHE HIDATGTYYL FDTLTSTNKR FYPKDCVFDY
160 170 180 190 200
RTNNVENIPI LLNNFKKFIK KYQFDDVFEN DIIEIDPREN EILCKIIKEG
210 220 230 240 250
LGESLDIMNT NTTDIFRIID GLKNKYRSLH GRDVRIRAWE KVLVDTTCRN
260 270 280 290 300
SALLMNKLQK LVLMEKWIFS KCCQDCPNLK DYLQEAIMGT LHESLRNSVK
310 320 330 340 350
QRLYNIPHNV GINHEEFLIN TVIETVIDLS PIADDQIENS CMYCKSVFHC
360 370 380 390 400
SINCKKKPNR ELRPDSTNFS KTYYLQGAQR QQQLKSSAKR TKVLEQDTKK
410
VKQSVQQQKT GNY
Note: Produced by conventional translation.
Length:413
Mass (Da):48,214
Last modified:July 5, 2004 - v1
Checksum:iFB55118BEC987195
GO
Isoform Transposon Ty4-H Gag-Pol polyprotein (identifier: P0C2J7-1) [UniParc]FASTAAdd to basket

The sequence of this isoform can be found in the external entry P0C2J7.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by +1 ribosomal frameshifting between codon Leu-362 and Gly-363 of the YHL009W-A ORF.
Length:1,802
Mass (Da):207,970
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11581 Genomic DNA. No translation available.
AY557839 Genomic DNA. Translation: AAS56165.1.
BK006934 Genomic DNA. Translation: DAA06679.1.
PIRiS52610.
RefSeqiNP_058134.1. NM_001184403.1. [Q6Q5P6-1]

Genome annotation databases

EnsemblFungiiYHL009W-A; YHL009W-A; YHL009W-A. [Q6Q5P6-1]
GeneIDi856379.
KEGGisce:YHL009W-A.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U11581 Genomic DNA. No translation available.
AY557839 Genomic DNA. Translation: AAS56165.1.
BK006934 Genomic DNA. Translation: DAA06679.1.
PIRiS52610.
RefSeqiNP_058134.1. NM_001184403.1. [Q6Q5P6-1]

3D structure databases

ProteinModelPortaliQ6Q5P6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36416. 15 interactions.
MINTiMINT-504056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYHL009W-A; YHL009W-A; YHL009W-A. [Q6Q5P6-1]
GeneIDi856379.
KEGGisce:YHL009W-A.

Organism-specific databases

CYGDiYHL009w-a.
SGDiS000007371. YHL009W-A.

Phylogenomic databases

eggNOGiNOG283194.
GeneTreeiENSGT00720000109470.
HOGENOMiHOG000155564.
InParanoidiQ6Q5P6.
OrthoDBiEOG7G1VGM.

Miscellaneous databases

NextBioi981872.

Family and domain databases

InterProiIPR001878. Znf_CCHC.
[Graphical view]
SMARTiSM00343. ZnF_C2HC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence."
    Kim J.M., Vanguri S., Boeke J.D., Gabriel A., Voytas D.F.
    Genome Res. 8:464-478(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE.
  5. "Happy together: the life and times of Ty retrotransposons and their hosts."
    Lesage P., Todeschini A.L.
    Cytogenet. Genome Res. 110:70-90(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVIEW.

Entry informationi

Entry nameiYH41A_YEAST
AccessioniPrimary (citable) accession number: Q6Q5P6
Secondary accession number(s): D3DKQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: July 5, 2004
Last modified: July 22, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Retrotransposons are mobile genetic entities that are able to replicate via an RNA intermediate and a reverse transcription step. In contrast to retroviruses, retrotransposons are non-infectious, lack an envelope and remain intracellular. Ty4 retrotransposons belong to the copia elements (pseudoviridae).

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VIII
    Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.