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Q6Q5P6

- YH41A_YEAST

UniProt

Q6Q5P6 - YH41A_YEAST

Protein

Transposon Ty4-H Gag polyprotein

Gene

TY4A-H

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.By similarity

    GO - Molecular functioni

    1. RNA binding Source: SGD
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. transposition, RNA-mediated Source: SGD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transposon Ty4-H Gag polyprotein
    Short name:
    TY4A
    Short name:
    Transposon Ty4 protein A
    Gene namesi
    Name:TY4A-H
    Synonyms:YHLWTy4-1 GAG
    Ordered Locus Names:YHL009W-A
    ORF Names:YHL008W-B
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VIII

    Organism-specific databases

    CYGDiYHL009w-a.
    SGDiS000007371. YHL009W-A.

    Subcellular locationi

    GO - Cellular componenti

    1. retrotransposon nucleocapsid Source: SGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 413413Transposon Ty4-H Gag polyproteinPRO_0000279381Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriQ6Q5P6.

    Interactioni

    Protein-protein interaction databases

    BioGridi36416. 15 interactions.
    MINTiMINT-504056.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6Q5P6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili39 – 11577Sequence AnalysisAdd
    BLAST

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG283194.
    GeneTreeiENSGT00720000109470.
    HOGENOMiHOG000155564.
    OrthoDBiEOG7G1VGM.

    Family and domain databases

    InterProiIPR001878. Znf_CCHC.
    [Graphical view]
    SMARTiSM00343. ZnF_C2HC. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by ribosomal frameshifting. Align

    Note: The Gag-Pol polyprotein is generated by a +1 ribosomal frameshift.

    Isoform Transposon Ty4-H Gag polyprotein (identifier: Q6Q5P6-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MATPVRDETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVKQ    50
    YQRNLNRFKT ILNGLKAEEE KLSETDDIQM LAEKLLKLGE TIDKVENRIV 100
    DLVEKIQLLE TNENNNILHE HIDATGTYYL FDTLTSTNKR FYPKDCVFDY 150
    RTNNVENIPI LLNNFKKFIK KYQFDDVFEN DIIEIDPREN EILCKIIKEG 200
    LGESLDIMNT NTTDIFRIID GLKNKYRSLH GRDVRIRAWE KVLVDTTCRN 250
    SALLMNKLQK LVLMEKWIFS KCCQDCPNLK DYLQEAIMGT LHESLRNSVK 300
    QRLYNIPHNV GINHEEFLIN TVIETVIDLS PIADDQIENS CMYCKSVFHC 350
    SINCKKKPNR ELRPDSTNFS KTYYLQGAQR QQQLKSSAKR TKVLEQDTKK 400
    VKQSVQQQKT GNY 413

    Note: Produced by conventional translation.

    Length:413
    Mass (Da):48,214
    Last modified:July 5, 2004 - v1
    Checksum:iFB55118BEC987195
    GO
    Isoform Transposon Ty4-H Gag-Pol polyprotein (identifier: P0C2J7-1) [UniParc]FASTAAdd to Basket

    The sequence of this isoform can be found in the external entry P0C2J7.
    Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

    Note: Produced by +1 ribosomal frameshifting between codon Leu-362 and Gly-363 of the YHL009W-A ORF.

    Length:1,802
    Mass (Da):207,970
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U11581 Genomic DNA. No translation available.
    AY557839 Genomic DNA. Translation: AAS56165.1.
    BK006934 Genomic DNA. Translation: DAA06679.1.
    PIRiS52610.
    RefSeqiNP_058134.1. NM_001184403.1. [Q6Q5P6-1]

    Genome annotation databases

    EnsemblFungiiYHL009W-A; YHL009W-A; YHL009W-A. [Q6Q5P6-1]
    GeneIDi856379.
    KEGGisce:YHL009W-A.

    Keywords - Coding sequence diversityi

    Ribosomal frameshifting

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U11581 Genomic DNA. No translation available.
    AY557839 Genomic DNA. Translation: AAS56165.1 .
    BK006934 Genomic DNA. Translation: DAA06679.1 .
    PIRi S52610.
    RefSeqi NP_058134.1. NM_001184403.1. [Q6Q5P6-1 ]

    3D structure databases

    ProteinModelPortali Q6Q5P6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 36416. 15 interactions.
    MINTi MINT-504056.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YHL009W-A ; YHL009W-A ; YHL009W-A . [Q6Q5P6-1 ]
    GeneIDi 856379.
    KEGGi sce:YHL009W-A.

    Organism-specific databases

    CYGDi YHL009w-a.
    SGDi S000007371. YHL009W-A.

    Phylogenomic databases

    eggNOGi NOG283194.
    GeneTreei ENSGT00720000109470.
    HOGENOMi HOG000155564.
    OrthoDBi EOG7G1VGM.

    Miscellaneous databases

    NextBioi 981872.

    Gene expression databases

    Genevestigatori Q6Q5P6.

    Family and domain databases

    InterProi IPR001878. Znf_CCHC.
    [Graphical view ]
    SMARTi SM00343. ZnF_C2HC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence."
      Kim J.M., Vanguri S., Boeke J.D., Gabriel A., Voytas D.F.
      Genome Res. 8:464-478(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NOMENCLATURE.
    5. "Happy together: the life and times of Ty retrotransposons and their hosts."
      Lesage P., Todeschini A.L.
      Cytogenet. Genome Res. 110:70-90(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: REVIEW.

    Entry informationi

    Entry nameiYH41A_YEAST
    AccessioniPrimary (citable) accession number: Q6Q5P6
    Secondary accession number(s): D3DKQ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 6, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Retrotransposons are mobile genetic entities that are able to replicate via an RNA intermediate and a reverse transcription step. In contrast to retroviruses, retrotransposons are non-infectious, lack an envelope and remain intracellular. Ty4 retrotransposons belong to the copia elements (pseudoviridae).

    Keywords - Technical termi

    Complete proteome, Reference proteome, Transposable element

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome VIII
      Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

    External Data

    Dasty 3