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Protein
Submitted name:

Ribosomal protein S15a

Gene

rps15a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • brain development Source: ZFIN
  • chordate embryonic development Source: ZFIN
  • regulation of cell cycle Source: ZFIN
  • translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal proteinUniRule annotationImported

Enzyme and pathway databases

ReactomeiR-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-6791226. Major pathway of rRNA processing in the nucleolus.
R-DRE-72649. Translation initiation complex formation.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DRE-72702. Ribosomal scanning and start codon recognition.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Submitted name:
Ribosomal protein S15aImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:rps15aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 3

Organism-specific databases

ZFINiZDB-GENE-030131-8708. rps15a.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000108197.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S8P family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1754. Eukaryota.
COG0096. LUCA.
GeneTreeiENSGT00390000003021.
HOGENOMiHOG000204097.
HOVERGENiHBG056618.
KOiK02957.
OMAiTHEVTPA.
OrthoDBiEOG77Q4ZM.
TreeFamiTF300067.

Family and domain databases

HAMAPiMF_01302_A. Ribosomal_S8_A.
InterProiIPR000630. Ribosomal_S8.
[Graphical view]
PANTHERiPTHR11758. PTHR11758. 1 hit.
PfamiPF00410. Ribosomal_S8. 1 hit.
[Graphical view]
SUPFAMiSSF56047. SSF56047. 1 hit.
PROSITEiPS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6Q420-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRMNVLADA LKSINNAEKR GKRQVLLRPC SKVIVRFLTV MMKHGYIGEF
60 70 80 90 100
EIIDDHRAGK IVVNLTGRLN KCGVISPRFD VQLKDLEKWQ NNLLPSRQFG
110 120 130
FIVLTTSAGI MDHEEARRKH TGGKILGFFF
Length:130
Mass (Da):14,840
Last modified:July 5, 2004 - v1
Checksum:iD4E90AD921F3E083
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR450821 Genomic DNA. No translation available.
BC107523 mRNA. Translation: AAI07524.1.
AY561512 mRNA. Translation: AAS66965.1.
RefSeqiNP_997927.1. NM_212762.1.
UniGeneiDr.1428.

Genome annotation databases

EnsembliENSDART00000128613; ENSDARP00000108197; ENSDARG00000010160.
ENSDART00000172555; ENSDARP00000134460; ENSDARG00000010160.
GeneIDi336764.
KEGGidre:336764.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR450821 Genomic DNA. No translation available.
BC107523 mRNA. Translation: AAI07524.1.
AY561512 mRNA. Translation: AAS66965.1.
RefSeqiNP_997927.1. NM_212762.1.
UniGeneiDr.1428.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000108197.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000128613; ENSDARP00000108197; ENSDARG00000010160.
ENSDART00000172555; ENSDARP00000134460; ENSDARG00000010160.
GeneIDi336764.
KEGGidre:336764.

Organism-specific databases

CTDi6210.
ZFINiZDB-GENE-030131-8708. rps15a.

Phylogenomic databases

eggNOGiKOG1754. Eukaryota.
COG0096. LUCA.
GeneTreeiENSGT00390000003021.
HOGENOMiHOG000204097.
HOVERGENiHBG056618.
KOiK02957.
OMAiTHEVTPA.
OrthoDBiEOG77Q4ZM.
TreeFamiTF300067.

Enzyme and pathway databases

ReactomeiR-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-6791226. Major pathway of rRNA processing in the nucleolus.
R-DRE-72649. Translation initiation complex formation.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DRE-72702. Ribosomal scanning and start codon recognition.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Family and domain databases

HAMAPiMF_01302_A. Ribosomal_S8_A.
InterProiIPR000630. Ribosomal_S8.
[Graphical view]
PANTHERiPTHR11758. PTHR11758. 1 hit.
PfamiPF00410. Ribosomal_S8. 1 hit.
[Graphical view]
SUPFAMiSSF56047. SSF56047. 1 hit.
PROSITEiPS00053. RIBOSOMAL_S8. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Many ribosomal protein genes are cancer genes in zebrafish."
    Amsterdam A., Sadler K.C., Lai K., Farrington S., Bronson R.T., Lees J.A., Hopkins N.
    PLoS Biol. 2:690-698(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LiverImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  4. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  5. Ensembl
    Submitted (NOV-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ6Q420_DANRE
AccessioniPrimary (citable) accession number: Q6Q420
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.