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Protein
Submitted name:

Endoglin

Gene

Eng

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
EndoglinImported
Gene namesi
Name:EngImported
ORF Names:rCG_45763Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1593188 Eng

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei579 – 606HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_501353344326 – 650Sequence analysisAdd BLAST625

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini360 – 510ZPInterPro annotationAdd BLAST151

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG005573
KOiK06526

Family and domain databases

InterProiView protein in InterPro
IPR001507 ZP_dom
PfamiView protein in Pfam
PF00100 Zona_pellucida, 1 hit

Sequencei

Sequence statusi: Complete.

Q6Q3E8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRSMLPLVI TLLLVIYSFV PTSLAERVGC DLQRVDSTRG EVTYTTSQVS
60 70 80 90 100
EGCVAQVANA AHEVHVLFLN LSRRKSEVEL TLQASKQNGT ETREVFLVFI
110 120 130 140 150
SNENVLVKLQ APEIPLHLVY NSSLEVFKGP KVNSTPLPSF TSKTQILDWA
160 170 180 190 200
ATKGTITSIA ALDDPKSIVL RLGQDPKAPP FCFPEAQKDM GVTLEWQPRT
210 220 230 240 250
QTPVQGCHLE GVTGHKEAYV LRIRSGSEAG PRTVTVTVKL SCTSGDAVLI
260 270 280 290 300
LQGPPYVSWL IDTNHNMQIW TTGEYSIKIF PENNIKGFEL PDTPQGLIGE
310 320 330 340 350
ARKLNASIVT FVEIPLTSDV SLTVSSCGGG LQTSPAPVVT TPPKDTCSPE
360 370 380 390 400
LLMSLIQPKC GNDVMTLALN KKLVQTLQCT ITGLAFWDSS CQAKDQDGHL
410 420 430 440 450
VLSSTYSSCG MKVTDHVISN EVIINLPSGL PPLRKKVQCI DMDSLSFQLG
460 470 480 490 500
LYLSPHFLQA SNTIELGQQG FVQVSMSPLT SEVTVQLDSC HLDLGPEGDM
510 520 530 540 550
VELIQSRAAK GSCVSLLSPS PEGDPRFSFL LRVYMVPTPA AGTLSCNLAL
560 570 580 590 600
HPSTLSQEVY KTVSMRLNIV SPDLSGKGLV LPSVLGITFG AFLIGALLTA
610 620 630 640 650
ALWYIYSHTR APSKREPVVA VAAPASSESS STNHSIGSTQ STPCSTSSMA
Length:650
Mass (Da):69,944
Last modified:July 5, 2004 - v1
Checksum:i3E7DBC6A178E1E4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY562420 mRNA Translation: AAS67893.1
CH474001 Genomic DNA Translation: EDL93221.1
RefSeqiNP_001010968.1, NM_001010968.2
UniGeneiRn.187025

Genome annotation databases

GeneIDi497010
KEGGirno:497010

Similar proteinsi

Entry informationi

Entry nameiQ6Q3E8_RAT
AccessioniPrimary (citable) accession number: Q6Q3E8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health