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Q6PZE0 (MUC19_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mucin-19

Short name=MUC-19
Alternative name(s):
Gel-forming secreted mucin-19
Sublingual apomucin
Gene names
Name:Muc19
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length7524 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May function in ocular mucus homeostasis By similarity.

Subcellular location

Secreted Potential.

Tissue specificity

Specifically expressed in sublingual salivary glands. Expressed by mucous cells of the submandibular gland and submucosal gland of the trachea. Expression is altered in sld (sublingual gland differentiation arrest) mutants. Ref.1 Ref.2 Ref.3

Sequence similarities

Contains 1 CTCK (C-terminal cystine knot-like) domain.

Contains 1 TIL (trypsin inhibitory-like) domain.

Contains 2 VWFC domains.

Contains 3 VWFD domains.

Sequence caution

The sequence AAO49800.1 differs from that shown. Reason: Contaminating sequence. Sequence of unknown origin in the N-terminal part.

Alternative products

This entry describes 6 isoforms produced by alternative splicing. [Align] [Select]

Note: Isoform 1 and isoform 2-6 share the first 17 amino acid residues that correspond to the signal sequence.
Isoform 1 (identifier: Q6PZE0-1)

Also known as: Mucin-19;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q6JHY2-1)

Also known as: Smgc;

The sequence of this isoform can be found in the external entry Q6JHY2.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoform 3 (identifier: Q6JHY2-2)

The sequence of this isoform can be found in the external entry Q6JHY2.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: No experimental confirmation available.
Isoform 4 (identifier: Q6JHY2-3)

The sequence of this isoform can be found in the external entry Q6JHY2.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: No experimental confirmation available.
Isoform 5 (identifier: Q6JHY2-4)

Also known as: t-Smgc;

The sequence of this isoform can be found in the external entry Q6JHY2.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Isoform 6 (identifier: Q6JHY2-5)

The sequence of this isoform can be found in the external entry Q6JHY2.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 75247504Mucin-19
PRO_5000093121

Regions

Domain56 – 257202VWFD 1
Domain298 – 35356TIL
Domain392 – 600209VWFD 2
Domain852 – 1062211VWFD 3
Repeat1321 – 14831631
Repeat1484 – 16461632
Repeat1647 – 18091633
Repeat1810 – 19721634
Repeat1973 – 21351635
Repeat2136 – 22981636
Repeat2299 – 24611637
Repeat2462 – 26241638
Repeat2625 – 27871639
Repeat2788 – 295016310
Repeat2951 – 311316311
Repeat3114 – 327616312
Repeat3277 – 343916313
Repeat3440 – 360216314
Repeat3603 – 376516315
Repeat3766 – 392816316
Repeat3929 – 409116317
Repeat4092 – 425416318
Repeat4255 – 441716319
Repeat4418 – 458016320
Repeat4581 – 474316321
Repeat4744 – 490616322
Repeat4907 – 506916323
Repeat5070 – 523216324
Repeat5233 – 539516325
Repeat5396 – 555816326
Repeat5559 – 572116327
Repeat5722 – 588416328
Repeat5885 – 604716329
Repeat6048 – 621016330
Repeat6211 – 637316331
Repeat6374 – 653616332
Repeat6537 – 669916333
Repeat6700 – 686216334
Repeat6863 – 702516335
Repeat7026 – 718816336
Domain7302 – 736867VWFC 1
Domain7370 – 743263VWFC 2
Domain7435 – 751985CTCK
Region1321 – 71885868Approximate repeats
Compositional bias1216 – 72856070Thr-rich
Compositional bias1238 – 72496012Ser-rich

Amino acid modifications

Disulfide bond79 ↔ 87 By similarity
Disulfide bond7435 ↔ 7482 By similarity
Disulfide bond7449 ↔ 7496 By similarity
Disulfide bond7458 ↔ 7512 By similarity
Disulfide bond7462 ↔ 7514 By similarity
Disulfide bond? ↔ 7518 By similarity

Experimental info

Sequence conflict71111V → A in AAO49800. Ref.3
Sequence conflict71781P → L in AAO38851. Ref.2
Sequence conflict71781P → L in AAO49800. Ref.3
Sequence conflict72931E → V in AAO38851. Ref.2
Sequence conflict72931E → V in AAO49800. Ref.3
Sequence conflict72931E → V in AAH61502. Ref.4
Sequence conflict73331V → L in AAO38851. Ref.2
Sequence conflict73331V → L in AAH61502. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 (Mucin-19) [UniParc].

Last modified October 25, 2004. Version 2.
Checksum: B99A4519CE1EF6D4

FASTA7,524693,499
        10         20         30         40         50         60 
MKLILLYLAV VLCFVGKGAA RSPTTTRTPT PSTSEKASHV PEATPTYSEA NEVAGEATMW 

        70         80         90        100        110        120 
GKDKYKALNG HIFSFESECT FTFCRDCAEP GGDFNIEIKK HKNGDIEEIK ALIDDVEILV 

       130        140        150        160        170        180 
VRNSISVNEE RVKVPFSNKM IHIKKQGNHY SLKTRRRILS LKWSKDKLSL ILYSHYTTCG 

       190        200        210        220        230        240 
LCGNFDSVPG DDVNEHIASS KISNDCPSPL SRSNEVCEDG VQYCDKIIET YFEKCSKVSP 

       250        260        270        280        290        300 
LSREYKNVCA DEYCRKGGGK QTTCDTYSEL ARLCAYDGPG DYEHWRDDSA VVCAKEQCPG 

       310        320        330        340        350        360 
KHIYKECGPS NPPTCSNVAP FQDSECVSGC TCPEGYLLDD IGEKGKCVLK EKCPCESNGK 

       370        380        390        400        410        420 
VYKPGKVREG PCGSRCTCQE AKWSCTEARC PGICKVEGSS FTTFDDNKFS HPGDCHFLAV 

       430        440        450        460        470        480 
HNDEISISVE IHPCGNGQTG SCLTSVMVLQ NSSSSSNRYV FNRDGTVTKD GVIIKGYYYS 

       490        500        510        520        530        540 
DDVQIFNSSS SYMQAEILSH IKLQIQLAPR MQLYVSLAPN TSTDTVGLCG SFNNKAEDDF 

       550        560        570        580        590        600 
MSSQNILEST AQAFANSWEM MPCSEGSPSS CVSIETEKFA ESNCEILLSS SGPFAACHQT 

       610        620        630        640        650        660 
VNPKFYHEEC KKYTCSCENG QDCLCTVLGN YVKACAEKEI YLVGWRDGLC EVSCPSGLVF 

       670        680        690        700        710        720 
NYKVKTCNSS CRSLSARDRS CDIEDIPVDG CTCPDGMYQN NEGNCVQKSE CDCYVNDEIV 

       730        740        750        760        770        780 
QPGKSILIDD NKCVCQDGVL HCQTPLDLTL QNCSRGAEYI DCKDPKAQRR TERTCATRNI 

       790        800        810        820        830        840 
PDFEGDLPCK RGCYCPVGMV RNSKGICIHP DDCPCSFGDR EYEQGSVTSV GCNECTCIKG 

       850        860        870        880        890        900 
SWNCTQNECQ STCHVYGEGH FRTFDGESYS FDGLCQYTFL EDYCGQENGT FRILIESVPC 

       910        920        930        940        950        960 
CENGLTCSRK VIVTFQDQNI ILQDGKVTAV QTAESTDCRE RSANLYSIHT VGLYLIVKLL 

       970        980        990       1000       1010       1020 
NGIILIWDKY TKVSVILDPS WQNKVCGLCG NNNGDLKDDF TTRHSSVAAG ALEFANSWKT 

      1030       1040       1050       1060       1070       1080 
SQECSDTVTQ SFPCDSNPYC KAWAEKRCEI LRDDTFRDCH SKVDPTTYYD ACIEEACSCD 

      1090       1100       1110       1120       1130       1140 
MEGKYLGFCT AVAMYAEACN AAGVCVSWRK PNLCPVYCDY YNAPGECSWH YEPCGTVTAK 

      1150       1160       1170       1180       1190       1200 
TCKDQVIGQK FSSLLEGCYA KCPENAPYLD ENTMKCVQLS ECSCFYNDVI PAGGAVVDDC 

      1210       1220       1230       1240       1250       1260 
GRTCSCSAGE LECSETPPNS TTTTTATTAA VSTATTTSVL STSAAATRAS SSTSGSVETS 

      1270       1280       1290       1300       1310       1320 
VPATTSTSKA QAHITTASST ETSALNSTAV YPKATTREGL LSSSGPGAFV AERPDNTPRP 

      1330       1340       1350       1360       1370       1380 
AVSTTSAGST SARAATTSPG GSSGSSAPAS STSGRAATTT STSAATTTTT TTATTVGSAG 

      1390       1400       1410       1420       1430       1440 
SSAPTASSTA AGSGLREAAN ATSAPASTSG QPGASTGSSG TSSSVSSTAA ATTAGTTTAA 

      1450       1460       1470       1480       1490       1500 
SNETSAPAST AGPTSSATTA APASSSASSA TTPAETAGST TGPAVSTTSA GSTSARAATT 

      1510       1520       1530       1540       1550       1560 
SPGGSSGSSA PASSTSGRAA TTTSTATTTT TTTTTATTVG SAGSSAPTAS STAAGSGLRE 

      1570       1580       1590       1600       1610       1620 
AANATSAPAS TSGQPGASTG SSGTSSSVSS TAAATTAGTT TAASNETSAP ASTAGPTSSA 

      1630       1640       1650       1660       1670       1680 
TTAAPASSSA SSATTPAETA GSTTGPAVST TSAGSTSARA ATTSPGGSSG SSAPASSTSG 

      1690       1700       1710       1720       1730       1740 
RAATTTSTAT TTTTTTTTAT TVGSAGSSAP TASSTAAGSG LREAANATSA PASTSGQPGA 

      1750       1760       1770       1780       1790       1800 
STGSSGTSSS VSSTAAATTA GTTTAASNET SAPASTAGPT SSATTAAPAS SSASSATTPA 

      1810       1820       1830       1840       1850       1860 
ETAGSTTGPA VSTTSAGSTS ARAATTSPGG SSGSSAPASS TSGRAATTTS TATTTTTTTT 

      1870       1880       1890       1900       1910       1920 
TATTVGSAGS SAPTASSTAA GSGLREAANA TSAPASTSGQ PGASTGSSGT SSSVSSTAAA 

      1930       1940       1950       1960       1970       1980 
TTAGTTTAAS NETSAPASTA GPTSSATTAA PASSSASSAT TPAETAGSTT GPAVSTTSAG 

      1990       2000       2010       2020       2030       2040 
STSARAATTS PGGSSGSSAP ASSTSGRAAT TTSTATTTTT TTTTATTVGS AGSSAPTASS 

      2050       2060       2070       2080       2090       2100 
TAAGSGLREA ANATSAPAST SGQPGASTGS SGTSSSVSST AAATTAGTTT AASNETSAPA 

      2110       2120       2130       2140       2150       2160 
STAGPTSSAT TAAPASSSAS SATTPAETAG STTGPAVSTT SAGSTSARAA TTSPGGSSGS 

      2170       2180       2190       2200       2210       2220 
SAPASSTSGR AATTTSTATT TTTTTTTATT VGSAGSSAPT ASSTAAGSGL REAANATSAP 

      2230       2240       2250       2260       2270       2280 
ASTSGQPGAS TGSSGTSSSV SSTAAATTAG TTTAASNETS APASTAGPTS SATTAAPASS 

      2290       2300       2310       2320       2330       2340 
SASSATTPAE TAGSTTGPAV STTSAGSTSA RAATTSPGGS SGSSAPASST SGRAATTTST 

      2350       2360       2370       2380       2390       2400 
ATTTTTTTTT ATTVGSAGSS APTASSTAAG SGLREAANAT SAPASTSGQP GASTGSSGTS 

      2410       2420       2430       2440       2450       2460 
SSVSSTAAAT TAGTTTAASN ETSAPASTAG PTSSATTAAP ASSSASSATT PAETAGSTTG 

      2470       2480       2490       2500       2510       2520 
PAVSTTSAGS TSARAATTSP GGSSGSSAPA SSTSGRAATT TSTATTTTTT TTTATTVGSA 

      2530       2540       2550       2560       2570       2580 
GSSAPTASST AAGSGLREAA NATSAPASTS GQPGASTGSS GTSSSVSSTA AATTAGTTTA 

      2590       2600       2610       2620       2630       2640 
ASNETSAPAS TAGPTSSATT AAPASSSASS ATTPAETAGS TTGPAVSTTS AGSTSARAAT 

      2650       2660       2670       2680       2690       2700 
TSPGGSSGSS APASSTSGRA ATTTSTATTT TTTTTTATTV GSAGSSAPTA SSTAAGSGLR 

      2710       2720       2730       2740       2750       2760 
EAANATSAPA STSGQPGAST GSSGTSSSVS STAAATTAGT TTAASNETSA PASTAGPTSS 

      2770       2780       2790       2800       2810       2820 
ATTAAPASSS ASSATTPAET AGSTTGPAVS TTSAGSTSAR AATTSPGGSS GSSAPASSTS 

      2830       2840       2850       2860       2870       2880 
GRAATTTSTA TTTTTTTTTA TTVGSAGSSA PTASSTAAGS GLREAANATS APASTSGQPG 

      2890       2900       2910       2920       2930       2940 
ASTGSSGTSS SVSSTAAATT AGTTTAASNE TSAPASTAGP TSSATTAAPA SSSASSATTP 

      2950       2960       2970       2980       2990       3000 
AETAGSTTGP AVSTTSAGST SARAATTSPG GSSGSSAPAS STSGRAATTT STATTTTTTT 

      3010       3020       3030       3040       3050       3060 
TTATTVGSAG SSAPTASSTA AGSGLREAAN ATSAPASTSG QPGASTGSSG TSSSVSSTAA 

      3070       3080       3090       3100       3110       3120 
ATTAGTTTAA SNETSAPAST AGPTSSATTA APASSSASSA TTPAETAGST TGPAVSTTSA 

      3130       3140       3150       3160       3170       3180 
GSTSARAATT SPGGSSGSSA PASSTSGRAA TTTSTATTTT TTTTTATTVG SAGSSAPTAS 

      3190       3200       3210       3220       3230       3240 
STAAGSGLRE AANATSAPAS TSGQPGASTG SSGTSSSVSS TAAATTAGTT TAASNETSAP 

      3250       3260       3270       3280       3290       3300 
ASTAGPTSSA TTAAPASSSA SSATTPAETA GSTTGPAVST TSAGSTSARA ATTSPGGSSG 

      3310       3320       3330       3340       3350       3360 
SSAPASSTSG RAATTTSTAT TTTTTTTTAT TVGSAGSSAP TASSTAAGSG LREAANATSA 

      3370       3380       3390       3400       3410       3420 
PASTSGQPGA STGSSGTSSS VSSTAAATTA GTTTAASNET SAPASTAGPT SSATTAAPAS 

      3430       3440       3450       3460       3470       3480 
SSASSATTPA ETAGSTTGPA VSTTSAGSTS ARAATTSPGG SSGSSAPASS TSGRAATTTS 

      3490       3500       3510       3520       3530       3540 
TATTTTTTTT TATTVGSAGS SAPTASSTAA GSGLREAANA TSAPASTSGQ PGASTGSSGT 

      3550       3560       3570       3580       3590       3600 
SSSVSSTAAA TTAGTTTAAS NETSAPASTA GPTSSATTAA PASSSASSAT TPAETAGSTT 

      3610       3620       3630       3640       3650       3660 
GPAVSTTSAG STSARAATTS PGGSSGSSAP ASSTSGRAAT TTSTATTTTT TTTTATTVGS 

      3670       3680       3690       3700       3710       3720 
AGSSAPTASS TAAGSGLREA ANATSAPAST SGQPGASTGS SGTSSSVSST AAATTAGTTT 

      3730       3740       3750       3760       3770       3780 
AASNETSAPA STAGPTSSAT TAAPASSSAS SATTPAETAG STTGPAVSTT SAGSTSARAA 

      3790       3800       3810       3820       3830       3840 
TTSPGGSSGS SAPASSTSGR AATTTSTATT TTTTTTTATT VGSAGSSAPT ASSTAAGSGL 

      3850       3860       3870       3880       3890       3900 
REAANATSAP ASTSGQPGAS TGSSGTSSSV SSTAAATTAG TTTAASNETS APASTAGPTS 

      3910       3920       3930       3940       3950       3960 
SATTAAPASS SASSATTPAE TAGSTTGPAV STTSAGSTSA RAATTSPGGS SGSSAPASST 

      3970       3980       3990       4000       4010       4020 
SGRAATTTST ATTTTTTTTT ATTVGSAGSS APTASSTAAG SGLREAANAT SAPASTSGQP 

      4030       4040       4050       4060       4070       4080 
GASTGSSGTS SSVSSTAAAT TAGTTTAASN ETSAPASTAG PTSSATTAAP ASSSASSATT 

      4090       4100       4110       4120       4130       4140 
PAETAGSTTG PAVSTTSAGS TSARAATTSP GGSSGSSAPA SSTSGRAATT TSTATTTTTT 

      4150       4160       4170       4180       4190       4200 
TTTATTVGSA GSSAPTASST AAGSGLREAA NATSAPASTS GQPGASTGSS GTSSSVSSTA 

      4210       4220       4230       4240       4250       4260 
AATTAGTTTA ASNETSAPAS TAGPTSSATT AAPASSSASS ATTPAETAGS TTGPAVSTTS 

      4270       4280       4290       4300       4310       4320 
AGSTSARAAT TSPGGSSGSS APASSTSGRA ATTTSTATTT TTTTTTATTV GSAGSSAPTA 

      4330       4340       4350       4360       4370       4380 
SSTAAGSGLR EAANATSAPA STSGQPGAST GSSGTSSSVS STAAATTAGT TTAASNETSA 

      4390       4400       4410       4420       4430       4440 
PASTAGPTSS ATTAAPASSS ASSATTPAET AGSTTGPAVS TTSAGSTSAR AATTSPGGSS 

      4450       4460       4470       4480       4490       4500 
GSSAPASSTS GRAATTTSTA TTTTTTTTTA TTVGSAGSSA PTASSTAAGS GLREAANATS 

      4510       4520       4530       4540       4550       4560 
APASTSGQPG ASTGSSGTSS SVSSTAAATT AGTTTAASNE TSAPASTAGP TSSATTAAPA 

      4570       4580       4590       4600       4610       4620 
SSSASSATTP AETAGSTTGP AVSTTSAGST SARAATTSPG GSSGSSAPAS STSGRAATTT 

      4630       4640       4650       4660       4670       4680 
STATTTTTTT TTATTVGSAG SSAPTASSTA AGSGLREAAN ATSAPASTSG QPGASTGSSG 

      4690       4700       4710       4720       4730       4740 
TSSSVSSTAA ATTAGTTTAA SNETSAPAST AGPTSSATTA APASSSASSA TTPAETAGST 

      4750       4760       4770       4780       4790       4800 
TGPAVSTTSA GSTSARAATT SPGGSSGSSA PASSTSGRAA TTTSTATTTT TTTTTATTVG 

      4810       4820       4830       4840       4850       4860 
SAGSSAPTAS STAAGSGLRE AANATSAPAS TSGQPGASTG SSGTSSSVSS TAAATTAGTT 

      4870       4880       4890       4900       4910       4920 
TAASNETSAP ASTAGPTSSA TTAAPASSSA SSATTPAETA GSTTGPAVST TSAGSTSARA 

      4930       4940       4950       4960       4970       4980 
ATTSPGGSSG SSAPASSTSG RAATTTSTAT TTTTTTTTAT TVGSAGSSAP TASSTAAGSG 

      4990       5000       5010       5020       5030       5040 
LREAANATSA PASTSGQPGA STGSSGTSSS VSSTAAATTA GTTTAASNET SAPASTAGPT 

      5050       5060       5070       5080       5090       5100 
SSATTAAPAS SSASSATTPA ETAGSTTGPA VSTTSAGSTS ARAATTSPGG SSGSSAPASS 

      5110       5120       5130       5140       5150       5160 
TSGRAATTTS TATTTTTTTT TATTVGSAGS SAPTASSTAA GSGLREAANA TSAPASTSGQ 

      5170       5180       5190       5200       5210       5220 
PGASTGSSGT SSSVSSTAAA TTAGTTTAAS NETSAPASTA GPTSSATTAA PASSSASSAT 

      5230       5240       5250       5260       5270       5280 
TPAETAGSTT GPAVSTTSAG STSARAATTS PGGSSGSSAP ASSTSGRAAT TTSTATTTTT 

      5290       5300       5310       5320       5330       5340 
TTTTATTVGS AGSSAPTASS TAAGSGLREA ANATSAPAST SGQPGASTGS SGTSSSVSST 

      5350       5360       5370       5380       5390       5400 
AAATTAGTTT AASNETSAPA STAGPTSSAT TAAPASSSAS SATTPAETAG STTGPAVSTT 

      5410       5420       5430       5440       5450       5460 
SAGSTSARAA TTSPGGSSGS SAPASSTSGR AATTTSTATT TTTTTTTATT VGSAGSSAPT 

      5470       5480       5490       5500       5510       5520 
ASSTAAGSGL REAANATSAP ASTSGQPGAS TGSSGTSSSV SSTAAATTAG TTTAASNETS 

      5530       5540       5550       5560       5570       5580 
APASTAGPTS SATTAAPASS SASSATTPAE TAGSTTGPAV STTSAGSTSA RAATTSPGGS 

      5590       5600       5610       5620       5630       5640 
SGSSAPASST SGRAATTTST ATTTTTTTTT ATTVGSAGSS APTASSTAAG SGLREAANAT 

      5650       5660       5670       5680       5690       5700 
SAPASTSGQP GASTGSSGTS SSVSSTAAAT TAGTTTAASN ETSAPASTAG PTSSATTAAP 

      5710       5720       5730       5740       5750       5760 
ASSSASSATT PAETAGSTTG PAVSTTSAGS TSARAATTSP GGSSGSSAPA SSTSGRAATT 

      5770       5780       5790       5800       5810       5820 
TSTATTTTTT TTTATTVGSA GSSAPTASST AAGSGLREAA NATSAPASTS GQPGASTGSS 

      5830       5840       5850       5860       5870       5880 
GTSSSVSSTA AATTAGTTTA ASNETSAPAS TAGPTSSATT AAPASSSASS ATTPAETAGS 

      5890       5900       5910       5920       5930       5940 
TTGPAVSTTS AGSTSARAAT TSPGGSSGSS APASSTSGRA ATTTSTATTT TTTTTTATTV 

      5950       5960       5970       5980       5990       6000 
GSAGSSAPTA SSTAAGSGLR EAANATSAPA STSGQPGAST GSSGTSSSVS STAAATTAGT 

      6010       6020       6030       6040       6050       6060 
TTAASNETSA PASTAGPTSS ATTAAPASSS ASSATTPAET AGSTTGPAVS TTSAGSTSAR 

      6070       6080       6090       6100       6110       6120 
AATTSPGGSS GSSAPASSTS GRAATTTSTA TTTTTTTTTA TTVGSAGSSA PTASSTAAGS 

      6130       6140       6150       6160       6170       6180 
GLREAANATS APASTSGQPG ASTGSSGTSS SVSSTAAATT AGTTTAASNE TSAPASTAGP 

      6190       6200       6210       6220       6230       6240 
TSSATTAAPA SSSASSATTP AETAGSTTGP AVSTTSAGST SARAATTSPG GSSGSSAPAS 

      6250       6260       6270       6280       6290       6300 
STSGRAATTT STATTTTTTT TTATTVGSAG SSAPTASSTA AGSGLREAAN ATSAPASTSG 

      6310       6320       6330       6340       6350       6360 
QPGASTGSSG TSSSVSSTAA ATTAGTTTAA SNETSAPAST AGPTSSATTA APASSSASSA 

      6370       6380       6390       6400       6410       6420 
TTPAETAGST TGPAVSTTSA GSTSARAATT SPGGSSGSSA PASSTSGRAA TTTSTATTTT 

      6430       6440       6450       6460       6470       6480 
TTTTTATTVG SAGSSAPTAS STAAGSGLRE AANATSAPAS TSGQPGASTG SSGTSSSVSS 

      6490       6500       6510       6520       6530       6540 
TAAATTAGTT TAASNETSAP ASTAGPTSSA TTAAPASSSA SSATTPAETA GSTTGPAVST 

      6550       6560       6570       6580       6590       6600 
TSAGSTSARA ATTSPGGSSG SSAPASSTSG RAATTTSTAT TTTTTTTTAT TVGSAGSSAP 

      6610       6620       6630       6640       6650       6660 
TASSTAAGSG LREAANATSA PASTSGQPGA STGSSGTSSS VSSTAAATTA GTTTAASNET 

      6670       6680       6690       6700       6710       6720 
SAPASTAGPT SSATTAAPAS SSASSATTPA ETAGSTTGPA VSTTSAGSTS ARAATTSPGG 

      6730       6740       6750       6760       6770       6780 
SSGSSAPASS TSGRAATTTS TATTTTTTTT TATTVGSAGS SAPTASSTAA GSGLREAANA 

      6790       6800       6810       6820       6830       6840 
TSAPASTSGQ PGASTGSSGT SSSVSSTAAA TTAGTTTAAS NETSAPASTA GPTSSATTAA 

      6850       6860       6870       6880       6890       6900 
PASSSASSAT TPAETAGSTT GPAVSTTSAG STSARAATTS PGGSSGSSAP ASSTSGRAAT 

      6910       6920       6930       6940       6950       6960 
TTSTATTTTT TTTTATTVGS AGSSAPTASS TAAGSGLREA ANATSAPAST SGQPGASTGS 

      6970       6980       6990       7000       7010       7020 
SGTSSSVSST AAATTAGTTT AASNETSAPA STAGPTSSAT TAAPASSSAS SATTPAETAG 

      7030       7040       7050       7060       7070       7080 
STTGPAVSTT SAGSTSARAA TTSPGGSSGS SAPASSTSGR AATTTSTATT TTTTTTTATT 

      7090       7100       7110       7120       7130       7140 
VGSAGSSAPT ASSTAAGSGL REAANATSAP VSTSGQPGAS TGSSGTSSSV SSTAAATTAG 

      7150       7160       7170       7180       7190       7200 
TTTAASNETS APASTAGPTS SATTAAPASS SASSATTPAE TAGSTTGPAV STTSAGSTSA 

      7210       7220       7230       7240       7250       7260 
RAATTSPGGS SGSSSLAIST MSVSSSSFIS PSGHPVPSTA SVAFLSSPSV IKTGGTTGTT 

      7270       7280       7290       7300       7310       7320 
AKSNETTGRT TSMPASTSVA PGVTTSPNIS QPECPDSLPP TPVCHGPLGE EKSPGDVWIS 

      7330       7340       7350       7360       7370       7380 
NCHQCTCTEK QAVDCKPKEC PSPPTCKDGE KLMKFKSNDS CCEIGHCEPR TCLFNNTDYA 

      7390       7400       7410       7420       7430       7440 
IGSSFDDPSN PCLSYTCNPT GLVAVVQDCP KQTWCAEEER IYDSNKCCYK CKNDCRTTPV 

      7450       7460       7470       7480       7490       7500 
NVTVKYNGCR KRVEMARCIG ECKRSVKYNY ETFQLENSCS CCREENYEFR DIALECSDGS 

      7510       7520 
TIPYRYRHTT TCSCRDQCEQ SKAS 

« Hide

Isoform 2 (Smgc) [UniParc].

See Q6JHY2.

Isoform 3 [UniParc].

See Q6JHY2.

Isoform 4 [UniParc].

See Q6JHY2.

Isoform 5 (t-Smgc) [UniParc].

See Q6JHY2.

Isoform 6 [UniParc].

See Q6JHY2.

References

« Hide 'large scale' references
[1]"The gene encoding mouse Muc19: cDNA, genomic organization and relationship to Smgc."
Culp D.J., Latchney L.R., Fallon M.A., Denny P.A., Denny P.C., Couwenhoven R.I., Chuang S.
Physiol. Genomics 19:303-318(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
Strain: NFS.
Tissue: Sublingual gland.
[2]"The sld mutation is specific for sublingual salivary mucous cells and disrupts apomucin gene expression."
Fallon M.A., Latchney L.R., Hand A.R., Johar A., Denny P.A., Georgel P.T., Denny P.C., Culp D.J.
Physiol. Genomics 14:95-106(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6711-7524, TISSUE SPECIFICITY.
Strain: Swiss Webster.
Tissue: Sublingual gland.
[3]"Genome-wide search and identification of a novel gel-forming mucin MUC19/Muc19 in glandular tissues."
Chen Y., Zhao Y.H., Kalaslavadi T.B., Hamati E., Nehrke K., Le A.D., Ann D.K., Wu R.
Am. J. Respir. Cell Mol. Biol. 30:155-165(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6918-7524, TISSUE SPECIFICITY.
Strain: C57BL/6 X DBA/2.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7276-7524.
Strain: FVB/N.
Tissue: Salivary gland.
+Additional computationally mapped references.

Web resources

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY570293 mRNA. Translation: AAS77382.2.
EU089955 mRNA. Translation: ABU50842.1.
EU089956 mRNA. Translation: ABU50843.1.
EU089957 mRNA. Translation: ABU50844.1.
EU089959 mRNA. Translation: ABU50846.1.
AY172172 mRNA. Translation: AAO38851.1.
AY193891 mRNA. Translation: AAO49800.1. Sequence problems.
BC061502 mRNA. Translation: AAH61502.1.
RefSeqNP_997126.2. NM_207243.2. [Q6PZE0-1]
UniGeneMm.486225.

3D structure databases

ProteinModelPortalQ6PZE0.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ6PZE0.

Proteomic databases

MaxQBQ6PZE0.
PRIDEQ6PZE0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID239611.
KEGGmmu:239611.
UCSCuc007xie.1. mouse. [Q6PZE0-1]

Organism-specific databases

CTD283463.
MGIMGI:2676278. Muc19.

Phylogenomic databases

eggNOGNOG12793.
InParanoidQ6PZE0.

Gene expression databases

BgeeQ6PZE0.
CleanExMM_MUC19.
GenevestigatorQ6PZE0.

Family and domain databases

InterProIPR006207. Cys_knot_C.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view]
PfamPF08742. C8. 3 hits.
PF01826. TIL. 1 hit.
PF00094. VWD. 3 hits.
[Graphical view]
SMARTSM00832. C8. 2 hits.
SM00041. CT. 1 hit.
SM00214. VWC. 2 hits.
SM00216. VWD. 3 hits.
[Graphical view]
SUPFAMSSF57567. SSF57567. 3 hits.
PROSITEPS01185. CTCK_1. 1 hit.
PS01225. CTCK_2. 1 hit.
PS01208. VWFC_1. 1 hit.
PS50184. VWFC_2. 1 hit.
PS51233. VWFD. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio384199.
SOURCESearch...

Entry information

Entry nameMUC19_MOUSE
AccessionPrimary (citable) accession number: Q6PZE0
Secondary accession number(s): A7UN62 expand/collapse secondary AC list , A7UN63, A7UN64, A7UN66, Q6P7U5, Q6Y0X6, Q80UR5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: October 25, 2004
Last modified: June 11, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot