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Protein
Submitted name:

ALDH3A1 protein

Gene

ALDH3A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ALDH3A1 proteinImported
Gene namesi
Name:ALDH3A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24697.

PTM / Processingi

Proteomic databases

PaxDbiQ6PKA6.
PeptideAtlasiQ6PKA6.
PRIDEiQ6PKA6.

Expressioni

Gene expression databases

GenevisibleiQ6PKA6. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000225740.

Structurei

3D structure databases

ProteinModelPortaliQ6PKA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini78 – 484407AldedhInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili82 – 10928Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2456. Eukaryota.
COG1012. LUCA.
HOGENOMiHOG000271515.
HOVERGENiHBG050483.
KOiK00129.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR012394. Aldehyde_DH_NAD(P).
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
PIRSFiPIRSF036492. ALDH. 1 hit.
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6PKA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EVQRTPHPTF EYFFFLSRKL PGQELQGLNG REAGSLNTSP LGSCRSRSPS
60 70 80 90 100
YRERLCQRRH EQDQRGREAR PRRLQLGRTR PLQFRIQQLE ALQRLIQEQE
110 120 130 140 150
QELVGALAAD LHKNEWNAYY EEVVYVLEEI EYMIQKLPEW AADEPVEKTP
160 170 180 190 200
QTQQDELYIH SEPLGVVLVI GTWNYPFNLT IQPMVGAIAA GNAVVLKPSE
210 220 230 240 250
LSENMASLLA TIIPQYLDKD LYPVINGGVP ETTELLKERF DHILYTGSTG
260 270 280 290 300
VGKIIMTAAA KHLTPVTLEL GGKSPCYVDK NCDLDVACRR IAWGKFMNSG
310 320 330 340 350
QTCVAPDYIL CDPSIQNQIV EKLKKSLKEF YGEDAKKSRD YGRIISARHF
360 370 380 390 400
QRVMGLIEGQ KVAYGGTGDA ATRYIAPTIL TDVDPQSPVM QEEIFGPVLP
410 420 430 440 450
IVCVRSLEEA IQFINQREKP LALYMFSSND KVIKKMIAET SSGGVAANDV
460 470 480 490 500
IVHITLHSLP FGGVGNSGMG SYHGKKSFET FSHRRSCLVR PLMNDEGLKV
510
RYPPSPAKMT QH
Length:512
Mass (Da):57,510
Last modified:July 5, 2004 - v1
Checksum:i9316E56FCC008829
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC004102 mRNA. Translation: AAH04102.1.
RefSeqiNP_000682.3. NM_000691.4.
UniGeneiHs.531682.

Genome annotation databases

GeneIDi218.
KEGGihsa:218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC004102 mRNA. Translation: AAH04102.1.
RefSeqiNP_000682.3. NM_000691.4.
UniGeneiHs.531682.

3D structure databases

ProteinModelPortaliQ6PKA6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000225740.

Proteomic databases

PaxDbiQ6PKA6.
PeptideAtlasiQ6PKA6.
PRIDEiQ6PKA6.

Protocols and materials databases

DNASUi218.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi218.
KEGGihsa:218.

Organism-specific databases

CTDi218.
PharmGKBiPA24697.

Phylogenomic databases

eggNOGiKOG2456. Eukaryota.
COG1012. LUCA.
HOGENOMiHOG000271515.
HOVERGENiHBG050483.
KOiK00129.

Miscellaneous databases

ChiTaRSiALDH3A1. human.
GenomeRNAii218.

Gene expression databases

GenevisibleiQ6PKA6. HS.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR012394. Aldehyde_DH_NAD(P).
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
PIRSFiPIRSF036492. ALDH. 1 hit.
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6PKA6_HUMAN
AccessioniPrimary (citable) accession number: Q6PKA6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.