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Protein
Submitted name:

TBC1D1 protein

Gene

TBC1D1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
TBC1D1 proteinImported
Gene namesi
Name:TBC1D1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ6PJJ8.
PeptideAtlasiQ6PJJ8.

Expressioni

Gene expression databases

BgeeiENSG00000065882.
GenevisibleiQ6PJJ8. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000261439.

Structurei

3D structure databases

ProteinModelPortaliQ6PJJ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 106PIDInterPro annotationAdd BLAST80
Domaini532 – 726Rab-GAP TBCInterPro annotationAdd BLAST195

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili466 – 489Sequence analysisAdd BLAST24
Coiled coili812 – 881Sequence analysisAdd BLAST70

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4436. Eukaryota.
ENOG410YWJY. LUCA.
HOVERGENiHBG059376.
KOiK18341.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR021785. DUF3350.
IPR011993. PH_dom-like.
IPR006020. PTB/PI_dom.
IPR000195. Rab-GTPase-TBC_dom.
[Graphical view]
PfamiPF11830. DUF3350. 1 hit.
PF00640. PID. 1 hit.
PF00566. RabGAP-TBC. 1 hit.
[Graphical view]
SMARTiSM00462. PTB. 1 hit.
SM00164. TBC. 1 hit.
[Graphical view]
SUPFAMiSSF47923. SSF47923. 2 hits.
SSF50729. SSF50729. 1 hit.
PROSITEiPS01179. PID. 1 hit.
PS50086. TBC_RABGAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6PJJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IENHLISGHN IVQPTDIEEN RTMLFTIGQS EVYLISPDTK KIALEKNFKE
60 70 80 90 100
ISFCSQGIRH VDHFGFICRE SSGGGGFHFV CYVFQCTNEA LVDEIMMTLK
110 120 130 140 150
QAFTVAAVQQ TAKAPAQLCE GCPLQSLHKL CERIEGMNSS KTKLELQKHL
160 170 180 190 200
TTLTNQEQAT IFEEVQKLRP RNEQRENELI ISFLRCLYEE KQKEHIHIGE
210 220 230 240 250
MKQTSQMAAE NIGSELPPSA TRFRLDMLKN KAKRSLTESL ESILSRGNKA
260 270 280 290 300
RGLQEHSISV DLDSSLSSTL SNTSKEPSVC EKEALPISES SFKLLGSSED
310 320 330 340 350
LSSDSESHLP EEPAPLSPQQ AFRRRANTLS HFPIECQEPP QPARGSPGVS
360 370 380 390 400
QRKLMRYHSV STETPHERKD FESKANHLGD SGGTPVKTRR HSWRQQIFLR
410 420 430 440 450
VATPQKACDS SSRYEDYSEL GELPPRSPLE PVCEDGPFGP PPEEKKRTSR
460 470 480 490 500
ELRELWQKAI LQQILLLRME KENQKLQASE NDLLNKRLKL DYEEITPCLK
510 520 530 540 550
EVTTVWEKML STPGRSKIKF DMEKMHSAVG QGVPRHHRGE IWKFLAEQFH
560 570 580 590 600
LKHQFPSKQQ PKDVPYKELL KQLTSQQHAI LIDLGRTFPT HPYFSAQLGA
610 620 630 640 650
GQLSLYNILK AYSLLDQEVG YCQGLSFVAG ILLLHMSEEE AFKMLKFLMF
660 670 680 690 700
DMGLRKQYRP DMIILQIQMY QLSRLLHDYH RDLYNHLEEH EIGPSLYAAP
710 720 730 740 750
WFLTMFASQF PLGFVARVFD MIFLQGTEVI FKVALSLLGS HKPLILQHEN
760 770 780 790 800
LETIVDFIKS TLPNLGLVQM EKTINQVFEM DIAKQLQAYE VEYHVLQEEL
810 820 830 840 850
IDSSPLSDNQ RMDKLEKTNS SLRKQNLDLL EQLQVANGRI QSLEATIEKL
860 870 880 890 900
LSSESKLKQA MLTLELERSA LLQTVEELRR RSAEPSDREP ECTQPEPTGD
Length:900
Mass (Da):102,877
Last modified:July 5, 2004 - v1
Checksum:i2685321241656FC7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC014529 mRNA. Translation: AAH14529.1.
RefSeqiNP_055988.2. NM_015173.3.
UniGeneiHs.176503.

Genome annotation databases

GeneIDi23216.
KEGGihsa:23216.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC014529 mRNA. Translation: AAH14529.1.
RefSeqiNP_055988.2. NM_015173.3.
UniGeneiHs.176503.

3D structure databases

ProteinModelPortaliQ6PJJ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000261439.

Proteomic databases

PaxDbiQ6PJJ8.
PeptideAtlasiQ6PJJ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23216.
KEGGihsa:23216.

Organism-specific databases

CTDi23216.

Phylogenomic databases

eggNOGiKOG4436. Eukaryota.
ENOG410YWJY. LUCA.
HOVERGENiHBG059376.
KOiK18341.

Miscellaneous databases

ChiTaRSiTBC1D1. human.
GenomeRNAii23216.

Gene expression databases

BgeeiENSG00000065882.
GenevisibleiQ6PJJ8. HS.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR021785. DUF3350.
IPR011993. PH_dom-like.
IPR006020. PTB/PI_dom.
IPR000195. Rab-GTPase-TBC_dom.
[Graphical view]
PfamiPF11830. DUF3350. 1 hit.
PF00640. PID. 1 hit.
PF00566. RabGAP-TBC. 1 hit.
[Graphical view]
SMARTiSM00462. PTB. 1 hit.
SM00164. TBC. 1 hit.
[Graphical view]
SUPFAMiSSF47923. SSF47923. 2 hits.
SSF50729. SSF50729. 1 hit.
PROSITEiPS01179. PID. 1 hit.
PS50086. TBC_RABGAP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6PJJ8_HUMAN
AccessioniPrimary (citable) accession number: Q6PJJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 5, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.