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Q6PJF2 (Q6PJF2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   DomainImmunoglobulin domain SAAS SAAS003006
   Technical term3D-structure PDB 2AGJ PDB 1DN0 PDB 1QLR PDB 3EYF PDB 3EYO
Gene Ontology (GO)
None. [Check GOA]

Sequences

Sequence LengthMass (Da)Tools
Q6PJF2 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: F33A145A396BA285

FASTA23525,521
        10         20         30         40         50         60 
METPAQLLFL LLLWLPGTTG EIVLTQSPAT LSLSPGERAT LSCRASQIVS SAYLAWYQQK 

        70         80         90        100        110        120 
PGQAPRLLMF GSSSRATGIP DRFSGSGSGT DFTLTISRLE PEDFAVYYCQ QYGSSQGTFG 

       130        140        150        160        170        180 
PGTKVDIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS 

       190        200        210        220        230 
QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC 

« Hide

References

« Hide 'large scale' references
[1]"Three-dimensional structure of the Fab from a human IgM cold agglutinin."
Cauerhff A., Braden B.C., Carvalho J.G., Aparicio R., Polikarpov I., Leoni J., Goldbaum F.A.
J. Immunol. 165:6422-6428(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.28 ANGSTROMS) OF 21-235.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lung EMBL AAH16380.1.
[3]"Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody."
Ramsland P.A., Terzyan S.S., Cloud G., Bourne C.R., Farrugia W., Tribbick G., Geysen H.M., Moomaw C.R., Slaughter C.A., Edmundson A.B.
Biochem. J. 395:473-481(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 21-235.
[4]"Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus."
Thomson C.A., Bryson S., McLean G.R., Creagh A.L., Pai E.F., Schrader J.W.
EMBO J. 27:2592-2602(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 21-235.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC016380 mRNA. Translation: AAH16380.1.
UniGeneHs.449609.
Hs.719895.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1DN0X-ray2.28A/C21-235[»]
1QLRX-ray2.83A/C21-235[»]
2AGJX-ray2.60L21-235[»]
3EYFX-ray2.30A/C21-235[»]
3EYOX-ray2.50A/C21-235[»]
ProteinModelPortalQ6PJF2.
SMRQ6PJF2. Positions 21-235.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ6PJF2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG018013.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ6PJF2.

Entry information

Entry nameQ6PJF2_HUMAN
AccessionPrimary (citable) accession number: Q6PJF2
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.