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Protein
Submitted name:

Igh protein

Gene

Igh

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Igh proteinImported
Gene namesi
Name:IghImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 465446Sequence analysisPRO_5004277982Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi41 ↔ 115Combined sources
Disulfide bondi162 ↔ 217Combined sources

Proteomic databases

PeptideAtlasiQ6PJB2.
PRIDEiQ6PJB2.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YNKX-ray2.10H21-237[»]
1YNLX-ray1.70H21-237[»]
2R6Pelectron microscopy24.00D/F21-235[»]
ProteinModelPortaliQ6PJB2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6PJB2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 134116Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini141 – 23393Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini256 – 355100Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini364 – 46097Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG005814.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00407. IGc1. 3 hits.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 4 hits.
PROSITEiPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PJB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGWGWVFLFL LSVTAGVHTQ VQLKQSGAEL VKPGASVKLS CKASGYTFNS
60 70 80 90 100
YIMHWVKQRP GQGLEWIGYF SPYNDDTKCN EKFKGKATLT ADKSSSTAYM
110 120 130 140 150
ELSSLTSEDS AVYYCARGYY VFDYWGQGTT ITVSSAKTTA PSVYPLAPVC
160 170 180 190 200
GDTTGSSVTL GCLVKGYFPE PVTLTWNSGS LSSGVHTFPA VLQSDLYTLS
210 220 230 240 250
SSVTVTSSTW PSQSITCNVA HPASSTKVDK KIEPRGPTIK PCPPCKCPAP
260 270 280 290 300
NLLGGPSVFI FPPKIKDVLM ISLSPMVTCV VVDVSEDDPD VQISWFVNNV
310 320 330 340 350
EVLTAQTQTH REDYNSTLRV VSALPIQHQD WMSGKEFKCK VNNKALPAPI
360 370 380 390 400
ERTISKPKGS VRAPQVYVLP PPEEEMTKKQ VTLTCMVTDF MPEDIYVEWT
410 420 430 440 450
NNGKTELNYK NTEPVLDSDG SYFMYSKLRV EKKNWVERNS YSCSVVHEGL
460
HNHHTTKSFS RTPGK
Length:465
Mass (Da):51,329
Last modified:July 5, 2004 - v1
Checksum:i394F43C4E8DB3E21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC018280 mRNA. Translation: AAH18280.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC018280 mRNA. Translation: AAH18280.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YNKX-ray2.10H21-237[»]
1YNLX-ray1.70H21-237[»]
2R6Pelectron microscopy24.00D/F21-235[»]
ProteinModelPortaliQ6PJB2.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ6PJB2.
PRIDEiQ6PJB2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG005814.

Miscellaneous databases

EvolutionaryTraceiQ6PJB2.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 2 hits.
SM00407. IGc1. 3 hits.
SM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 4 hits.
PROSITEiPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6PJB2_MOUSE
AccessioniPrimary (citable) accession number: Q6PJB2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.