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Protein
Submitted name:

ARHGAP4 protein

Gene

ARHGAP4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ARHGAP4 proteinImported
Gene namesi
Name:ARHGAP4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ6PJ34.
PeptideAtlasiQ6PJ34.

Expressioni

Gene expression databases

BgeeiENSG00000089820.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359045.

Structurei

3D structure databases

ProteinModelPortaliQ6PJ34.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 105Rho-GAPInterPro annotationAdd BLAST105
Domaini156 – 215SH3InterPro annotationAdd BLAST60

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

eggNOGiENOG410INNV. Eukaryota.
ENOG410YF76. LUCA.
HOGENOMiHOG000039980.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
InterProiIPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTiSM00324. RhoGAP. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6PJ34-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PLFPPDLFGE LLASSELEAT AERVEHVSRL LWRLPAPVLV VLRYLFTFLN
60 70 80 90 100
HLAQYSDENM MDPYNLAVCF GPTLLPVPAG QDPVALQGRV NQLVQTLIVQ
110 120 130 140 150
PDRVFPPLTS LPGPVYEKCM APPSASCLGD AQLESLGADN EPELEAEMPA
160 170 180 190 200
QEDDLEGVVE AVACFAYTGR TAQELSFRRG DVLRLHERAS SDWWRGEHNG
210 220 230 240 250
MRGLIPHKYI TLPAGTEKQV VGAGLQTAGE SGSSPEGLLA SELVHRPEPC
260 270 280 290 300
TSPEAMGPSG HRRRCLVPAS PEQHVEVDKA VAQNMDSVFK ELLGKTSVRQ
310 320 330 340 350
GLGPASTTSP SPGPRSPKAP PSSRLGRNKG FSRGPGAPAS PSASHPQGLD

TTPKPH
Length:356
Mass (Da):38,212
Last modified:July 5, 2004 - v1
Checksum:i4BD168D612542598
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023626 mRNA. Translation: AAH23626.1.
UniGeneiHs.701324.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023626 mRNA. Translation: AAH23626.1.
UniGeneiHs.701324.

3D structure databases

ProteinModelPortaliQ6PJ34.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000359045.

Proteomic databases

PaxDbiQ6PJ34.
PeptideAtlasiQ6PJ34.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410INNV. Eukaryota.
ENOG410YF76. LUCA.
HOGENOMiHOG000039980.

Miscellaneous databases

ChiTaRSiARHGAP4. human.

Gene expression databases

BgeeiENSG00000089820.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
InterProiIPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTiSM00324. RhoGAP. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48350. SSF48350. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6PJ34_HUMAN
AccessioniPrimary (citable) accession number: Q6PJ34
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.