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Protein

NudC domain-containing protein 1

Gene

Nudcd1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
NudC domain-containing protein 1
Gene namesi
Name:Nudcd1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1914679. Nudcd1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003077051 – 582NudC domain-containing protein 1Add BLAST582

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei7PhosphoserineBy similarity1
Modified residuei387PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ6PIP5.
MaxQBiQ6PIP5.
PaxDbiQ6PIP5.
PeptideAtlasiQ6PIP5.
PRIDEiQ6PIP5.

PTM databases

PhosphoSitePlusiQ6PIP5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000038736.
CleanExiMM_NUDCD1.
GenevisibleiQ6PIP5. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042746.

Structurei

3D structure databases

ProteinModelPortaliQ6PIP5.
SMRiQ6PIP5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini272 – 360CSPROSITE-ProRule annotationAdd BLAST89

Sequence similaritiesi

Contains 1 CS domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4379. Eukaryota.
ENOG410XRII. LUCA.
GeneTreeiENSGT00390000007776.
HOGENOMiHOG000007751.
HOVERGENiHBG104995.
InParanoidiQ6PIP5.
OMAiHINIVLK.
OrthoDBiEOG091G08D1.
PhylomeDBiQ6PIP5.
TreeFamiTF323350.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR007052. CS_dom.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PfamiPF04969. CS. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS51203. CS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PIP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAANCSLRV KRPLLDPRFE GYKLSLEPLP CYQLELDAAV AEVKLRDDQY
60 70 80 90 100
TLEHMHAFGM YNYLHCDAWY QDSVYYIDNL GRIMNLTVML DTALGKPREV
110 120 130 140 150
FRLPTDVTAY DNRLCASIHF TSPSWVTLSD GTGRLYVIGT GDRGNSPEKW
160 170 180 190 200
EIMFNEELGN PFIIIHSISL LKAEEHSVAI LLLRIEKEEL DLKGSGFYVS
210 220 230 240 250
LEWVVVTKKK EDSKKYEITK HHVLRGKSVP HYAAIEPNGN GLMIVSYKSF
260 270 280 290 300
KVISGDQDLE ENMDEDRPEK IKVEPLYYWQ QSEDDLTVTV RLPESSTKED
310 320 330 340 350
IQIQFLPDNI NIKLKDIQVL EGKLYSSIDH EGSTWTIKEN DSLEISLIKK
360 370 380 390 400
NEGLMWPELV VGDKQGELLR DPAQCAAIAE RLMHLTSDEL NPNPDKEKPA
410 420 430 440 450
CNAQELEECD IFFEESSSLC RFDGNTLQTT HVVNLGSNQY LFSVIVDPKE
460 470 480 490 500
MPCFCLRHDV DALLWQPHCS KQDDMWEHIA TFNALGYVQA SKRDKKFFAC
510 520 530 540 550
APNYSYAALC ECLRRVFIYR QPTPMSTVLY NRKEGRHVGQ VAKQQVASLE
560 570 580
TNDPILGFQA TNERLFVLTT KNLFLIRVNT EN
Length:582
Mass (Da):66,705
Last modified:October 23, 2007 - v2
Checksum:iB62BB34C1F9F1A64
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti22Y → C in BAE39873 (PubMed:16141072).Curated1
Sequence conflicti22Y → C in BAE40093 (PubMed:16141072).Curated1
Sequence conflicti26 – 28LEP → FER in BAE39873 (PubMed:16141072).Curated3
Sequence conflicti26 – 28LEP → FER in BAE40093 (PubMed:16141072).Curated3
Sequence conflicti49Q → K in AAQ08822 (PubMed:14688378).Curated1
Sequence conflicti113R → L in BAC36947 (PubMed:16141072).Curated1
Sequence conflicti180I → V in AAQ08822 (PubMed:14688378).Curated1
Sequence conflicti257Q → K in BAC36947 (PubMed:16141072).Curated1
Sequence conflicti273Missing in AAQ08822 (PubMed:14688378).Curated1
Sequence conflicti302Q → R in AAH31583 (PubMed:15489334).Curated1
Sequence conflicti428Q → K in AAH31583 (PubMed:15489334).Curated1
Sequence conflicti441L → M in BAE39873 (PubMed:16141072).Curated1
Sequence conflicti441L → M in BAE40093 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF521132 mRNA. Translation: AAQ08822.1.
AK077673 mRNA. Translation: BAC36947.1.
AK167855 mRNA. Translation: BAE39873.1.
AK168122 mRNA. Translation: BAE40093.1.
BC031583 mRNA. Translation: AAH31583.1.
CCDSiCCDS27455.1.
RefSeqiNP_001107026.1. NM_001113554.1.
NP_080425.3. NM_026149.4.
UniGeneiMm.490404.

Genome annotation databases

EnsembliENSMUST00000038719; ENSMUSP00000042746; ENSMUSG00000038736.
GeneIDi67429.
KEGGimmu:67429.
UCSCiuc007vpq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF521132 mRNA. Translation: AAQ08822.1.
AK077673 mRNA. Translation: BAC36947.1.
AK167855 mRNA. Translation: BAE39873.1.
AK168122 mRNA. Translation: BAE40093.1.
BC031583 mRNA. Translation: AAH31583.1.
CCDSiCCDS27455.1.
RefSeqiNP_001107026.1. NM_001113554.1.
NP_080425.3. NM_026149.4.
UniGeneiMm.490404.

3D structure databases

ProteinModelPortaliQ6PIP5.
SMRiQ6PIP5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042746.

PTM databases

PhosphoSitePlusiQ6PIP5.

Proteomic databases

EPDiQ6PIP5.
MaxQBiQ6PIP5.
PaxDbiQ6PIP5.
PeptideAtlasiQ6PIP5.
PRIDEiQ6PIP5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000038719; ENSMUSP00000042746; ENSMUSG00000038736.
GeneIDi67429.
KEGGimmu:67429.
UCSCiuc007vpq.2. mouse.

Organism-specific databases

CTDi84955.
MGIiMGI:1914679. Nudcd1.

Phylogenomic databases

eggNOGiKOG4379. Eukaryota.
ENOG410XRII. LUCA.
GeneTreeiENSGT00390000007776.
HOGENOMiHOG000007751.
HOVERGENiHBG104995.
InParanoidiQ6PIP5.
OMAiHINIVLK.
OrthoDBiEOG091G08D1.
PhylomeDBiQ6PIP5.
TreeFamiTF323350.

Miscellaneous databases

ChiTaRSiNudcd1. mouse.
PROiQ6PIP5.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038736.
CleanExiMM_NUDCD1.
GenevisibleiQ6PIP5. MM.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR007052. CS_dom.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PfamiPF04969. CS. 1 hit.
[Graphical view]
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS51203. CS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNUDC1_MOUSE
AccessioniPrimary (citable) accession number: Q6PIP5
Secondary accession number(s): Q3THV3, Q71EC1, Q8BJZ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: November 2, 2016
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.