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Q6PIL8

- Q6PIL8_HUMAN

UniProt

Q6PIL8 - Q6PIL8_HUMAN

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Protein
Submitted name:

IGK@ protein

Gene
IGK@
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Protein family/group databases

MEROPSiI43.001.

Names & Taxonomyi

Protein namesi
Submitted name:
IGK@ proteinImported
Gene namesi
Name:IGK@Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ6PIL8.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1U6AX-ray2.81L21-236[»]
3DVGX-ray2.60A40-236[»]
3DVNX-ray2.70A/L40-236[»]
3EYQX-ray2.40C21-236[»]
3HI1X-ray2.90A/L21-236[»]
4OQTX-ray3.23L25-236[»]
ProteinModelPortaliQ6PIL8.
SMRiQ6PIL8. Positions 21-236.

Miscellaneous databases

EvolutionaryTraceiQ6PIL8.

Family & Domainsi

Keywords - Domaini

Immunoglobulin domainSAAS annotations

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PIL8-1 [UniParc]FASTAAdd to Basket

« Hide

METPAQLLFL LLLWLPDSTG ENVLTQSPGT LSLSPGERAT LSCRASQSLS    50
SSYLAWYQQK PGQAPRLLIY GVSSRATGIP DRFSGSGSGT DFTLTISRLE 100
PEDFAVYYCQ QYGTSRPITF GQGTRLDIKR TVAAPSVFIF PPSDEQLKSG 150
TASVVCLLNN FYPREAKVQW KVDNALQSGN SQESVTEQDS KDSTYSLSST 200
LTLSKADYEK HKVYACEVTH QGLSSPVTKS FNRGEC 236
Length:236
Mass (Da):25,834
Last modified:July 5, 2004 - v1
Checksum:i6647A9E77A3C0053
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC032451 mRNA. Translation: AAH32451.1.
UniGeneiHs.449609.
Hs.719895.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC032451 mRNA. Translation: AAH32451.1 .
UniGenei Hs.449609.
Hs.719895.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1U6A X-ray 2.81 L 21-236 [» ]
3DVG X-ray 2.60 A 40-236 [» ]
3DVN X-ray 2.70 A/L 40-236 [» ]
3EYQ X-ray 2.40 C 21-236 [» ]
3HI1 X-ray 2.90 A/L 21-236 [» ]
4OQT X-ray 3.23 L 25-236 [» ]
ProteinModelPortali Q6PIL8.
SMRi Q6PIL8. Positions 21-236.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I43.001.

Proteomic databases

PRIDEi Q6PIL8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG018013.

Miscellaneous databases

EvolutionaryTracei Q6PIL8.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view ]
SMARTi SM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. "Structure of the Fab fragment of F105, a broadly reactive anti-human immunodeficiency virus (HIV) antibody that recognizes the CD4 binding site of HIV type 1 gp120."
    Wilkinson R.A., Piscitelli C., Teintze M., Cavacini L.A., Posner M.R., Lawrence C.M.
    J. Virol. 79:13060-13069(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.81 ANGSTROMS) OF 21-236.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 40-236.
  4. "Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus."
    Thomson C.A., Bryson S., McLean G.R., Creagh A.L., Pai E.F., Schrader J.W.
    EMBO J. 27:2592-2602(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 21-236.
  5. Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 21-236.
  6. "Structure of the LINGO-1-Anti-LINGO-1 Li81 Antibody Complex Provides Insights into the Biology of LINGO-1 and the Mechanism of Action of the Antibody Therapy."
    Pepinsky R.B., Arndt J.W., Quan C., Gao Y., Quintero-Monzon O., Lee X., Mi S.
    J. Pharmacol. Exp. Ther. 350:110-123(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.23 ANGSTROMS) OF 25-236.

Entry informationi

Entry nameiQ6PIL8_HUMAN
AccessioniPrimary (citable) accession number: Q6PIL8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 3, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3