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Protein
Submitted name:

Baculoviral IAP repeat-containing 8

Gene

BIRC8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiQ6PIA0.

Names & Taxonomyi

Protein namesi
Submitted name:
Baculoviral IAP repeat-containing 8Imported
Gene namesi
Name:BIRC8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25365.

PTM / Processingi

Proteomic databases

PaxDbiQ6PIA0.
PRIDEiQ6PIA0.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CASP9P552113EBI-2129837,EBI-516799
MAGED1Q9Y5V33EBI-2129837,EBI-716006

Protein-protein interaction databases

IntActiQ6PIA0. 3 interactors.
STRINGi9606.ENSP00000412957.

Structurei

3D structure databases

ProteinModelPortaliQ6PIA0.
SMRiQ6PIA0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 224RING-typeInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG1101. Eukaryota.
ENOG410YPNM. LUCA.
HOVERGENiHBG104450.
KOiK16061.

Family and domain databases

CDDicd00022. BIR. 1 hit.
Gene3Di1.10.1170.10. 2 hits.
InterProiIPR001370. BIR_rpt.
IPR001841. Znf_RING.
[Graphical view]
PfamiPF00653. BIR. 1 hit.
[Graphical view]
SMARTiSM00238. BIR. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS01282. BIR_REPEAT_1. 1 hit.
PS50143. BIR_REPEAT_2. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PIA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGYEARLIT FGTWMYSVNK EQLARAGFYA IGQEDKVQCF HCGGGLANWK
60 70 80 90 100
PKEDPWEQHA KWYPGCKYLL EEKGHEYINN IHLTRSLEGA LVQTTKKTPS
110 120 130 140 150
LTKRISDTIF PNPMLQEAIR MGFDFKDVKK IMEERIQTSG SNYKTLGVLV
160 170 180 190 200
ADLVSAQKDT TENELNQTSL QREISPEEPL RRLQEEKLCK ICMDRHIAVV
210 220 230
FIPCGHLVTC KQCAEAVDRC PMCSMVIDFK QRVFMS
Length:236
Mass (Da):27,077
Last modified:July 5, 2004 - v1
Checksum:iDF38350311FDAFBF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC039318 mRNA. Translation: AAH39318.1.
RefSeqiNP_203127.3. NM_033341.4.
UniGeneiHs.348263.

Genome annotation databases

GeneIDi112401.
KEGGihsa:112401.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC039318 mRNA. Translation: AAH39318.1.
RefSeqiNP_203127.3. NM_033341.4.
UniGeneiHs.348263.

3D structure databases

ProteinModelPortaliQ6PIA0.
SMRiQ6PIA0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6PIA0. 3 interactors.
STRINGi9606.ENSP00000412957.

Proteomic databases

PaxDbiQ6PIA0.
PRIDEiQ6PIA0.

Protocols and materials databases

DNASUi112401.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi112401.
KEGGihsa:112401.

Organism-specific databases

CTDi112401.
PharmGKBiPA25365.

Phylogenomic databases

eggNOGiKOG1101. Eukaryota.
ENOG410YPNM. LUCA.
HOVERGENiHBG104450.
KOiK16061.

Enzyme and pathway databases

SignaLinkiQ6PIA0.

Miscellaneous databases

GenomeRNAii112401.

Family and domain databases

CDDicd00022. BIR. 1 hit.
Gene3Di1.10.1170.10. 2 hits.
InterProiIPR001370. BIR_rpt.
IPR001841. Znf_RING.
[Graphical view]
PfamiPF00653. BIR. 1 hit.
[Graphical view]
SMARTiSM00238. BIR. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS01282. BIR_REPEAT_1. 1 hit.
PS50143. BIR_REPEAT_2. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6PIA0_HUMAN
AccessioniPrimary (citable) accession number: Q6PIA0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.