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Q6PH81 (CP087_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0547 protein C16orf87
Gene names
Name:C16orf87
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length154 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the UPF0547 family.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   DomainCoiled coil
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionprotein binding

Inferred from physical interaction PubMed 23752268. Source: IntAct

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

HDAC1Q135473EBI-6598617,EBI-301834

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q6PH81-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q6PH81-2)

The sequence of this isoform differs from the canonical sequence as follows:
     55-115: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 154154UPF0547 protein C16orf87
PRO_0000326521

Regions

Coiled coil104 – 13229 Potential

Amino acid modifications

Modified residue911Phosphoserine Ref.4

Natural variations

Alternative sequence55 – 11561Missing in isoform 2.
VSP_032670

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 016A2E075FF60223

FASTA15417,799
        10         20         30         40         50         60 
MSATRAKKVK MATKSCPECD QQVPVACKSC PCGYIFISRK LLNAKHSEKS PPSTENKHEA 

        70         80         90        100        110        120 
KRRRTERVRR EKINSTVNKD LENRKRSRSN SHSDHIRRGR GRPKSASAKK HEEEREKQEK 

       130        140        150 
EIDIYANLSD EKAFVFSVAL AEINRKIINQ RLIL 

« Hide

Isoform 2 [UniParc].

Checksum: 30DB292DF93014E8
Show »

FASTA9310,431

References

[1]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Tissue: Endometrium.
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[4]"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-91, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX647945 mRNA. Translation: CAH56192.1.
CH471092 Genomic DNA. Translation: EAW82689.1.
BC056676 mRNA. Translation: AAH56676.1.
CCDSCCDS10724.1. [Q6PH81-1]
RefSeqNP_001001436.1. NM_001001436.2. [Q6PH81-1]
UniGeneHs.406551.

3D structure databases

ProteinModelPortalQ6PH81.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid132622. 4 interactions.
IntActQ6PH81. 2 interactions.

PTM databases

PhosphoSiteQ6PH81.

Polymorphism databases

DMDM74737667.

Proteomic databases

MaxQBQ6PH81.
PaxDbQ6PH81.
PRIDEQ6PH81.

Protocols and materials databases

DNASU388272.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000285697; ENSP00000285697; ENSG00000155330. [Q6PH81-1]
ENST00000394806; ENSP00000378285; ENSG00000155330. [Q6PH81-2]
GeneID388272.
KEGGhsa:388272.
UCSCuc002eek.1. human. [Q6PH81-1]

Organism-specific databases

CTD388272.
GeneCardsGC16M046835.
H-InvDBHIX0026956.
HGNCHGNC:33754. C16orf87.
HPAHPA041179.
neXtProtNX_Q6PH81.
PharmGKBPA162378458.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG26271.
HOGENOMHOG000060343.
HOVERGENHBG059456.
InParanoidQ6PH81.
OMASDMENRR.
OrthoDBEOG7NKKN7.
PhylomeDBQ6PH81.
TreeFamTF331719.

Gene expression databases

BgeeQ6PH81.
CleanExHS_C16orf87.
GenevestigatorQ6PH81.

Family and domain databases

InterProIPR018886. UPF0547.
[Graphical view]
PfamPF10571. UPF0547. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi388272.
NextBio101917.

Entry information

Entry nameCP087_HUMAN
AccessionPrimary (citable) accession number: Q6PH81
Secondary accession number(s): Q63HN9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM