Q6PH81 (CP087_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0547 protein C16orf87

Gene names

Name:

C16orf87

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	154 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the UPF0547 family.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Domain	Coiled coil
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q6PH81-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q6PH81-2)

The sequence of this isoform differs from the canonical sequence as follows:
     55-115: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 154	154	UPF0547 protein C16orf87		PRO_0000326521
Regions
	Coiled coil	104 – 132	29	Potential
Amino acid modifications
	Modified residue	91	1	Phosphoserine Ref.4
Natural variations
	Alternative sequence	55 – 115	61	Missing in isoform 2.		VSP_032670

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 016A2E075FF60223	FASTA	154	17,799
	10 20 30 40 50 60 MSATRAKKVK MATKSCPECD QQVPVACKSC PCGYIFISRK LLNAKHSEKS PPSTENKHEA 70 80 90 100 110 120 KRRRTERVRR EKINSTVNKD LENRKRSRSN SHSDHIRRGR GRPKSASAKK HEEEREKQEK 130 140 150 EIDIYANLSD EKAFVFSVAL AEINRKIINQ RLIL
	Isoform 2 [UniParc]. Checksum: 30DB292DF93014E8	FASTA	93	10,431
	10 20 30 40 50 60 MSATRAKKVK MATKSCPECD QQVPVACKSC PCGYIFISRK LLNAKHSEKS PPSTEKQEKE 70 80 90 IDIYANLSDE KAFVFSVALA EINRKIINQR LIL

References

[1]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Endometrium.
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[4]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-91, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX647945 mRNA. Translation: CAH56192.1. CH471092 Genomic DNA. Translation: EAW82689.1. BC056676 mRNA. Translation: AAH56676.1.
IPI	IPI00067538. IPI00744097.
RefSeq	NP_001001436.1. NM_001001436.2.
UniGene	Hs.406551.
3D structure databases
ProteinModelPortal	Q6PH81.
ModBase	Search...
PTM databases
PhosphoSite	Q6PH81.
Polymorphism databases
DMDM	74737667.
Proteomic databases
PaxDb	Q6PH81.
PRIDE	Q6PH81.
Protocols and materials databases
DNASU	388272.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000285697; ENSP00000285697; ENSG00000155330. ENST00000394806; ENSP00000378285; ENSG00000155330.
GeneID	388272.
KEGG	hsa:388272.
UCSC	uc002eek.1. human.
Organism-specific databases
CTD	388272.
GeneCards	GC16M046835.
H-InvDB	HIX0026956.
HGNC	HGNC:33754. C16orf87.
HPA	HPA041179.
neXtProt	NX_Q6PH81.
PharmGKB	PA162378458.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG26271.
HOGENOM	HOG000060343.
HOVERGEN	HBG059456.
InParanoid	Q6PH81.
OMA	LLNAKHP.
OrthoDB	EOG43N7F3.
Gene expression databases
Bgee	Q6PH81.
CleanEx	HS_C16orf87.
Genevestigator	Q6PH81.
Family and domain databases
InterPro	IPR018886. UPF0547. [Graphical view]
Pfam	PF10571. UPF0547. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	388272.
NextBio	101917.

Entry information

Entry name

CP087_HUMAN

Accession

Primary (citable) accession number: Q6PH81
Secondary accession number(s): Q63HN9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.