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Protein

T-complex protein 1 subunit delta

Gene

cct4

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.SAAS annotation

GO - Molecular functioni

GO - Biological processi

  • protein folding Source: InterPro
  • response to hypoxia Source: ZFIN
Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-390471. Association of TriC/CCT with target proteins during biosynthesis.
R-DRE-6814122. Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding.

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 1 subunit deltaUniRule annotation
Gene namesi
Name:cct4Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-040426-1421. cct4.

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000013475.

Interactioni

Protein-protein interaction databases

MINTiMINT-8283668.
STRINGi7955.ENSDARP00000025466.

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0358. Eukaryota.
COG0459. LUCA.
GeneTreeiENSGT00550000074956.
HOVERGENiHBG106507.
KOiK09496.
OMAiAYCVRAY.
OrthoDBiEOG091G05G4.
TreeFamiTF106332.

Family and domain databases

CDDicd03338. TCP1_delta. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012717. Chap_CCT_delta.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02342. chap_CCT_delta. 1 hit.
PROSITEiPS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PH46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEAVVAASG IKNKGSAYVD RDKPAQIRYS NINAGKAVAD AIRTSLGPKG
60 70 80 90 100
MDKMIQDGKG DVTITNDGAT ILKQMQVLHP AAKMMVELSK AQDIEAGDGT
110 120 130 140 150
TSVVVIAGAL LDACAKLLQK GIHPTIISES FQKAVDKGVE VLTSISTPLL
160 170 180 190 200
LSDRESLLNS ASTSLCSKVV SQNSSLLAPM SVDAVMKVID PATATSVDLR
210 220 230 240 250
DINVVKKLGG TIDDCELVDG MVLTQRVAST GVSRVEKAKI GLIQFCLSPP
260 270 280 290 300
KTDMDNQIVV SDYAQMDRVL REERAYILNL VKQVKKAGCT VLLIQKSILR
310 320 330 340 350
DALSDLALHF LNKMKIMVIK DIEREEIEFI CKTIGTKPIA HIDQFTPEML
360 370 380 390 400
GSAELVEEVS LDGSGKLVKI TGCASPGKTV SIVVRGSNKL VIEEAERSIH
410 420 430 440 450
DALCVIRCLV KKRALIAGGG APEIELALRL AEYARSLGGM EAYCVRAYAD
460 470 480 490 500
ALEVIPSTLA ENAGLNPIST VTELRNRHAQ GETTAGINVR KGGISNILEE
510 520 530
LVVQPLLVSI SALTLATETV RSILKIDDLV NTR
Length:533
Mass (Da):56,973
Last modified:July 5, 2004 - v1
Checksum:iF469DADB0BA0AF02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU693443 Genomic DNA. No translation available.
CU929072 Genomic DNA. No translation available.
BC056719 mRNA. Translation: AAH56719.1.
RefSeqiNP_956877.1. NM_200583.1.
UniGeneiDr.72266.

Genome annotation databases

EnsembliENSDART00000026409; ENSDARP00000025466; ENSDARG00000013475.
GeneIDi393555.
KEGGidre:393555.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU693443 Genomic DNA. No translation available.
CU929072 Genomic DNA. No translation available.
BC056719 mRNA. Translation: AAH56719.1.
RefSeqiNP_956877.1. NM_200583.1.
UniGeneiDr.72266.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-8283668.
STRINGi7955.ENSDARP00000025466.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000026409; ENSDARP00000025466; ENSDARG00000013475.
GeneIDi393555.
KEGGidre:393555.

Organism-specific databases

CTDi10575.
ZFINiZDB-GENE-040426-1421. cct4.

Phylogenomic databases

eggNOGiKOG0358. Eukaryota.
COG0459. LUCA.
GeneTreeiENSGT00550000074956.
HOVERGENiHBG106507.
KOiK09496.
OMAiAYCVRAY.
OrthoDBiEOG091G05G4.
TreeFamiTF106332.

Enzyme and pathway databases

ReactomeiR-DRE-390471. Association of TriC/CCT with target proteins during biosynthesis.
R-DRE-6814122. Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding.

Gene expression databases

BgeeiENSDARG00000013475.

Family and domain databases

CDDicd03338. TCP1_delta. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012717. Chap_CCT_delta.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02342. chap_CCT_delta. 1 hit.
PROSITEiPS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
PS00995. TCP1_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6PH46_DANRE
AccessioniPrimary (citable) accession number: Q6PH46
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.