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Protein

Repressor of RNA polymerase III transcription MAF1 homolog

Gene

maf1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Repressor of RNA polymerase III transcription MAF1 homolog
Gene namesi
Name:maf1
ORF Names:zgc:63803
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 11

Organism-specific databases

ZFINiZDB-GENE-040426-2788. maf1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 247247Repressor of RNA polymerase III transcription MAF1 homologPRO_0000213975Add
BLAST

Proteomic databases

PaxDbiQ6PGU2.

Expressioni

Gene expression databases

BgeeiQ6PGU2.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015577.

Family & Domainsi

Sequence similaritiesi

Belongs to the MAF1 family.Curated

Phylogenomic databases

eggNOGiKOG3104. Eukaryota.
COG5046. LUCA.
GeneTreeiENSGT00390000006896.
HOGENOMiHOG000185242.
HOVERGENiHBG052395.
InParanoidiQ6PGU2.
OMAiGNLWSFN.
OrthoDBiEOG776SQX.
PhylomeDBiQ6PGU2.
TreeFamiTF315149.

Family and domain databases

InterProiIPR015257. Maf1.
[Graphical view]
PANTHERiPTHR22504. PTHR22504. 1 hit.
PfamiPF09174. Maf1. 1 hit.
[Graphical view]
PIRSFiPIRSF037240. RNA_polIII_Trep_MAF1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6PGU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLENSSFE AINSLLTIET GDCKIIGRIE SYSCKMAGDD KQMFKQFCQE
60 70 80 90 100
GQPHVLEALS PPQSSGISPN KLSHSLDDGE GPLSDKCSRK TLFYLIATLN
110 120 130 140 150
ESFRPDYDFS RTKGHDFSKE PSVNWVFNAV NSSLSAAAGE AYSHLQPQLW
160 170 180 190 200
EALDKEISLA ECDIYSYNPD LDSDPYGEEG NLWSFNYFFY NKRLKRIVFF
210 220 230 240
TCRSVSLFMA PRDSGIGTEL DLELDEGSYE EEEEGNMDEE RYGALCA
Length:247
Mass (Da):27,874
Last modified:July 5, 2004 - v1
Checksum:i7C05622ABEE6887B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC056831 mRNA. Translation: AAH56831.1.
RefSeqiNP_998606.1. NM_213441.1.
UniGeneiDr.77656.

Genome annotation databases

EnsembliENSDART00000006703; ENSDARP00000015577; ENSDARG00000013122.
GeneIDi406750.
KEGGidre:406750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC056831 mRNA. Translation: AAH56831.1.
RefSeqiNP_998606.1. NM_213441.1.
UniGeneiDr.77656.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015577.

Proteomic databases

PaxDbiQ6PGU2.

Protocols and materials databases

DNASUi406750.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000006703; ENSDARP00000015577; ENSDARG00000013122.
GeneIDi406750.
KEGGidre:406750.

Organism-specific databases

CTDi84232.
ZFINiZDB-GENE-040426-2788. maf1.

Phylogenomic databases

eggNOGiKOG3104. Eukaryota.
COG5046. LUCA.
GeneTreeiENSGT00390000006896.
HOGENOMiHOG000185242.
HOVERGENiHBG052395.
InParanoidiQ6PGU2.
OMAiGNLWSFN.
OrthoDBiEOG776SQX.
PhylomeDBiQ6PGU2.
TreeFamiTF315149.

Miscellaneous databases

PROiQ6PGU2.

Gene expression databases

BgeeiQ6PGU2.

Family and domain databases

InterProiIPR015257. Maf1.
[Graphical view]
PANTHERiPTHR22504. PTHR22504. 1 hit.
PfamiPF09174. Maf1. 1 hit.
[Graphical view]
PIRSFiPIRSF037240. RNA_polIII_Trep_MAF1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: AB.

Entry informationi

Entry nameiMAF1_DANRE
AccessioniPrimary (citable) accession number: Q6PGU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 5, 2004
Last modified: June 8, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.