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Unreviewed, UniProtKB/TrEMBL Q6PF82 (Q6PF82_MOUSE)

Last modified January 19, 2010. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Prkcz protein EMBL AAH57694.1
Gene names
Name: Prkcz MGI 97602
OrganismMus musculus (Mouse) EMBL AAH57694.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length316 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein. Spearmint SPM000961

Sequence similarities

Contains 1 AGC-kinase C-terminal domain.

Contains 1 protein kinase domain.

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Ontologies

Keywords
   LigandATP-binding Spearmint SPM000961
Nucleotide-binding
   Molecular functionKinase
Serine/threonine-protein kinase Spearmint SPM000961
Transferase
Gene Ontology (GO)
   Biological processactin cytoskeleton reorganization

Inferred from electronic annotation. Source: Compara

activation of phospholipase D activity

Inferred from electronic annotation. Source: Compara

activation of protein kinase B activity

Inferred from electronic annotation. Source: Compara

insulin receptor signaling pathway

Inferred from electronic annotation. Source: Compara

long-term memory

Inferred from electronic annotation. Source: Compara

membrane depolarization

Inferred from electronic annotation. Source: Compara

membrane hyperpolarization

Inferred from electronic annotation. Source: Compara

negative regulation of apoptosis

Inferred from electronic annotation. Source: Compara

negative regulation of hydrolase activity

Inferred from electronic annotation. Source: Compara

negative regulation of insulin receptor signaling pathway

Inferred from electronic annotation. Source: Compara

negative regulation of peptidyl-tyrosine phosphorylation

Inferred from electronic annotation. Source: Compara

negative regulation of protein complex assembly

Inferred from electronic annotation. Source: Compara

peptidyl-serine phosphorylation

Inferred from electronic annotation. Source: Compara

positive regulation of cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of cell-matrix adhesion

Inferred from electronic annotation. Source: Compara

positive regulation of glucose import

Inferred from electronic annotation. Source: Compara

positive regulation of protein transport

Inferred from electronic annotation. Source: Compara

positive regulation of synaptic transmission

Inferred from electronic annotation. Source: Compara

protein heterooligomerization

Inferred from electronic annotation. Source: Compara

vesicle transport along microtubule

Inferred from electronic annotation. Source: Compara

   Cellular componentcytosol

Inferred from electronic annotation. Source: Compara

filamentous actin

Inferred from electronic annotation. Source: Compara

membrane raft

Inferred from electronic annotation. Source: Compara

microsome

Inferred from electronic annotation. Source: Compara

perinuclear region of cytoplasm

Inferred from electronic annotation. Source: Compara

plasma membrane

Inferred from electronic annotation. Source: Compara

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phospholipase binding

Inferred from electronic annotation. Source: Compara

potassium channel regulator activity

Inferred from electronic annotation. Source: Compara

protein kinase binding

Inferred from electronic annotation. Source: Compara

protein serine/threonine kinase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAH57694.1

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Sequences

Sequence LengthMass (Da)Tools
Q6PF82-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: BF79A9CDD03D4475

FASTA31636,407
        10         20         30         40         50         60 
IYAMKVVKKE LVHDDEDIDW VQTEKHVFEQ ASSNPFLVGL HSCFQTTSRL FLVIEYVNGG 

        70         80         90        100        110        120 
DLMFHMQRQR KLPEEHARFY AAEICIALNF LHERGIIYRD LKLDNVLLDA DGHIKLTDYG 

       130        140        150        160        170        180 
MCKEGLGPGD TTSTFCGTPN YIAPEILRGE EYGFSVDWWA LGVLMFEMMA GRSPFDIITD 

       190        200        210        220        230        240 
NPDMNTEDYL FQVILEKPIR IPRFLSVKAS HVLKGFLNKD PKERLGCRPQ TGFSDIKSHA 

       250        260        270        280        290        300 
FFRSIDWDLL EKKQTLPPFQ PQITDDYGLD NFDTQFTSEP VQLTPDDEDV IKRIDQSEFE 

       310 
GFEYINPLLL SAEESV

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References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye EMBL AAH57694.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC057694 mRNA. Translation: AAH57694.1.
IPIIPI00648131.
UniGeneMm.28561

3D structure databases

HSSPHSSP built from PDB template 1APM based on UniProtKB P05132.
SMRQ6PF82. Positions 1-308.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6PF82.

Genome annotation databases

EnsemblENSMUST00000030922; ENSMUSP00000030922; ENSMUSG00000029053; Mus musculus. [Genome view]
ENSMUST00000103178; ENSMUSP00000099467; ENSMUSG00000029053; Mus musculus. [Genome view]

Organism-specific databases

MGIMGI:97602. Prkcz.

Phylogenomic databases

HOVERGENQ6PF82.
InParanoidQ6PF82.

Gene expression databases

ArrayExpressQ6PF82.
BgeeQ6PF82.
GenevestigatorQ6PF82.

Family and domain databases

InterProIPR000961. AGC-kinase_C.
IPR011009. Kinase-like_dom.
IPR015745. PKC.
IPR017892. Pkinase_C.
IPR000719. Prot_kinase_cat_dom.
IPR017442. Se/Thr_prot_kinase-like_dom.
IPR008271. Ser/Thr_prot_kinase_AS.
IPR002290. Ser/Thr_prot_kinase_dom.
[Graphical view]
PANTHERPTHR22985:SF86. PKC. 1 hit.
PfamPF00069. Pkinase. 1 hit.
PF00433. Pkinase_C. 1 hit.
[Graphical view]
SMARTSM00133. S_TK_X. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
PROSITEPS51285. AGC_KINASE_CTER. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

SOURCESearch...

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Entry information

Entry nameQ6PF82_MOUSE
AccessionPrimary (citable) accession number: Q6PF82
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 19, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information