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Q6PF18

- MORN3_HUMAN

UniProt

Q6PF18 - MORN3_HUMAN

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Protein

MORN repeat-containing protein 3

Gene

MORN3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
MORN repeat-containing protein 3
Gene namesi
Name:MORN3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 12

Organism-specific databases

HGNCiHGNC:29807. MORN3.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProt
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA143485546.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 240240MORN repeat-containing protein 3PRO_0000247459Add
BLAST

Proteomic databases

PaxDbiQ6PF18.
PRIDEiQ6PF18.

PTM databases

PhosphoSiteiQ6PF18.

Expressioni

Gene expression databases

BgeeiQ6PF18.
CleanExiHS_MORN3.
GenevestigatoriQ6PF18.

Organism-specific databases

HPAiHPA038709.
HPA038710.

Interactioni

Protein-protein interaction databases

IntActiQ6PF18. 1 interaction.
STRINGi9606.ENSP00000347486.

Structurei

3D structure databases

ProteinModelPortaliQ6PF18.
SMRiQ6PF18. Positions 12-99, 136-194.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati38 – 6023MORN 1Add
BLAST
Repeati62 – 8423MORN 2Add
BLAST
Repeati91 – 11323MORN 3Add
BLAST
Repeati114 – 13623MORN 4Add
BLAST
Repeati137 – 15923MORN 5Add
BLAST
Repeati160 – 18223MORN 6Add
BLAST
Repeati184 – 20522MORN 7Add
BLAST

Sequence similaritiesi

Contains 7 MORN repeats.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG4642.
GeneTreeiENSGT00730000110297.
HOGENOMiHOG000007397.
HOVERGENiHBG067658.
InParanoidiQ6PF18.
OMAiYEGCWER.
OrthoDBiEOG7CCBS3.
PhylomeDBiQ6PF18.
TreeFamiTF323893.

Family and domain databases

InterProiIPR003409. MORN.
[Graphical view]
PfamiPF02493. MORN. 5 hits.
[Graphical view]
SMARTiSM00698. MORN. 6 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6PF18-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPVSKCPKKS ESLWKGWDRK AQRNGLRSQV YAVNGDYYVG EWKDNVKHGK
60 70 80 90 100
GTQVWKKKGA IYEGDWKFGK RDGYGTLSLP DQQTGKCRRV YSGWWKGDKK
110 120 130 140 150
SGYGIQFFGP KEYYEGDWCG SQRSGWGRMY YSNGDIYEGQ WENDKPNGEG
160 170 180 190 200
MLRLKNGNRY EGCWERGMKN GAGRFFHLDH GQLFEGFWVD NMAKCGTMID
210 220 230 240
FGRDEAPEPT QFPIPEVKIL DPDGVLAEAL AMFRKTEEGD
Length:240
Mass (Da):27,585
Last modified:May 18, 2010 - v2
Checksum:i8B87C00C47203D55
GO
Isoform 2 (identifier: Q6PF18-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     155-160: KNGNRY → SQNPRP
     161-240: Missing.

Show »
Length:160
Mass (Da):18,546
Checksum:iC756381DBD39E318
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti43 – 431K → E in AAH57760. (PubMed:15489334)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei155 – 1606KNGNRY → SQNPRP in isoform 2. 1 PublicationVSP_019996
Alternative sequencei161 – 24080Missing in isoform 2. 1 PublicationVSP_019997Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY177732 mRNA. Translation: AAO18675.1.
AC084018 Genomic DNA. No translation available.
AC140062 Genomic DNA. No translation available.
BC057760 mRNA. Translation: AAH57760.1.
CCDSiCCDS31917.1. [Q6PF18-1]
RefSeqiNP_776254.3. NM_173855.4. [Q6PF18-1]
XP_005253926.1. XM_005253869.2. [Q6PF18-1]
UniGeneiHs.434154.

Genome annotation databases

EnsembliENST00000355329; ENSP00000347486; ENSG00000139714. [Q6PF18-1]
ENST00000392462; ENSP00000376255; ENSG00000139714. [Q6PF18-2]
ENST00000542364; ENSP00000445643; ENSG00000139714. [Q6PF18-2]
GeneIDi283385.
KEGGihsa:283385.
UCSCiuc001uax.3. human. [Q6PF18-1]

Polymorphism databases

DMDMi296438295.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY177732 mRNA. Translation: AAO18675.1 .
AC084018 Genomic DNA. No translation available.
AC140062 Genomic DNA. No translation available.
BC057760 mRNA. Translation: AAH57760.1 .
CCDSi CCDS31917.1. [Q6PF18-1 ]
RefSeqi NP_776254.3. NM_173855.4. [Q6PF18-1 ]
XP_005253926.1. XM_005253869.2. [Q6PF18-1 ]
UniGenei Hs.434154.

3D structure databases

ProteinModelPortali Q6PF18.
SMRi Q6PF18. Positions 12-99, 136-194.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q6PF18. 1 interaction.
STRINGi 9606.ENSP00000347486.

PTM databases

PhosphoSitei Q6PF18.

Polymorphism databases

DMDMi 296438295.

Proteomic databases

PaxDbi Q6PF18.
PRIDEi Q6PF18.

Protocols and materials databases

DNASUi 283385.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000355329 ; ENSP00000347486 ; ENSG00000139714 . [Q6PF18-1 ]
ENST00000392462 ; ENSP00000376255 ; ENSG00000139714 . [Q6PF18-2 ]
ENST00000542364 ; ENSP00000445643 ; ENSG00000139714 . [Q6PF18-2 ]
GeneIDi 283385.
KEGGi hsa:283385.
UCSCi uc001uax.3. human. [Q6PF18-1 ]

Organism-specific databases

CTDi 283385.
GeneCardsi GC12M122089.
HGNCi HGNC:29807. MORN3.
HPAi HPA038709.
HPA038710.
neXtProti NX_Q6PF18.
PharmGKBi PA143485546.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG4642.
GeneTreei ENSGT00730000110297.
HOGENOMi HOG000007397.
HOVERGENi HBG067658.
InParanoidi Q6PF18.
OMAi YEGCWER.
OrthoDBi EOG7CCBS3.
PhylomeDBi Q6PF18.
TreeFami TF323893.

Miscellaneous databases

ChiTaRSi MORN3. human.
GenomeRNAii 283385.
NextBioi 93859.
PROi Q6PF18.

Gene expression databases

Bgeei Q6PF18.
CleanExi HS_MORN3.
Genevestigatori Q6PF18.

Family and domain databases

InterProi IPR003409. MORN.
[Graphical view ]
Pfami PF02493. MORN. 5 hits.
[Graphical view ]
SMARTi SM00698. MORN. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Mao Y., Xie Y., Wu H.
    Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
  2. "The finished DNA sequence of human chromosome 12."
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Placenta.

Entry informationi

Entry nameiMORN3_HUMAN
AccessioniPrimary (citable) accession number: Q6PF18
Secondary accession number(s): Q86YQ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: May 18, 2010
Last modified: November 26, 2014
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3