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Protein
Submitted name:

Calr protein

Gene

calr3a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei109CarbohydrateUniRule annotation1
Binding sitei111CarbohydrateUniRule annotation1
Binding sitei128CarbohydrateUniRule annotation1
Binding sitei135CarbohydrateUniRule annotation1
Binding sitei317CarbohydrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Calr proteinImported
Submitted name:
Calreticulin 3aImported
Gene namesi
Name:calr3aImported
Synonyms:calrImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 22

Organism-specific databases

ZFINiZDB-GENE-000208-17. calr3a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19UniRule annotationAdd BLAST19
ChainiPRO_501075480320 – 418UniRule annotationAdd BLAST399

Expressioni

Gene expression databases

BgeeiENSDARG00000103979.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000063524.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili354 – 387Sequence analysisAdd BLAST34

Sequence similaritiesi

Belongs to the calreticulin family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG0674. Eukaryota.
ENOG410XRR7. LUCA.
GeneTreeiENSGT00430000030841.
HOVERGENiHBG005407.
KOiK08057.
TreeFamiTF338438.

Family and domain databases

InterProiView protein in InterPro
IPR001580. Calret/calnex.
IPR018124. Calret/calnex_CS.
IPR009169. Calreticulin.
IPR009033. Calreticulin/calnexin_P_dom.
IPR013320. ConA-like_dom.
PANTHERiPTHR11073. PTHR11073. 1 hit.
PfamiView protein in Pfam
PF00262. Calreticulin. 2 hits.
PIRSFiPIRSF002356. Calreticulin. 1 hit.
PRINTSiPR00626. CALRETICULIN.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF63887. SSF63887. 1 hit.
PROSITEiView protein in PROSITE
PS00803. CALRETICULIN_1. 1 hit.
PS00804. CALRETICULIN_2. 1 hit.
PS00805. CALRETICULIN_REPEAT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6PE26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRITAAVCFI SALAFIAHAD VYFKEQFLDG DGWKSRWVES KHKSDYGQWK
60 70 80 90 100
LTSGKFYGDA ELDKGLQTSQ DARFYALSSR FDSFSNEGKT LVIQFTVKHE
110 120 130 140 150
QKIDCGGGYV KVFPAEMDQT EMHGESQYYI MFGPDICGYS TKKVHVIFNY
160 170 180 190 200
KGQNHLIKKD IKCKDDELTH LYTLILRPDQ TYEVKIDNEK VESGSLEEDW
210 220 230 240 250
DFLPPKKIKD PEAKKPDDWD DRAKIDDPED TKPEDWDKPE NIPDPDAKKP
260 270 280 290 300
DDWDEDMDGE WEPAMIPNPE YKGEWKPKQI DNPSYKGTWV HPEIDNPEYA
310 320 330 340 350
ADDAIYKFDS IGVLGLDLWQ VKSGTIFDNF LITDDVEEAE KFGTDTWGAT
360 370 380 390 400
KGPEKKMKDQ QEEEERKKRE EEEKSKKDDN EEDEEDEDED EPEEDDHTEE
410
PPEEEEEGED DALPKDEL
Length:418
Mass (Da):48,540
Last modified:July 5, 2004 - v1
Checksum:i10D092CC380C7071
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR751224 Genomic DNA. No translation available.
CU570881 Genomic DNA. No translation available.
BC058314 mRNA. Translation: AAH58314.1.
RefSeqiNP_571122.2. NM_131047.2.
UniGeneiDr.104606.

Genome annotation databases

EnsembliENSDART00000165235; ENSDARP00000130666; ENSDARG00000103979.
GeneIDi30248.
KEGGidre:30248.

Similar proteinsi

Entry informationi

Entry nameiQ6PE26_DANRE
AccessioniPrimary (citable) accession number: Q6PE26
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported