Reviewed, UniProtKB/Swiss-Prot Q6PE25 (EF1G_DANRE)

Names and origin

Protein names

Recommended name:
    Elongation factor 1-gamma
      Short name=EF-1-gamma
Alternative name(s):
    eEF-1B gamma

Gene names

Name:

eef1g

Organism

Danio rerio (Zebrafish) (Brachydanio rerio)

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	442 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: InterPro
Cellular component	eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 442	442	Elongation factor 1-gamma		PRO_0000208818
Regions
	Domain	2 – 87	86	GST N-terminal
	Domain	88 – 216	129	GST C-terminal
	Domain	281 – 442	162	EF-1-gamma C-terminal

Sequences

	Sequence		Length	Mass (Da)
	Q6PE25-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 649D14FBEC848BF3	FASTA	442	50,457
	10 20 30 40 50 60 MAAGTLYTYP ENWRAFKAQI AAQYSGARLK IASAPPAFTF GQTNRSPAFL GNFPLGKVPA 70 80 90 100 110 120 YQGDDGFCLF ESNAIAHYLS NDVLRGSTPQ ASAQVLQWVS FADSEVIPPA SAWVFPTLGI 130 140 150 160 170 180 MQFNKQATEQ AKEEVKRVLA VLNQHLNTRT FLVGERISLA DITVVCSLLW LYKQVLEPAF 190 200 210 220 230 240 RQPYPNVTRW FVTCVNQPQF KTVLGEVKLC EKMAQFDAKK FAEMQPKKEA PIKKEKGGKE 250 260 270 280 290 300 GGKQQPQQQE KKEKKKEEKK AAPAEEEMDE CEAALASEPK AKDPFAHLPK SSFVMDEFKR 310 320 330 340 350 360 KYSNEDTMTV ALPYFWDHFD REGFSIWYAE YRFPEELTMA FMSCNLITGM FQRLDKLRKN 370 380 390 400 410 420 AFASVILFGA NNDSCISGIW VFRGQDLAFP LSDDWQIDYE SYTWRKLDVD SEECKTMVKE 430 440 YFAWEGEFKH VGKPFNQGKI FK

References

[1]	"Hematopoietic gene expression profile in zebrafish kidney marrow." Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y., Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X., Look A.T., Chen Z. Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004) [PubMed: 15520368] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney marrow.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AY394968 mRNA. Translation: AAQ94595.1. BC058315 mRNA. Translation: AAH58315.1.
IPI	IPI00494173.
UniGene	Dr.75657
3D structure databases
SMR	Q6PE25. Positions 281-442.
ModBase	Search...
Proteomic databases
PRIDE	Q6PE25.
Genome annotation databases
Ensembl	ENSDARG00000056119. Danio rerio. [Contig view]
NMPDR	fig|7955.3.peg.5332.
Organism-specific databases
ZFIN	ZDB-GENE-020423-3. eef1g.
Phylogenomic databases
HOGENOM	Q6PE25.
HOVERGEN	Q6PE25.
OMA	Q6PE25. KSIPYFW.
Gene expression databases
ArrayExpress	Q6PE25.
Bgee	Q6PE25.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
ProDom	PD006217. EF1_G. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G_DANRE

Accession

Primary (citable) accession number: Q6PE25

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 9, 2004
Last sequence update:	July 5, 2004
Last modified:	June 16, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Zebrafish annotation project