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Q6PE25 (EF1G_DANRE) Reviewed, UniProtKB/Swiss-Prot

Last modified September 21, 2011. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor 1-gamma
Short name=EF-1-gamma
Alternative name(s):
eEF-1B gamma
Gene names
Name:eef1g
OrganismDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length442 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probably plays a role in anchoring the complex to other cellular components.

Subunit structure

EF-1 is composed of four subunits: alpha, beta, delta, and gamma.

Sequence similarities

Contains 1 EF-1-gamma C-terminal domain.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Molecular functionElongation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componenteukaryotic translation elongation factor 1 complex

Inferred from electronic annotation. Source: InterPro

   Molecular functiontranslation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 442442Elongation factor 1-gamma
PRO_0000208818

Regions

Domain2 – 8786GST N-terminal
Domain88 – 216129GST C-terminal
Domain281 – 442162EF-1-gamma C-terminal

Sequences

Sequence LengthMass (Da)Tools
Q6PE25 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 649D14FBEC848BF3

FASTA44250,457
        10         20         30         40         50         60 
MAAGTLYTYP ENWRAFKAQI AAQYSGARLK IASAPPAFTF GQTNRSPAFL GNFPLGKVPA 

        70         80         90        100        110        120 
YQGDDGFCLF ESNAIAHYLS NDVLRGSTPQ ASAQVLQWVS FADSEVIPPA SAWVFPTLGI 

       130        140        150        160        170        180 
MQFNKQATEQ AKEEVKRVLA VLNQHLNTRT FLVGERISLA DITVVCSLLW LYKQVLEPAF 

       190        200        210        220        230        240 
RQPYPNVTRW FVTCVNQPQF KTVLGEVKLC EKMAQFDAKK FAEMQPKKEA PIKKEKGGKE 

       250        260        270        280        290        300 
GGKQQPQQQE KKEKKKEEKK AAPAEEEMDE CEAALASEPK AKDPFAHLPK SSFVMDEFKR 

       310        320        330        340        350        360 
KYSNEDTMTV ALPYFWDHFD REGFSIWYAE YRFPEELTMA FMSCNLITGM FQRLDKLRKN 

       370        380        390        400        410        420 
AFASVILFGA NNDSCISGIW VFRGQDLAFP LSDDWQIDYE SYTWRKLDVD SEECKTMVKE 

       430        440 
YFAWEGEFKH VGKPFNQGKI FK

« Hide

References

[1]"Hematopoietic gene expression profile in zebrafish kidney marrow."
Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y., Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X., Look A.T., Chen Z.
Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004) [PubMed: 15520368] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney marrow.
[2]NIH - Zebrafish Gene Collection (ZGC) project
Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Kidney.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY394968 mRNA. Translation: AAQ94595.1.
BC058315 mRNA. Translation: AAH58315.1.
IPIIPI00972523.
UniGeneDr.75657.

3D structure databases

ProteinModelPortalQ6PE25.
SMRQ6PE25. Positions 281-442.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6PE25.

Proteomic databases

PRIDEQ6PE25.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSDART00000078522; ENSDARP00000072983; ENSDARG00000056119.
NMPDRfig|7955.3.peg.5332.

Organism-specific databases

ZFINZDB-GENE-020423-3. eef1g.

Phylogenomic databases

HOGENOMHBG436026.
HOVERGENHBG051444.
InParanoidQ6PE25.
OMAGFCLFES.
OrthoDBEOG43JC4V.
PhylomeDBQ6PE25.

Gene expression databases

ArrayExpressQ6PE25.
BgeeQ6PE25.

Family and domain databases

InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR017933. Glutathione_S_Trfase/Cl_chnl_C.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
IPR001662. Transl_elong_EF1_G_con.
[Graphical view]
Gene3DG3DSA:1.20.1050.10. GST_C_like. 1 hit.
G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
PfamPF00647. EF1G. 1 hit.
PF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. GST_C_like. 1 hit.
SSF52833. Thiordxn-like_fd. 1 hit.
SSF89942. Transl_elong_EF1_G_con. 1 hit.
PROSITEPS50040. EF1G_C. 1 hit.
PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEF1G_DANRE
AccessionPrimary (citable) accession number: Q6PE25
Entry history
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: July 5, 2004
Last modified: September 21, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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