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Protein

Tumor protein D54

Gene

Tpd52l2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Tumor protein D54
Alternative name(s):
Tumor protein D52-like 2
Gene namesi
Name:Tpd52l2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi735167. Tpd52l2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 220220Tumor protein D54PRO_0000185747Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity
Modified residuei3 – 31PhosphoserineBy similarity
Modified residuei12 – 121PhosphoserineCombined sources
Modified residuei19 – 191PhosphoserineBy similarity
Modified residuei96 – 961PhosphoserineBy similarity
Modified residuei149 – 1491PhosphoserineBy similarity
Modified residuei168 – 1681PhosphoserineBy similarity
Modified residuei175 – 1751PhosphoserineBy similarity
Modified residuei177 – 1771PhosphothreonineBy similarity
Modified residuei180 – 1801PhosphoserineCombined sources
Modified residuei187 – 1871PhosphothreonineBy similarity
Modified residuei206 – 2061PhosphoserineBy similarity
Modified residuei209 – 2091PhosphoserineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ6PCT3.
PRIDEiQ6PCT3.

PTM databases

iPTMnetiQ6PCT3.
PhosphoSiteiQ6PCT3.

Expressioni

Gene expression databases

BgeeiENSRNOG00000015122.
GenevisibleiQ6PCT3. RN.

Interactioni

Subunit structurei

Forms a homodimer or heterodimer with other members of the family. Interacts with MAL2 (By similarity).By similarity

Protein-protein interaction databases

BioGridi255374. 1 interaction.
STRINGi10116.ENSRNOP00000020374.

Structurei

3D structure databases

ProteinModelPortaliQ6PCT3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili40 – 8243Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TPD52 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4010. Eukaryota.
ENOG4111M9H. LUCA.
GeneTreeiENSGT00390000015988.
HOGENOMiHOG000231968.
HOVERGENiHBG058643.
InParanoidiQ6PCT3.
OMAiRARPFSH.
OrthoDBiEOG091G0MLN.
PhylomeDBiQ6PCT3.

Family and domain databases

InterProiIPR007327. TPD52.
[Graphical view]
PANTHERiPTHR19307. PTHR19307. 1 hit.
PfamiPF04201. TPD52. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PCT3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSASQDINL NSPNKGVLSD FMTDVPVDPG VVHRTPAVEG LTEVEEEELR
60 70 80 90 100
AELAKVEEEI VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV
110 120 130 140 150
QGSTAYVKTS EKLGEWNEKV TQSDLYKKTQ ETLSQAGQKT SAALSTMGSA
160 170 180 190 200
ISRKLGDMSS YSIRHSISMP VMRNSATFKS FEDRVGTIKS KVVGGRENGS
210 220
DTLPSSPGSG DQTLPDHAPF
Length:220
Mass (Da):23,992
Last modified:July 5, 2004 - v1
Checksum:i505408FBFFABAFD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC059167 mRNA. Translation: AAH59167.1.
RefSeqiNP_942039.1. NM_198744.2.
UniGeneiRn.1207.
Rn.234320.

Genome annotation databases

EnsembliENSRNOT00000020373; ENSRNOP00000020374; ENSRNOG00000015122.
GeneIDi296480.
KEGGirno:296480.
UCSCiRGD:735167. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC059167 mRNA. Translation: AAH59167.1.
RefSeqiNP_942039.1. NM_198744.2.
UniGeneiRn.1207.
Rn.234320.

3D structure databases

ProteinModelPortaliQ6PCT3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi255374. 1 interaction.
STRINGi10116.ENSRNOP00000020374.

PTM databases

iPTMnetiQ6PCT3.
PhosphoSiteiQ6PCT3.

Proteomic databases

PaxDbiQ6PCT3.
PRIDEiQ6PCT3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000020373; ENSRNOP00000020374; ENSRNOG00000015122.
GeneIDi296480.
KEGGirno:296480.
UCSCiRGD:735167. rat.

Organism-specific databases

CTDi7165.
RGDi735167. Tpd52l2.

Phylogenomic databases

eggNOGiKOG4010. Eukaryota.
ENOG4111M9H. LUCA.
GeneTreeiENSGT00390000015988.
HOGENOMiHOG000231968.
HOVERGENiHBG058643.
InParanoidiQ6PCT3.
OMAiRARPFSH.
OrthoDBiEOG091G0MLN.
PhylomeDBiQ6PCT3.

Miscellaneous databases

PROiQ6PCT3.

Gene expression databases

BgeeiENSRNOG00000015122.
GenevisibleiQ6PCT3. RN.

Family and domain databases

InterProiIPR007327. TPD52.
[Graphical view]
PANTHERiPTHR19307. PTHR19307. 1 hit.
PfamiPF04201. TPD52. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTPD54_RAT
AccessioniPrimary (citable) accession number: Q6PCT3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.