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Protein
Submitted name:

Protein Zbtb40

Gene

Zbtb40

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro

GO - Biological processi

  1. cellular response to DNA damage stimulus Source: UniProtKB
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Zbtb40Imported
Submitted name:
Zinc finger and BTB domain containing 40Imported
Gene namesi
Name:Zbtb40Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:2682254. Zbtb40.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriQ6PCS8.

Family & Domainsi

Sequence similaritiesi

Contains 1 BTB (POZ) domain.UniRule annotation

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00740000115612.
HOGENOMiHOG000143421.
HOVERGENiHBG058697.
KOiK10512.
OMAiCVTQLRP.
OrthoDBiEOG7BGHJW.
TreeFamiTF350897.

Family and domain databases

Gene3Di3.30.160.60. 7 hits.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR030404. ZBTB40.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24394:SF0. PTHR24394:SF0. 1 hit.
PfamiPF00651. BTB. 1 hit.
PF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 11 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PCS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELPSYSQQL LLQLYALCKE QRFCDCTISV GNIYFRAHKP VLAAASLLFK
60 70 80 90 100
TLLDSTDAIS IDASVVSPEE FALLLEMTYT GKLPVGKHNF SKIISLADSL
110 120 130 140 150
QMFDVAVSCK NLLTNLVNCS VQGQVVRDVS VLSSEAGNKE SEKPQVEALS
160 170 180 190 200
SEGAEEPSSS PEVSAVPAGP EKAKTQDVIN IATQEINADP PVAQEVQVAA
210 220 230 240 250
EITGATPHTA EVCSPSPVGQ IPSETKEVNT EAECETKQDQ LTLLLEHESV
260 270 280 290 300
FSDAALLTPD TLRRLAGCSE IEGPQKETII ECLTSEGGSS AFQRILDKVH
310 320 330 340 350
DGSLDVQVAL SLVRLYQEST PAEKVSQIQP EGSAGEGKTL SVLLLEHKED
360 370 380 390 400
LIQCVTQLRP IVEFLETAKE EFLPDSEKRV IQSCCEGRTP KEMIENLLHR
410 420 430 440 450
VTEEKTLPAK SLVKLLQAVR TAFPNLDLLL DNLQKGAGSA GTTGLARVSC
460 470 480 490 500
ESEWTDEPRP VCIPADRVDG SSPSPDAYGA ELLRKYHENL SEILIDNQVL
510 520 530 540 550
LKVISRMQSL APGDREVMQT LVKQGSGSGG FSSLMLAALE RQTLSATAIW
560 570 580 590 600
QLLLAVEETE TRPLNLLLEE VGKEPGAGAF FRAVTAPEST VLEAILRHSK
610 620 630 640 650
LLREAIQQTA GCERLSSEEE HLAETVQEML SISSETVSPE ASLRAVLSKA
660 670 680 690 700
MEKSVSASVV CHLLCSVHKS FPGLQPLMQE LAHVGFLTKE SGEERWKVTD
710 720 730 740 750
GLHPGAKDKV EEVAKATGED CQANEQKEQG EPGPVPEQPE KDTSASPDSA
760 770 780 790 800
KKSFVCKACD KSFHFYCRLK VHMKRCRVAK SRQVQSEEGS ETKGSEKGLE
810 820 830 840 850
KQQPDARGTG GEPDAPKKKK KRLPVTCDLC GREFAHASGM QYHKLTEHFD
860 870 880 890 900
EKPFSCEECG AKFAANSTLK NHLRLHTGDR PFMCKHCLMT FTQASALAYH
910 920 930 940 950
TKKKHSEGKM YACQYCDAVF AQSIELSRHV RTHTGDKPYV CRDCGKGFRQ
960 970 980 990 1000
ANGLSIHLHT FHTDIEDPYD CKKCRMSFST LQDHRKHIHE VHAKEYHPCP
1010 1020 1030 1040 1050
TCGKIFSAPS MLERHMVTHV GGKPFSCGIC NKAYQQLSGL WYHNRTHHPD
1060 1070 1080 1090 1100
VFAAQNHRSP KFSSLQCSSC DKTFSNTVEH KKHIKTEHTD VKFHECDQCK
1110 1120 1130 1140 1150
ELFPTPALLQ VHVKCQHSGS QPFRCLYCAA TFRFPGALQH HVTTEHFKQS
1160 1170 1180 1190 1200
ESTFPCELCG ELFTSQAQLD SHLESEHPKV AGTESQAAAS RMVQVIRAPE
1210 1220 1230 1240 1250
PAAPAEQVIT LEETQLAGSQ VFVTLPDSQT SQNSSELVAV TVEDLLDGTV

TLICGEAK
Length:1,258
Mass (Da):138,167
Last modified:July 5, 2004 - v1
Checksum:i469EA921CEE4B821
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL627214 Genomic DNA. No translation available.
AL671011 Genomic DNA. No translation available.
BC059177 mRNA. Translation: AAH59177.1.
RefSeqiNP_937891.1. NM_198248.1.
UniGeneiMm.31068.

Genome annotation databases

EnsembliENSMUST00000049583; ENSMUSP00000061899; ENSMUSG00000060862.
GeneIDi230848.
KEGGimmu:230848.
UCSCiuc008vit.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL627214 Genomic DNA. No translation available.
AL671011 Genomic DNA. No translation available.
BC059177 mRNA. Translation: AAH59177.1.
RefSeqiNP_937891.1. NM_198248.1.
UniGeneiMm.31068.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000049583; ENSMUSP00000061899; ENSMUSG00000060862.
GeneIDi230848.
KEGGimmu:230848.
UCSCiuc008vit.1. mouse.

Organism-specific databases

CTDi9923.
MGIiMGI:2682254. Zbtb40.

Phylogenomic databases

GeneTreeiENSGT00740000115612.
HOGENOMiHOG000143421.
HOVERGENiHBG058697.
KOiK10512.
OMAiCVTQLRP.
OrthoDBiEOG7BGHJW.
TreeFamiTF350897.

Miscellaneous databases

NextBioi380210.
PROiQ6PCS8.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ6PCS8.

Family and domain databases

Gene3Di3.30.160.60. 7 hits.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR030404. ZBTB40.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24394:SF0. PTHR24394:SF0. 1 hit.
PfamiPF00651. BTB. 1 hit.
PF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00225. BTB. 1 hit.
SM00355. ZnF_C2H2. 13 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 12 hits.
PS50157. ZINC_FINGER_C2H2_2. 11 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6Imported.
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ6PCS8_MOUSE
AccessioniPrimary (citable) accession number: Q6PCS8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 4, 2015
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.