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Protein

40S ribosomal protein S12

Gene

rps12

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationImported

Enzyme and pathway databases

ReactomeiR-DRE-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DRE-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DRE-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-DRE-72649 Translation initiation complex formation
R-DRE-72689 Formation of a pool of free 40S subunits
R-DRE-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-DRE-72702 Ribosomal scanning and start codon recognition
R-DRE-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DRE-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DRE-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S12UniRule annotation
Gene namesi
Name:rps12Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 23

Organism-specific databases

ZFINiZDB-GENE-030131-8951 rps12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000036875

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000053541

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 110Ribosomal_L7AeInterPro annotationAdd BLAST94

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eS12 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3406 Eukaryota
COG1358 LUCA
GeneTreeiENSGT00390000018318
HOGENOMiHOG000210688
HOVERGENiHBG001720
KOiK02951
OMAiGLRECAK
OrthoDBiEOG091G0UB5
TreeFamiTF300196

Family and domain databases

Gene3Di3.30.1330.30, 1 hit
InterProiView protein in InterPro
IPR029064 L30e-like
IPR004038 Ribosomal_L7Ae/L30e/S12e/Gad45
IPR000530 Ribosomal_S12e
PANTHERiPTHR11843 PTHR11843, 1 hit
PfamiView protein in Pfam
PF01248 Ribosomal_L7Ae, 1 hit
PRINTSiPR00972 RIBSOMALS12E
SUPFAMiSSF55315 SSF55315, 1 hit
PROSITEiView protein in PROSITE
PS01189 RIBOSOMAL_S12E, 1 hit

Sequencei

Sequence statusi: Complete.

Q6PC90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEGIAAGG VMDVNTALPE VLKTALIHDG LARGIREAAK ALDKRQAHLC
60 70 80 90 100
VLAANCDEPM YVKLVEALCA EHQINLIKVD DNKKLGEWVG LCKIDREGKP
110 120 130
RKVVGCSCVV IKDYGKESQA KDVIEEYFKS KK
Length:132
Mass (Da):14,466
Last modified:July 5, 2004 - v1
Checksum:iF453D1888392ED8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR759830 Genomic DNA No translation available.
BC059433 mRNA Translation: AAH59433.1
AY561510 mRNA Translation: AAS66963.1
RefSeqiNP_001269106.1, NM_001282177.1
NP_956340.1, NM_200046.3
UniGeneiDr.75550

Genome annotation databases

EnsembliENSDART00000053542; ENSDARP00000053541; ENSDARG00000036875
ENSDART00000138350; ENSDARP00000120403; ENSDARG00000036875
GeneIDi337007
KEGGidre:337007

Similar proteinsi

Entry informationi

Entry nameiQ6PC90_DANRE
AccessioniPrimary (citable) accession number: Q6PC90
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health