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Q6PC19

- SSU72_DANRE

UniProt

Q6PC19 - SSU72_DANRE

Protein

RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Gene

ssu72

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    GO - Molecular functioni

    1. phosphoprotein phosphatase activity Source: UniProtKB-KW

    GO - Biological processi

    1. mRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    mRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC:3.1.3.16)
    Short name:
    CTD phosphatase SSU72
    Gene namesi
    Name:ssu72
    ORF Names:zgc:73143
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Chromosome 22

    Organism-specific databases

    ZFINiZDB-GENE-040426-1689. ssu72.

    Subcellular locationi

    Nucleus By similarity. Cytoplasm By similarity
    Note: Predominantly in the cytosol.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 194194RNA polymerase II subunit A C-terminal domain phosphatase SSU72PRO_0000330016Add
    BLAST

    Proteomic databases

    PRIDEiQ6PC19.

    Expressioni

    Gene expression databases

    BgeeiQ6PC19.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6PC19.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili160 – 18526Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SSU72 phosphatase family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    GeneTreeiENSGT00390000010165.
    HOGENOMiHOG000183445.
    HOVERGENiHBG059831.
    InParanoidiQ6PC19.
    KOiK15544.
    OMAiNRPFLHT.
    OrthoDBiEOG7C2R2M.
    PhylomeDBiQ6PC19.
    TreeFamiTF300194.

    Family and domain databases

    InterProiIPR006811. RNA_pol_II_suA.
    [Graphical view]
    PANTHERiPTHR20383. PTHR20383. 1 hit.
    PfamiPF04722. Ssu72. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6PC19-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPPHPLRVAV VCSSNQNRSM EAHNILSKRG FDVRSFGTGT HVKLPGPAPD    50
    KPNIYDFKTT YEQMYNDLVR KDKELYTQNG ILHMLDRNKR IKSRPERFQS 100
    CRDQFDLVIT CEERVYDQVL EDLNSREQES FQPVHVINVD IQDNHEEATL 150
    GAFLICELCQ CIQHTDDMEN EMDELLQEFE EKSHRPFLHS VCFY 194
    Length:194
    Mass (Da):22,793
    Last modified:July 5, 2004 - v1
    Checksum:i288F8BE70DBD7880
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC059504 mRNA. Translation: AAH59504.1.
    RefSeqiNP_957022.1. NM_200728.1.
    UniGeneiDr.76327.

    Genome annotation databases

    EnsembliENSDART00000041895; ENSDARP00000041894; ENSDARG00000031216.
    GeneIDi393701.
    KEGGidre:393701.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC059504 mRNA. Translation: AAH59504.1 .
    RefSeqi NP_957022.1. NM_200728.1.
    UniGenei Dr.76327.

    3D structure databases

    ProteinModelPortali Q6PC19.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q6PC19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSDART00000041895 ; ENSDARP00000041894 ; ENSDARG00000031216 .
    GeneIDi 393701.
    KEGGi dre:393701.

    Organism-specific databases

    CTDi 29101.
    ZFINi ZDB-GENE-040426-1689. ssu72.

    Phylogenomic databases

    GeneTreei ENSGT00390000010165.
    HOGENOMi HOG000183445.
    HOVERGENi HBG059831.
    InParanoidi Q6PC19.
    KOi K15544.
    OMAi NRPFLHT.
    OrthoDBi EOG7C2R2M.
    PhylomeDBi Q6PC19.
    TreeFami TF300194.

    Miscellaneous databases

    NextBioi 20814704.
    PROi Q6PC19.

    Gene expression databases

    Bgeei Q6PC19.

    Family and domain databases

    InterProi IPR006811. RNA_pol_II_suA.
    [Graphical view ]
    PANTHERi PTHR20383. PTHR20383. 1 hit.
    Pfami PF04722. Ssu72. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Wild-type.
      Tissue: Eye.

    Entry informationi

    Entry nameiSSU72_DANRE
    AccessioniPrimary (citable) accession number: Q6PC19
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3