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Q6PC19

- SSU72_DANRE

UniProt

Q6PC19 - SSU72_DANRE

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Protein
RNA polymerase II subunit A C-terminal domain phosphatase SSU72
Gene
ssu72, zgc:73143
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination By similarity.

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB-KW

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

mRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC:3.1.3.16)
Short name:
CTD phosphatase SSU72
Gene namesi
Name:ssu72
ORF Names:zgc:73143
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 22

Organism-specific databases

ZFINiZDB-GENE-040426-1689. ssu72.

Subcellular locationi

Nucleus By similarity. Cytoplasm By similarity
Note: Predominantly in the cytosol By similarity.

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 194194RNA polymerase II subunit A C-terminal domain phosphatase SSU72
PRO_0000330016Add
BLAST

Proteomic databases

PRIDEiQ6PC19.

Expressioni

Gene expression databases

BgeeiQ6PC19.

Structurei

3D structure databases

ProteinModelPortaliQ6PC19.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili160 – 18526 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the SSU72 phosphatase family.

Keywords - Domaini

Coiled coil

Phylogenomic databases

GeneTreeiENSGT00390000010165.
HOGENOMiHOG000183445.
HOVERGENiHBG059831.
InParanoidiQ6PC19.
KOiK15544.
OMAiNRPFLHT.
OrthoDBiEOG7C2R2M.
PhylomeDBiQ6PC19.
TreeFamiTF300194.

Family and domain databases

InterProiIPR006811. RNA_pol_II_suA.
[Graphical view]
PANTHERiPTHR20383. PTHR20383. 1 hit.
PfamiPF04722. Ssu72. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PC19-1 [UniParc]FASTAAdd to Basket

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MPPHPLRVAV VCSSNQNRSM EAHNILSKRG FDVRSFGTGT HVKLPGPAPD    50
KPNIYDFKTT YEQMYNDLVR KDKELYTQNG ILHMLDRNKR IKSRPERFQS 100
CRDQFDLVIT CEERVYDQVL EDLNSREQES FQPVHVINVD IQDNHEEATL 150
GAFLICELCQ CIQHTDDMEN EMDELLQEFE EKSHRPFLHS VCFY 194
Length:194
Mass (Da):22,793
Last modified:July 5, 2004 - v1
Checksum:i288F8BE70DBD7880
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC059504 mRNA. Translation: AAH59504.1.
RefSeqiNP_957022.1. NM_200728.1.
UniGeneiDr.76327.

Genome annotation databases

EnsembliENSDART00000041895; ENSDARP00000041894; ENSDARG00000031216.
GeneIDi393701.
KEGGidre:393701.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC059504 mRNA. Translation: AAH59504.1 .
RefSeqi NP_957022.1. NM_200728.1.
UniGenei Dr.76327.

3D structure databases

ProteinModelPortali Q6PC19.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6PC19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000041895 ; ENSDARP00000041894 ; ENSDARG00000031216 .
GeneIDi 393701.
KEGGi dre:393701.

Organism-specific databases

CTDi 29101.
ZFINi ZDB-GENE-040426-1689. ssu72.

Phylogenomic databases

GeneTreei ENSGT00390000010165.
HOGENOMi HOG000183445.
HOVERGENi HBG059831.
InParanoidi Q6PC19.
KOi K15544.
OMAi NRPFLHT.
OrthoDBi EOG7C2R2M.
PhylomeDBi Q6PC19.
TreeFami TF300194.

Miscellaneous databases

NextBioi 20814704.
PROi Q6PC19.

Gene expression databases

Bgeei Q6PC19.

Family and domain databases

InterProi IPR006811. RNA_pol_II_suA.
[Graphical view ]
PANTHERi PTHR20383. PTHR20383. 1 hit.
Pfami PF04722. Ssu72. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Wild-type.
    Tissue: Eye.

Entry informationi

Entry nameiSSU72_DANRE
AccessioniPrimary (citable) accession number: Q6PC19
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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