Q6PBF0 (RL8_XENTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
60S ribosomal protein L8

Gene names

Name:	rpl8
ORF Names:	TTpA008p15.1

Organism

Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Taxonomic identifier

8364 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Silurana

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the ribosomal protein L2P family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 257	256	60S ribosomal protein L8		PRO_0000129748

Sequences

	Sequence		Length	Mass (Da)
	Q6PBF0 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: 20184EC3ACB097A7	FASTA	257	27,927
	10 20 30 40 50 60 MGRVIRGQRK GAGSVFKAHV KHRKGAAKLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK 70 80 90 100 110 120 VAFRDPYRFK KRTELFVAAE GIHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCVEEKP 130 140 150 160 170 180 GDRGKLARAS GNYATVISHN PETKKTRVKL PSGSKKVISS ANRAIVGVVA GGGRIDKPIL 190 200 210 220 230 240 KAGRAYHKYK AKRNCWPRVR GVAMNPVEHP FGGGNHQHIG KPSTIRRDAP AGRKVGLIAA 250 RRTGRLRGTK TVQEKEN

References

[1]	Sanger Xenopus tropicalis EST/cDNA project Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Tadpole.
[2]	NIH - Xenopus Gene Collection (XGC) project Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR760793 mRNA. Translation: CAJ83193.1. BC059744 mRNA. Translation: AAH59744.1.
RefSeq	NP_988925.1. NM_203594.1.
UniGene	Str.7118.
3D structure databases
ProteinModelPortal	Q6PBF0.
SMR	Q6PBF0. Positions 2-246.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6PBF0.
Proteomic databases
PRIDE	Q6PBF0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSXETT00000033787; ENSXETP00000033787; ENSXETG00000015483.
GeneID	394521.
KEGG	xtr:394521.
Organism-specific databases
CTD	6132.
Xenbase	XB-GENE-482209. rpl8.
Phylogenomic databases
eggNOG	veNOG04334.
GeneTree	ENSGT00390000009907.
HOVERGEN	HBG079431.
OMA	PFVKAGK.
OrthoDB	EOG4XKV7P.
Gene expression databases
Bgee	Q6PBF0.
Family and domain databases
InterPro	IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR022666. Rbsml_prot_L2_RNA-bd_dom. IPR002171. Ribosomal_L2. IPR014726. Ribosomal_L2_3. IPR023672. Ribosomal_L2_arc. IPR022669. Ribosomal_L2_C. IPR022671. Ribosomal_L2_CS. IPR014722. Transl_SH3-like_sub. IPR008991. Translation_prot_SH3-like. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit. G3DSA:2.30.30.30. Ribosomal_L2. 1 hit. G3DSA:4.10.950.10. Ribosomal_L2. 1 hit.
KO	K02938.
PANTHER	PTHR13691. Ribosomal_L2. 1 hit.
Pfam	PF00181. Ribosomal_L2. 1 hit. PF03947. Ribosomal_L2_C. 1 hit. [Graphical view]
PIRSF	PIRSF002158. Ribosomal_L2. 1 hit.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF50104. Transl_SH3_like. 1 hit.
PROSITE	PS00467. RIBOSOMAL_L2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL8_XENTR

Accession

Primary (citable) accession number: Q6PBF0
Secondary accession number(s): Q28HP9

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 31, 2004
Last sequence update:	January 23, 2007
Last modified:	November 16, 2011
This is version 57 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program