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Protein

40S ribosomal protein S4

Gene

rps4

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-XTR-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-XTR-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-XTR-6791226. Major pathway of rRNA processing in the nucleolus.
R-XTR-72649. Translation initiation complex formation.
R-XTR-72689. Formation of a pool of free 40S subunits.
R-XTR-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-XTR-72702. Ribosomal scanning and start codon recognition.
R-XTR-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-XTR-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-XTR-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4
Gene namesi
Name:rps4
Synonyms:rps4x
ORF Names:TTpA012h08.1
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-967201. rps4x.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 26326240S ribosomal protein S4PRO_0000130827Add
BLAST

Proteomic databases

PaxDbiQ6PBC4.

Interactioni

Protein-protein interaction databases

IntActiQ6PBC4. 2 interactions.
STRINGi8364.ENSXETP00000056755.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini42 – 10463S4 RNA-bindingAdd
BLAST

Sequence similaritiesi

Belongs to the ribosomal protein S4e family.Curated
Contains 1 S4 RNA-binding domain.Curated

Phylogenomic databases

eggNOGiKOG0378. Eukaryota.
COG1471. LUCA.
GeneTreeiENSGT00390000005569.
HOGENOMiHOG000231325.
HOVERGENiHBG000935.
InParanoidiQ6PBC4.
KOiK02987.
OMAiHIQLNLH.
OrthoDBiEOG77WWD1.
TreeFamiTF300612.

Family and domain databases

HAMAPiMF_00485. Ribosomal_S4e.
InterProiIPR032277. 40S_S4_C.
IPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiPF16121. 40S_S4_C. 1 hit.
PF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6PBC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN
60 70 80 90 100
RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIEKTGEHFR
110 120 130 140 150
LVYDTKGRFA VHRITAEEAK YKLCKVRKTW VGTKGIPHLV THDARTIRYP
160 170 180 190 200
DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER
210 220 230 240 250
HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE
260
ERDKRLAAKQ SSG
Length:263
Mass (Da):29,622
Last modified:January 23, 2007 - v3
Checksum:iA1C9B93A9B4D5CC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR760832 mRNA. Translation: CAJ83152.1.
BC059771 mRNA. Translation: AAH59771.1.
BC077671 mRNA. Translation: AAH77671.1.
RefSeqiNP_988912.1. NM_203581.3.
XP_012823602.1. XM_012968148.1.
UniGeneiStr.65146.

Genome annotation databases

EnsembliENSXETT00000056755; ENSXETP00000056755; ENSXETG00000027073.
GeneIDi394507.
KEGGixtr:394507.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR760832 mRNA. Translation: CAJ83152.1.
BC059771 mRNA. Translation: AAH59771.1.
BC077671 mRNA. Translation: AAH77671.1.
RefSeqiNP_988912.1. NM_203581.3.
XP_012823602.1. XM_012968148.1.
UniGeneiStr.65146.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6PBC4. 2 interactions.
STRINGi8364.ENSXETP00000056755.

Proteomic databases

PaxDbiQ6PBC4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000056755; ENSXETP00000056755; ENSXETG00000027073.
GeneIDi394507.
KEGGixtr:394507.

Organism-specific databases

CTDi6191.
XenbaseiXB-GENE-967201. rps4x.

Phylogenomic databases

eggNOGiKOG0378. Eukaryota.
COG1471. LUCA.
GeneTreeiENSGT00390000005569.
HOGENOMiHOG000231325.
HOVERGENiHBG000935.
InParanoidiQ6PBC4.
KOiK02987.
OMAiHIQLNLH.
OrthoDBiEOG77WWD1.
TreeFamiTF300612.

Enzyme and pathway databases

ReactomeiR-XTR-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-XTR-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-XTR-6791226. Major pathway of rRNA processing in the nucleolus.
R-XTR-72649. Translation initiation complex formation.
R-XTR-72689. Formation of a pool of free 40S subunits.
R-XTR-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-XTR-72702. Ribosomal scanning and start codon recognition.
R-XTR-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-XTR-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-XTR-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Family and domain databases

HAMAPiMF_00485. Ribosomal_S4e.
InterProiIPR032277. 40S_S4_C.
IPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiPF16121. 40S_S4_C. 1 hit.
PF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Sanger Xenopus tropicalis EST/cDNA project
    Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Tadpole.
  2. NIH - Xenopus Gene Collection (XGC) project
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo and Tadpole.

Entry informationi

Entry nameiRS4_XENTR
AccessioniPrimary (citable) accession number: Q6PBC4
Secondary accession number(s): Q28HL4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: January 23, 2007
Last modified: June 8, 2016
This is version 83 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.