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Protein

40S ribosomal protein S4

Gene

rps4

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-XTR-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-XTR-1799339 SRP-dependent cotranslational protein targeting to membrane
R-XTR-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-XTR-72649 Translation initiation complex formation
R-XTR-72689 Formation of a pool of free 40S subunits
R-XTR-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-XTR-72702 Ribosomal scanning and start codon recognition
R-XTR-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-XTR-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-XTR-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4
Gene namesi
Name:rps4
Synonyms:rps4x
ORF Names:TTpA012h08.1
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-967201 rps4x

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001308272 – 26340S ribosomal protein S4Add BLAST262

Proteomic databases

PaxDbiQ6PBC4

Expressioni

Gene expression databases

BgeeiENSXETG00000027073

Interactioni

Protein-protein interaction databases

IntActiQ6PBC4, 2 interactors
MINTiQ6PBC4
STRINGi8364.ENSXETP00000056755

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 104S4 RNA-bindingAdd BLAST63

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0378 Eukaryota
COG1471 LUCA
GeneTreeiENSGT00390000005569
HOGENOMiHOG000231325
HOVERGENiHBG000935
InParanoidiQ6PBC4
KOiK02987
OMAiRKDYKFP
OrthoDBiEOG091G0MYF
TreeFamiTF300612

Family and domain databases

CDDicd00165 S4, 1 hit
Gene3Di2.30.30.30, 1 hit
2.40.50.740, 1 hit
HAMAPiMF_00485 Ribosomal_S4e, 1 hit
InterProiView protein in InterPro
IPR032277 40S_S4_C
IPR005824 KOW
IPR014722 Rib_L2_dom2
IPR000876 Ribosomal_S4e
IPR013845 Ribosomal_S4e_central_region
IPR038237 Ribosomal_S4e_central_sf
IPR013843 Ribosomal_S4e_N
IPR018199 Ribosomal_S4e_N_CS
IPR002942 S4_RNA-bd
PANTHERiPTHR11581 PTHR11581, 1 hit
PfamiView protein in Pfam
PF16121 40S_S4_C, 1 hit
PF00467 KOW, 1 hit
PF00900 Ribosomal_S4e, 1 hit
PF08071 RS4NT, 1 hit
PF01479 S4, 1 hit
PIRSFiPIRSF002116 Ribosomal_S4, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667 Ribosomal_S4e_central, 1 hit
SMARTiView protein in SMART
SM00363 S4, 1 hit
PROSITEiView protein in PROSITE
PS00528 RIBOSOMAL_S4E, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6PBC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN
60 70 80 90 100
RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIEKTGEHFR
110 120 130 140 150
LVYDTKGRFA VHRITAEEAK YKLCKVRKTW VGTKGIPHLV THDARTIRYP
160 170 180 190 200
DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER
210 220 230 240 250
HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE
260
ERDKRLAAKQ SSG
Length:263
Mass (Da):29,622
Last modified:January 23, 2007 - v3
Checksum:iA1C9B93A9B4D5CC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR760832 mRNA Translation: CAJ83152.1
BC059771 mRNA Translation: AAH59771.1
BC077671 mRNA Translation: AAH77671.1
RefSeqiNP_988912.1, NM_203581.3
XP_012823602.1, XM_012968148.1
UniGeneiStr.65146

Genome annotation databases

EnsembliENSXETT00000056755; ENSXETP00000056755; ENSXETG00000027073
GeneIDi394507
KEGGixtr:394507

Similar proteinsi

Entry informationi

Entry nameiRS4_XENTR
AccessioniPrimary (citable) accession number: Q6PBC4
Secondary accession number(s): Q28HL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 94 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health