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Protein
Submitted name:

Grm3 protein

Gene

Grm3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • calcium channel regulator activity Source: MGI
  • group II metabotropic glutamate receptor activity Source: MGI

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Grm3 proteinImported
Gene namesi
Name:Grm3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1351340. Grm3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei149 – 17325HelicalSequence analysisAdd
BLAST
Transmembranei188 – 20821HelicalSequence analysisAdd
BLAST
Transmembranei220 – 24122HelicalSequence analysisAdd
BLAST
Transmembranei262 – 28322HelicalSequence analysisAdd
BLAST
Transmembranei311 – 33020HelicalSequence analysisAdd
BLAST
Transmembranei342 – 36423HelicalSequence analysisAdd
BLAST
Transmembranei370 – 39425HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: GO_Central
  • neuron projection Source: MGI
  • postsynaptic density Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ6PAT5.

Expressioni

Gene expression databases

BgeeiQ6PAT5.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000004076.

Structurei

3D structure databases

ProteinModelPortaliQ6PAT5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini150 – 416267G_PROTEIN_RECEP_F3_4InterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410XR6W. LUCA.
KOG1056. Eukaryota.
HOVERGENiHBG107965.

Family and domain databases

InterProiIPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR001234. GPCR_3_mtglu_rcpt_3.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01053. MTABOTROPC3R.
PR00593. MTABOTROPICR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6PAT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GKKLYKDYLL KINFTAPFNP NKGADSIVKF DTYGDGMGRY NVFNFQHIGG
60 70 80 90 100
KYSYLKVGHW AETLYLDVDS IHWSRNSVPT SQCSDPCAPN EMKNMQPGDV
110 120 130 140 150
CCWICIPCEP YEYLVDEFTC MDCGPGQWPT ADLSGCYNLP EDYIRWEDAW
160 170 180 190 200
AIGPVTIACL GFMCTCIVIT VFIKHNNTPL VKASGRELCY ILLFGVSLSY
210 220 230 240 250
CMTFFFIAKP SPVICALRRL GLGTSFAICY SALLTKTNCI ARIFDGVKNG
260 270 280 290 300
AQRPKFISPS SQVFICLGLI LVQIVMVSVW LILETPGTRR YTLPEKRETV
310 320 330 340 350
ILKCNVKDSS MLISLTYDVV LVILCTVYAF KTRKCPENFN EAKFIGFTMY
360 370 380 390 400
TTCIIWLAFL PIFYVTSSDY RVQTTTMCIS VSLSGFVVLG CLFAPKVHIV
410 420 430 440 450
LFQPQKNVVT HRLHLNRFSV SGTATTYSQS SASTYVPTVC NGREVLDSTT

SSL
Length:453
Mass (Da):50,757
Last modified:July 5, 2004 - v1
Checksum:iD4C03B8F596805D4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060060 mRNA. Translation: AAH60060.1.
UniGeneiMm.318966.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060060 mRNA. Translation: AAH60060.1.
UniGeneiMm.318966.

3D structure databases

ProteinModelPortaliQ6PAT5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000004076.

Proteomic databases

PaxDbiQ6PAT5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1351340. Grm3.

Phylogenomic databases

eggNOGiENOG410XR6W. LUCA.
KOG1056. Eukaryota.
HOVERGENiHBG107965.

Miscellaneous databases

ChiTaRSiGrm3. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiQ6PAT5.

Family and domain databases

InterProiIPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR001234. GPCR_3_mtglu_rcpt_3.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01053. MTABOTROPC3R.
PR00593. MTABOTROPICR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6Imported.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ6PAT5_MOUSE
AccessioniPrimary (citable) accession number: Q6PAT5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: December 9, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.