Rbl1

Functionⁱ

GO - Biological processⁱ

cell cycle Source: InterPro
regulation of cell cycle Source: InterPro
regulation of transcription from RNA polymerase II promoter Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Retinoblastoma-like 1 (P107)Imported
Gene namesⁱ	Name:Rbl1Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:103300. Rbl1.

Subcellular locationⁱ

GO (Gene Ontology) annotation

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q6PAR4.

PaxDbⁱ

Q6PAR4.

Expressionⁱ

Gene expression databases

Genevisibleⁱ	Q6PAR4. MM.

Genevisibleⁱ

Q6PAR4. MM.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6PAR4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	70 – 212	DUF3452InterPro annotationAdd BLAST	143
Domainⁱ	385 – 578	RB_AInterPro annotationAdd BLAST	194
Domainⁱ	800 – 934	CYCLINInterPro annotationAdd BLAST	135
Domainⁱ	947 – 1063	Rb_CInterPro annotationAdd BLAST	117

Phylogenomic databases

eggNOGⁱ	KOG1010. Eukaryota. ENOG410XQF7. LUCA.
HOVERGENⁱ	HBG017710.
KEGG Orthology (KO) More...KOⁱ	K04681.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00043. CYCLIN. 1 hit.
Gene3Dⁱ	1.10.472.10. 3 hits.
InterProⁱ	View protein in InterPro IPR013763. Cyclin-like. IPR002720. RB_A. IPR002719. RB_B. IPR015030. RB_C. IPR028309. RB_fam. IPR024599. RB_N. IPR028310. RBL1.
PANTHERⁱ	PTHR13742. PTHR13742. 1 hit. PTHR13742:SF24. PTHR13742:SF24. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF11934. DUF3452. 1 hit. PF01858. RB_A. 1 hit. PF01857. RB_B. 1 hit. PF08934. Rb_C. 1 hit.
SMARTⁱ	View protein in SMART SM00385. CYCLIN. 1 hit. SM01367. DUF3452. 1 hit. SM01368. RB_A. 1 hit. SM01369. Rb_C. 1 hit.
SUPFAMⁱ	SSF47954. SSF47954. 3 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q6PAR4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MFEDEPHAEG AAAVAAAREA LQALCQELNL DEGSAAEALD DFTAIRGNYS 
        60         70         80         90        100
LEGEVIHWLA CSLYVACRKS IIPTVGKGVM EGNCVSLTRI LRSAKLSLIQ 
       110        120        130        140        150
FFSKMKKWMD MSNLPQEFRE RIERLERNFE VSTVIFKKFE PIFLDIFQNP 
       160        170        180        190        200
YEEPPKLPRS RKQRRIPCSV RDLFNFCWTL FVYTKGNFRM IGDDLVNSYH 
       210        220        230        240        250
LLLCCLDLIF ANAIMCPNRR DLLNPSFKGL PSDFHAPDFK AAEEPPCIIA 
       260        270        280        290        300
VLCDLHDGLL VEAKGIKEHY FKPYISKLFD KKILKGECLL DLSSFTDNSK 
       310        320        330        340        350
AVNKEYEEYV LTVGDFDERI FLGADAEEEI GTPRKFTADT PFGKLTSQAS 
       360        370        380        390        400
VECNLQQHFE KKRSFAPSTP LTGRRYLQEK EAVTTPVASA TQSVSRLQSI 
       410        420        430        440        450
VAGLKSAPSE QLLNIFESCM RNPMGNIIKI VKGIGETFCQ HYTQSTDKQP 
       460        470        480        490        500
GSHIDFAVNR LKLAEILYYK ILETIMVQET RRLHGMDMSV LLEQDIFHKS 
       510        520        530        540        550
LMACCLEIVL FAYSSPRTFP WIIEVLDLQP FYFYKVIEVV IRSEEGLSRD 
       560        570        580        590        600
MVKHLNSIEE QILESLAWTN NSALWEALHA SANRVPPCEE VIFPNNFEIG 
       610        620        630        640        650
NGGNVQGHLP MMPMSPIIHP RVKEVRTDSG SLRQDMQPLS PISVHERYSS 
       660        670        680        690        700
PAAGSAKRRL FGDDPPKDTL MDKIMAEGTK LKIAPSSVTA ESLSISPGQA 
       710        720        730        740        750
LLTMATTTVT GTTGRKVTVP LHGIANDAGE ITLVPISMNP TQESTAESPV 
       760        770        780        790        800
SLTAQSLIGT SPKQTHLTKA QDAHLTGVSK PKRTGSLALF YRKVYHLASV 
       810        820        830        840        850
RLRDLCLKLD VSNELRRKIW TCFEFTLVHC PDLMKDRHLD QLLLCAFYIM 
       860        870        880        890        900
AKVTKEERTF QEIMKSYRNQ PQANSHVYRS VLLKSIPGGV VVYNGDCEMT 
       910        920        930        940        950
DGDIEDATKT PNCSSEPVKE ERGDLIKFYN TVYVGRVKSF ALKYDLSNQD 
       960        970        980        990       1000
HIMDAPPLSP FPHIKQQPGS PRRISQQHSL YVSPHKNGAG LTPRSALLYK 
      1010       1020       1030       1040       1050
FNGSPSKSLK DINNMIRQGE QKTKKRVIAI SGDADSPAKR LCQENDDVLL 
      1060 
KRLQDVVSER ANH

Length:1,063

Mass (Da):119,494

Last modified:July 5, 2004 - v1

Checksum:ⁱ723DE73069DBB339

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC060124 mRNA. Translation: AAH60124.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_035379.2. NM_011249.2.
UniGeneⁱ	Mm.244671.

Genome annotation databases

GeneIDⁱ	19650.
KEGGⁱ	mmu:19650.

Similar proteinsⁱ

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q6PAR4	P28749 UPI0005D0419A UPI0005D02726 UPI000951AA34 UPI00042C887C UPI0009531817 UPI0002BD0A34 UPI0007044638 UPI00083F1DA7 UPI00044059B0 +131	Homo sapiens (Human) Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus) Physeter catodon (Sperm whale) (Physeter macrocephalus) Orcinus orca (Killer whale) Tupaia chinensis (Chinese tree shrew) Papio anubis (Olive baboon) Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) Macaca nemestrina (Pig-tailed macaque) And more	1,068	UniRef90_P28749	Cluster: Retinoblastoma-like protein 1	142

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q6PAR4	P28749 UPI0005D0419A UPI0005D02726 UPI000951AA34 UPI00042C887C UPI0009531817 UPI0002BD0A34 UPI0007044638 UPI00083F1DA7 UPI00044059B0 +338	Homo sapiens (Human) Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus) Physeter catodon (Sperm whale) (Physeter macrocephalus) Orcinus orca (Killer whale) Tupaia chinensis (Chinese tree shrew) Papio anubis (Olive baboon) Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) Macaca nemestrina (Pig-tailed macaque) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) And more	1,068	UniRef50_P28749	Cluster: Retinoblastoma-like protein 1	349

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC060124 mRNA. Translation: AAH60124.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_035379.2. NM_011249.2.
UniGeneⁱ	Mm.244671.

3D structure databases

ProteinModelPortalⁱ	Q6PAR4.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	Q6PAR4.

PaxDbⁱ

Q6PAR4.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	19650.
KEGGⁱ	mmu:19650.

Organism-specific databases

CTDⁱ	5933.
MGIⁱ	MGI:103300. Rbl1.

Phylogenomic databases

eggNOGⁱ	KOG1010. Eukaryota. ENOG410XQF7. LUCA.
HOVERGENⁱ	HBG017710.
KEGG Orthology (KO) More...KOⁱ	K04681.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Genevisibleⁱ	Q6PAR4. MM.

Genevisibleⁱ

Q6PAR4. MM.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00043. CYCLIN. 1 hit.
Gene3Dⁱ	1.10.472.10. 3 hits.
InterProⁱ	View protein in InterPro IPR013763. Cyclin-like. IPR002720. RB_A. IPR002719. RB_B. IPR015030. RB_C. IPR028309. RB_fam. IPR024599. RB_N. IPR028310. RBL1.
PANTHERⁱ	PTHR13742. PTHR13742. 1 hit. PTHR13742:SF24. PTHR13742:SF24. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF11934. DUF3452. 1 hit. PF01858. RB_A. 1 hit. PF01857. RB_B. 1 hit. PF08934. Rb_C. 1 hit.
SMARTⁱ	View protein in SMART SM00385. CYCLIN. 1 hit. SM01367. DUF3452. 1 hit. SM01368. RB_A. 1 hit. SM01369. Rb_C. 1 hit.
SUPFAMⁱ	SSF47954. SSF47954. 3 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q6PAR4_MOUSE
Accessionⁱ	Q6PAR4Primary (citable) accession number: Q6PAR4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	September 27, 2017
	This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q6PAR4 (Q6PAR4_MOUSE)

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Retinoblastoma-like 1 (P107)

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Nucleus

Other locations

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6PAR4 (Q6PAR4_MOUSE)

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Retinoblastoma-like 1 (P107)

Rbl1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ