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Protein

AT-hook DNA-binding motif-containing protein 1

Gene

Ahdc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi395 – 40713A.T hook 1Add
BLAST
DNA bindingi541 – 55313A.T hook 2Add
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
AT-hook DNA-binding motif-containing protein 1
Gene namesi
Name:Ahdc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2444218. Ahdc1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 15941594AT-hook DNA-binding motif-containing protein 1PRO_0000313825Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei79 – 791N6-acetyllysineCombined sources
Modified residuei267 – 2671PhosphoserineBy similarity
Modified residuei593 – 5931PhosphoserineBy similarity
Modified residuei825 – 8251PhosphoserineCombined sources
Modified residuei842 – 8421PhosphoserineCombined sources
Modified residuei892 – 8921PhosphoserineCombined sources
Modified residuei1060 – 10601PhosphoserineBy similarity
Modified residuei1180 – 11801PhosphoserineCombined sources
Modified residuei1315 – 13151PhosphoserineCombined sources
Modified residuei1317 – 13171PhosphoserineCombined sources
Modified residuei1392 – 13921PhosphoserineCombined sources
Modified residuei1394 – 13941PhosphothreonineCombined sources
Modified residuei1396 – 13961PhosphoserineCombined sources
Modified residuei1498 – 14981PhosphoserineBy similarity
Modified residuei1540 – 15401PhosphoserineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ6PAL7.
MaxQBiQ6PAL7.
PaxDbiQ6PAL7.
PeptideAtlasiQ6PAL7.
PRIDEiQ6PAL7.

PTM databases

iPTMnetiQ6PAL7.
PhosphoSiteiQ6PAL7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000037692.
CleanExiMM_AHDC1.
GenevisibleiQ6PAL7. MM.

Interactioni

Protein-protein interaction databases

BioGridi231029. 1 interaction.
IntActiQ6PAL7. 1 interaction.
MINTiMINT-4119626.
STRINGi10090.ENSMUSP00000047113.

Structurei

3D structure databases

ProteinModelPortaliQ6PAL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi25 – 459435Pro-richAdd
BLAST
Compositional biasi661 – 820160Gly-richAdd
BLAST

Sequence similaritiesi

Contains 2 A.T hook DNA-binding domains.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IHGR. Eukaryota.
ENOG4110FBK. LUCA.
GeneTreeiENSGT00390000018883.
HOGENOMiHOG000033863.
HOVERGENiHBG094919.
InParanoidiQ6PAL7.
OMAiSQCAGRC.
OrthoDBiEOG091G00VR.
PhylomeDBiQ6PAL7.
TreeFamiTF332128.

Family and domain databases

InterProiIPR032757. DUF4683.
[Graphical view]
PfamiPF15735. DUF4683. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6PAL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVKPQGLVV TSSAVCSSPD YLREPKYYPG GPPTPRPLLP TRPPASPPDK
60 70 80 90 100
AFSTHTFSEN PRPPPRRDPS SRRPPVLAKG DDLLPPRAAR PVSQAHCPSP
110 120 130 140 150
APDNSSLRHW DNGRVNLRPV VQLIDIMKDL TRLSQDLQHS GVHLDCGGLR
160 170 180 190 200
LSRPPAPPPG DLQYSFFSSP SLANSIRSPE ERANPHTKSE RPSHPLYEPE
210 220 230 240 250
PEPRDSPQPG QGHGPGAAAT ATGLPPEPEP DGPDYSELAD ADILSELASL
260 270 280 290 300
TCPEAQLLEA QALEPPSPQP EPQLLDPQPR FLDPQALEPL GEGLELPPLQ
310 320 330 340 350
PLADPLGLPS LTLQALDTLP DSLESQLLDP QALDPLPKLL DVPGRRLEPQ
360 370 380 390 400
QSLGHCQLAE PLRLDLCSPH GPPGPEGHPK YALRRTDRPK ILCRRRKAGR
410 420 430 440 450
GRKADSGPEG RLLPLPMPTG LAAALAEPPP LPPPPPPTLS GPGPVPELEP
460 470 480 490 500
ESSQTPMVPT RKGKCRGVRR MVVKMAKIPV SLGRRNKTTY KVSSLSSSLS
510 520 530 540 550
VEGKELGLRV SSEPTPLLKM KNNGRNVVVV FPPGEMPIIL KRKRGRPPKN
560 570 580 590 600
LLLGPGKPKE PTVVAAEAAT VTAATMAMPE VKKRRRRKQK LASPQPSYAA
610 620 630 640 650
DANDSKAEYS DVLAKLAFLN RQSQCAGRCS PPRCWTPSEP ESVHQAPDTQ
660 670 680 690 700
SISQFLHRVQ GFRRRGGKTG GFGGRGGGHA AKAARCSFSD FFEGIGKKKK
710 720 730 740 750
VVAVAAPGLV GPGLTELGHP RKRGRGEVDA VTGKPKRKRR SRKNGTLFPE
760 770 780 790 800
QVPSGPGFGE AGAEWVGDKG GGWAPHHGHP GGQAGRNCGF QGTEARAFAS
810 820 830 840 850
TGLESGASGR GSYYAGAPSG QTELSQERQN LFTGYFRSLL DSDDSSDLLD
860 870 880 890 900
FALSASRPES RKASGTYAGP PSSALPAQRG LATFPSRGAK ASPVAVGSSG
910 920 930 940 950
AGADPSFQPV LPSRQTFPPG RATSYGITPA TSDCRAAETF PKLAPPPSAV
960 970 980 990 1000
ARSPTTHPPA NTYPPQYGGY GAGQSVFASA KPFSGQDCAN SKDCSFAYGS
1010 1020 1030 1040 1050
GNSLPASPSS AHSAGYAPPP TGGPCLPPSK ASFFNSSEGG PFSGSAPTPL
1060 1070 1080 1090 1100
RCDSRASTVS PGGYMVPKGT TASAASVASS SSSSFQPSPE NCRQFVGASQ
1110 1120 1130 1140 1150
WPFRQGYGGL DWASEAFSQL YNPNFDCHGS EPNVILDISN YTPQKVKQQT
1160 1170 1180 1190 1200
AVSETFSESS SDSTQFSQPV GGGGFRRANS EASSSEGQSS LSSLEKLMMD
1210 1220 1230 1240 1250
WNEASSAPGY NWNQSVLFQS SSKPGRGRRK KVDLFEASHL GFSTSTSATA
1260 1270 1280 1290 1300
SGYPSKRSTG PRQPRGGRGS GACSAKKERG GTAAKAKFIP KPQPVNPLFQ
1310 1320 1330 1340 1350
DSPDLGLDYY SGDSSMSPLP SQSRAFGVGE RDPCDFMGPY SMNPSTPSDG
1360 1370 1380 1390 1400
TFGQGFHCDS PSLGAAELDG KHFPPLAHPP TVFDAGLQKA YSPTCSPTLG
1410 1420 1430 1440 1450
FKEELRPPPS KLTACEPLKH GLQGASLSHA AQAHLSCRDL PLGQPHYDSP
1460 1470 1480 1490 1500
SCKGTAYWYP PGSAARSPPY EGKVGSGLLA DFLGRTEAVC LSAPHLASPP
1510 1520 1530 1540 1550
ATPKADKEPL EMARPPGPPR GPAAATAGYG CPLLSDLTLS PVPRDSLLPL
1560 1570 1580 1590
QDTAYRYPGF MPQAHPGLGG GPKSGFLGPM AEPHPEDTFT VTSL
Length:1,594
Mass (Da):168,081
Last modified:July 5, 2004 - v1
Checksum:i2DC06E3D70D75DC4
GO

Sequence cautioni

The sequence AAH19130 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti431 – 4311L → LP in AAH42621 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL627184 Genomic DNA. Translation: CAM14379.1.
BC019130 mRNA. Translation: AAH19130.1. Different initiation.
BC042621 mRNA. Translation: AAH42621.1.
BC060231 mRNA. Translation: AAH60231.1.
AK080410 mRNA. Translation: BAC37907.1.
CCDSiCCDS38900.1.
RefSeqiNP_666267.3. NM_146155.3.
XP_006538797.1. XM_006538734.1.
XP_006538799.1. XM_006538736.2.
XP_006538800.1. XM_006538737.1.
XP_006538801.1. XM_006538738.2.
XP_006538802.1. XM_006538739.1.
XP_006538803.1. XM_006538740.1.
XP_006538804.1. XM_006538741.2.
XP_006538805.1. XM_006538742.1.
XP_011248533.1. XM_011250231.1.
UniGeneiMm.31816.
Mm.421391.

Genome annotation databases

EnsembliENSMUST00000044521; ENSMUSP00000047113; ENSMUSG00000037692.
ENSMUST00000105914; ENSMUSP00000101534; ENSMUSG00000037692.
ENSMUST00000105915; ENSMUSP00000101535; ENSMUSG00000037692.
ENSMUST00000105916; ENSMUSP00000101536; ENSMUSG00000037692.
GeneIDi230793.
KEGGimmu:230793.
UCSCiuc008vcc.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL627184 Genomic DNA. Translation: CAM14379.1.
BC019130 mRNA. Translation: AAH19130.1. Different initiation.
BC042621 mRNA. Translation: AAH42621.1.
BC060231 mRNA. Translation: AAH60231.1.
AK080410 mRNA. Translation: BAC37907.1.
CCDSiCCDS38900.1.
RefSeqiNP_666267.3. NM_146155.3.
XP_006538797.1. XM_006538734.1.
XP_006538799.1. XM_006538736.2.
XP_006538800.1. XM_006538737.1.
XP_006538801.1. XM_006538738.2.
XP_006538802.1. XM_006538739.1.
XP_006538803.1. XM_006538740.1.
XP_006538804.1. XM_006538741.2.
XP_006538805.1. XM_006538742.1.
XP_011248533.1. XM_011250231.1.
UniGeneiMm.31816.
Mm.421391.

3D structure databases

ProteinModelPortaliQ6PAL7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi231029. 1 interaction.
IntActiQ6PAL7. 1 interaction.
MINTiMINT-4119626.
STRINGi10090.ENSMUSP00000047113.

PTM databases

iPTMnetiQ6PAL7.
PhosphoSiteiQ6PAL7.

Proteomic databases

EPDiQ6PAL7.
MaxQBiQ6PAL7.
PaxDbiQ6PAL7.
PeptideAtlasiQ6PAL7.
PRIDEiQ6PAL7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044521; ENSMUSP00000047113; ENSMUSG00000037692.
ENSMUST00000105914; ENSMUSP00000101534; ENSMUSG00000037692.
ENSMUST00000105915; ENSMUSP00000101535; ENSMUSG00000037692.
ENSMUST00000105916; ENSMUSP00000101536; ENSMUSG00000037692.
GeneIDi230793.
KEGGimmu:230793.
UCSCiuc008vcc.1. mouse.

Organism-specific databases

CTDi27245.
MGIiMGI:2444218. Ahdc1.

Phylogenomic databases

eggNOGiENOG410IHGR. Eukaryota.
ENOG4110FBK. LUCA.
GeneTreeiENSGT00390000018883.
HOGENOMiHOG000033863.
HOVERGENiHBG094919.
InParanoidiQ6PAL7.
OMAiSQCAGRC.
OrthoDBiEOG091G00VR.
PhylomeDBiQ6PAL7.
TreeFamiTF332128.

Miscellaneous databases

ChiTaRSiAhdc1. mouse.
PROiQ6PAL7.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000037692.
CleanExiMM_AHDC1.
GenevisibleiQ6PAL7. MM.

Family and domain databases

InterProiIPR032757. DUF4683.
[Graphical view]
PfamiPF15735. DUF4683. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAHDC1_MOUSE
AccessioniPrimary (citable) accession number: Q6PAL7
Secondary accession number(s): Q5U5N7, Q8C4Y6, Q8VCU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.