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Protein

Glucose-6-phosphatase

Gene

MGC68455

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei175NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Biological processi

GluconeogenesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphataseUniRule annotation (EC:3.1.3.9UniRule annotation)
Gene namesi
Name:MGC68455Imported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Subcellular locationi

  • Endoplasmic reticulum membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
Transmembranei61 – 80HelicalSequence analysisAdd BLAST20
Transmembranei120 – 140HelicalSequence analysisAdd BLAST21
Transmembranei152 – 174HelicalSequence analysisAdd BLAST23
Transmembranei180 – 201HelicalSequence analysisAdd BLAST22
Transmembranei213 – 237HelicalSequence analysisAdd BLAST25
Transmembranei257 – 279HelicalSequence analysisAdd BLAST23
Transmembranei291 – 308HelicalSequence analysisAdd BLAST18
Transmembranei320 – 344HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Structurei

3D structure databases

ProteinModelPortaliQ6PAE1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 195acidPPcInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the glucose-6-phosphatase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG003560.
KOiK01084.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR016275. Glucose-6-phosphatase.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000905. Glucose-6-phosphatase. 1 hit.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6PAE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMGMDNLHS TGVYVVKYLQ ENFIKSQDWF VFVSFAADLK NTFLILFPIW
60 70 80 90 100
FHISESVGVK LVWVAVIGDW LNLVFKWILF GQRPYWWVHE TTFFVNNSAP
110 120 130 140 150
TILQFPVTCE TGPGSPSGHA MGSSAVYYVM AHAVLSVLLE NKTTLRSQFQ
160 170 180 190 200
RWALWLFFWS VQVNVCLSRV FVAAHFPHQV IAGVCSGMLV AKIFNHVHCI
210 220 230 240 250
YNVSFKRYIY ATLFLFFFAL GFYLILKVFG IDLLWALEKA KRWCARPEWI
260 270 280 290 300
HIDTTPFAGL LRNLGVFFGL GLALDTQMYR DSCREKKGGQ FTFRLCCIMI
310 320 330 340 350
SLLVLHLFDS LELPADKEIL FYFLSFCRSV AVSLTVVAVI PFCISHALQW

QKKKVT
Length:356
Mass (Da):40,990
Last modified:July 5, 2004 - v1
Checksum:i6FB0A67D8408F0E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060354 mRNA. Translation: AAH60354.1.
RefSeqiNP_001083304.1. NM_001089835.1.
UniGeneiXl.5165.

Genome annotation databases

GeneIDi398855.
KEGGixla:398855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC060354 mRNA. Translation: AAH60354.1.
RefSeqiNP_001083304.1. NM_001089835.1.
UniGeneiXl.5165.

3D structure databases

ProteinModelPortaliQ6PAE1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi398855.
KEGGixla:398855.

Phylogenomic databases

HOVERGENiHBG003560.
KOiK01084.

Enzyme and pathway databases

UniPathwayiUPA00138.

Family and domain databases

Gene3Di1.20.144.10. 1 hit.
InterProiIPR016275. Glucose-6-phosphatase.
IPR000326. P_Acid_Pase_2/haloperoxidase.
[Graphical view]
PfamiPF01569. PAP2. 1 hit.
[Graphical view]
PIRSFiPIRSF000905. Glucose-6-phosphatase. 1 hit.
SMARTiSM00014. acidPPc. 1 hit.
[Graphical view]
SUPFAMiSSF48317. SSF48317. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6PAE1_XENLA
AccessioniPrimary (citable) accession number: Q6PAE1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.