Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Lysosomal multispanning membrane protein 5

Gene

Laptm5

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Lysosomal multispanning membrane protein 5Imported
Submitted name:
Lysosomal protein transmembrane 5Imported
Submitted name:
Lysosomal-associated protein transmembrane 5Imported
Gene namesi
Name:Laptm5Imported
ORF Names:rCG_30789Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi621838. Laptm5.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 41HelicalSequence analysisAdd BLAST22
Transmembranei62 – 85HelicalSequence analysisAdd BLAST24
Transmembranei91 – 115HelicalSequence analysisAdd BLAST25
Transmembranei183 – 205HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

  • integral component of plasma membrane Source: InterPro
  • lysosomal membrane Source: InterPro
  • lysosome Source: RGD

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000011054.
ExpressionAtlasiQ6P9Z7. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015198.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IFZA. Eukaryota.
ENOG410YPPU. LUCA.
GeneTreeiENSGT00390000012862.
HOGENOMiHOG000113282.
HOVERGENiHBG052307.
KOiK12387.
OMAiCVWRCYK.
OrthoDBiEOG091G0JRF.
TreeFamiTF330843.

Family and domain databases

InterProiView protein in InterPro
IPR004687. LAPTM4/5.
IPR018396. LAPTM_4A/5.
IPR018397. Lysosomal-assoc_TM_prot5.
PANTHERiPTHR12479:SF13. PTHR12479:SF13. 1 hit.
PfamiView protein in Pfam
PF03821. Mtp. 1 hit.
TIGRFAMsiTIGR00799. mtp. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6P9Z7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRAVPVRQ TCCCFNVRVA TVALAIYHIV MSVLLFIEHV VEVARGKVSC
60 70 80 90 100
RFSKMPYLRL ADLLSSFLLI GVLFIISLSL LFGVVKNREK YLIPFLSLQI
110 120 130 140 150
MDFLLCLLTL LGSYIELPAY LKFARPRPGP SKVPLMTLQL LDFCLSILTL
160 170 180 190 200
CSSYMEVPTY LNFKSMNHMN YLPSQEGMPR SQFINMMLIF SVAFITVLIL
210 220 230 240 250
KVYMFKCVWT CYRFMKHMNS AVEDSSSKLF LKVALPSYEE ALSLPTKTPE
260
GDLAPPPYSE V
Length:261
Mass (Da):29,648
Last modified:July 5, 2004 - v1
Checksum:i5743EABCBE214DDE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07050048 Genomic DNA. No translation available.
BC060517 mRNA. Translation: AAH60517.1.
CH473968 Genomic DNA. Translation: EDL80601.1.
RefSeqiNP_445990.2. NM_053538.2.
UniGeneiRn.24799.

Genome annotation databases

EnsembliENSRNOT00000015198; ENSRNOP00000015198; ENSRNOG00000011054.
GeneIDi89783.
KEGGirno:89783.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ6P9Z7_RAT
AccessioniPrimary (citable) accession number: Q6P9Z7
Secondary accession number(s): F1LN25
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 5, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported