Q6P980 (Q6P980_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase RuleBase RU000414
EC=1.15.1.1 RuleBase RU000414

Gene names

Name:

sod2 Ensembl ENSDARP00000062555 ZFIN ZDB-GENE-030131-7742 EMBL AAH60895.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome] EMBL AAH60895.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000414
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000414
Sequence similarities	Belongs to the iron/manganese superoxide dismutase family. RuleBase RU004477

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU000414
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to cadmium ion Inferred from expression pattern PubMed 16799861. Source: ZFIN response to methylmercury Inferred from direct assay PubMed 15984772. Source: ZFIN superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: InterPro superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6P980 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 7E184E4361F82066	FASTA	224	25,008
	10 20 30 40 50 60 MLCRVGYVRR CAATFNPLLG AVTSRQKHAL PDLTYDYGAL EPHICAEIMQ LHHSKHHATY 70 80 90 100 110 120 VNNLNVTEEK YQEALAKGDV TTQVSLQPAL KFNGGGHINH TIFWTNLSPN GGGEPQGELL 130 140 150 160 170 180 EAIKRDFGSF QKMKEKISAA TVAVQGSGWG WLGFEKESGR LRIAACANQD PLQGTTGLIP 190 200 210 220 LLGIDVWEHA YYLQYKNVRP DYVKAIWNVV NWENVSERFQ AAKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Wild-type EMBL AAH60895.1. Tissue: Eye EMBL AAH60895.1.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000062555.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000062555.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL929182 Genomic DNA. No translation available. BC060895 mRNA. Translation: AAH60895.1.
IPI	IPI00486525.
RefSeq	NP_956270.1. NM_199976.1.
UniGene	Dr.6314.
3D structure databases
SMR	Q6P980. Positions 27-224.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000062556; ENSDARP00000062555; ENSDARG00000042644.
GeneID	335799.
KEGG	dre:335799.
Organism-specific databases
CTD	6648.
ZFIN	ZDB-GENE-030131-7742. sod2.
Phylogenomic databases
GeneTree	ENSGT00390000011877.
HOVERGEN	HBG004451.
InParanoid	Q6P980.
KO	K04564.
OMA	MAPPGKG.
Family and domain databases
InterPro	IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHER	PTHR11404. PTHR11404. 1 hit.
Pfam	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PIRSF	PIRSF000349. SODismutase. 1 hit.
PRINTS	PR01703. MNSODISMTASE.
SUPFAM	SSF46609. SODismutase. 1 hit. SSF54719. SODismutase. 1 hit.
PROSITE	PS00088. SOD_MN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20811043.

Entry information

Entry name

Q6P980_DANRE

Accession

Primary (citable) accession number: Q6P980

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 29, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)