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Protein
Submitted name:

Pulmonary surfactant-associated protein C

Gene

Sftpc

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-5683826. Surfactant metabolism.

Names & Taxonomyi

Protein namesi
Submitted name:
Pulmonary surfactant-associated protein CImported
Submitted name:
Surfactant associated protein CImported
Gene namesi
Name:SftpcImported
ORF Names:mCG_16186Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:109517. Sftpc.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei36 – 5823HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000022097.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022692.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini94 – 193100BRICHOSInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IY85. Eukaryota.
ENOG41118MZ. LUCA.
GeneTreeiENSGT00390000017162.
HOVERGENiHBG000160.
OMAiLGQEEGH.
OrthoDBiEOG091G0P1Q.
TreeFamiTF337317.

Family and domain databases

InterProiIPR007084. BRICHOS_dom.
IPR001729. SP-C.
IPR018051. SP-C_palmitoylation_site.
IPR015091. Surfactant_protein_propep.
[Graphical view]
PfamiPF04089. BRICHOS. 1 hit.
PF08999. SP_C-Propep. 1 hit.
[Graphical view]
SMARTiSM01039. BRICHOS. 1 hit.
SM00019. SF_P. 1 hit.
[Graphical view]
PROSITEiPS50869. BRICHOS. 1 hit.
PS00341. SURFACT_PALMITOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P8P8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMSSKEVLM ESPPDYSAGP RSQFRIPCCP VHLKRLLIVV VVVVLVVVVI
60 70 80 90 100
VGALLMGLHM SQKHTEMVLE MSIGAPETQK RLAPSERADT IATFSIGSTG
110 120 130 140 150
IVVYDYQRLL TAYKPAPGTY CYIMKMAPES IPSLEAFARK LQNFQAKPST
160 170 180 190
PTSKLGQEEG HDTGSESDSS GRDLAFLGLA VSTLCGELPL YYI
Length:193
Mass (Da):21,027
Last modified:July 5, 2004 - v1
Checksum:i1287B4AC19AC8301
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122268 Genomic DNA. No translation available.
BC061137 mRNA. Translation: AAH61137.1.
CH466535 Genomic DNA. Translation: EDL35896.1.
RefSeqiNP_035489.2. NM_011359.2.
UniGeneiMm.24040.

Genome annotation databases

EnsembliENSMUST00000022692; ENSMUSP00000022692; ENSMUSG00000022097.
GeneIDi20389.
KEGGimmu:20389.
UCSCiuc007uoe.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122268 Genomic DNA. No translation available.
BC061137 mRNA. Translation: AAH61137.1.
CH466535 Genomic DNA. Translation: EDL35896.1.
RefSeqiNP_035489.2. NM_011359.2.
UniGeneiMm.24040.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022692.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022692; ENSMUSP00000022692; ENSMUSG00000022097.
GeneIDi20389.
KEGGimmu:20389.
UCSCiuc007uoe.2. mouse.

Organism-specific databases

CTDi6440.
MGIiMGI:109517. Sftpc.

Phylogenomic databases

eggNOGiENOG410IY85. Eukaryota.
ENOG41118MZ. LUCA.
GeneTreeiENSGT00390000017162.
HOVERGENiHBG000160.
OMAiLGQEEGH.
OrthoDBiEOG091G0P1Q.
TreeFamiTF337317.

Enzyme and pathway databases

ReactomeiR-MMU-5683826. Surfactant metabolism.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022097.

Family and domain databases

InterProiIPR007084. BRICHOS_dom.
IPR001729. SP-C.
IPR018051. SP-C_palmitoylation_site.
IPR015091. Surfactant_protein_propep.
[Graphical view]
PfamiPF04089. BRICHOS. 1 hit.
PF08999. SP_C-Propep. 1 hit.
[Graphical view]
SMARTiSM01039. BRICHOS. 1 hit.
SM00019. SF_P. 1 hit.
[Graphical view]
PROSITEiPS50869. BRICHOS. 1 hit.
PS00341. SURFACT_PALMITOYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P8P8_MOUSE
AccessioniPrimary (citable) accession number: Q6P8P8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.