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Q6P8P8

- Q6P8P8_MOUSE

UniProt

Q6P8P8 - Q6P8P8_MOUSE

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Protein
Submitted name:

Pulmonary surfactant-associated protein C

Gene
Sftpc, mCG_16186
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. cellular response to mechanical stimulus Source: Ensembl
  2. cellular response to nitric oxide Source: Ensembl
  3. circadian rhythm Source: Ensembl
  4. protein homooligomerization Source: Ensembl
  5. respiratory gaseous exchange Source: InterPro
  6. response to cAMP Source: Ensembl
  7. response to glucocorticoid Source: Ensembl
  8. response to glucose Source: Ensembl
  9. response to growth factor Source: Ensembl
  10. response to hyperoxia Source: Ensembl
  11. response to interleukin-6 Source: Ensembl
  12. response to lipopolysaccharide Source: Ensembl
  13. response to retinoic acid Source: Ensembl
  14. response to vitamin A Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Pulmonary surfactant-associated protein CImported
Submitted name:
Surfactant associated protein CImported
Gene namesi
Name:SftpcImported
ORF Names:mCG_16186Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:109517. Sftpc.

Subcellular locationi

GO - Cellular componenti

  1. alveolar lamellar body Source: Ensembl
  2. cytoplasm Source: MGI
  3. extracellular region Source: MGI
  4. extracellular space Source: Ensembl
  5. multivesicular body Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ6P8P8.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000017162.
HOVERGENiHBG000160.
InParanoidiQ6P8P8.
OMAiLGQEEGH.
OrthoDBiEOG7QVM46.
TreeFamiTF337317.

Family and domain databases

InterProiIPR007084. BRICHOS_dom.
IPR001729. Pulm_surfact_AP.
IPR018051. SP-C_palmitoylation_site.
IPR015091. Surfactant_protein_propep.
[Graphical view]
PfamiPF04089. BRICHOS. 1 hit.
PF08999. SP_C-Propep. 1 hit.
[Graphical view]
SMARTiSM01039. BRICHOS. 1 hit.
SM00019. SF_P. 1 hit.
[Graphical view]
PROSITEiPS50869. BRICHOS. 1 hit.
PS00341. SURFACT_PALMITOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P8P8-1 [UniParc]FASTAAdd to Basket

« Hide

MDMSSKEVLM ESPPDYSAGP RSQFRIPCCP VHLKRLLIVV VVVVLVVVVI    50
VGALLMGLHM SQKHTEMVLE MSIGAPETQK RLAPSERADT IATFSIGSTG 100
IVVYDYQRLL TAYKPAPGTY CYIMKMAPES IPSLEAFARK LQNFQAKPST 150
PTSKLGQEEG HDTGSESDSS GRDLAFLGLA VSTLCGELPL YYI 193
Length:193
Mass (Da):21,027
Last modified:July 5, 2004 - v1
Checksum:i1287B4AC19AC8301
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC122268 Genomic DNA. No translation available.
BC061137 mRNA. Translation: AAH61137.1.
CH466535 Genomic DNA. Translation: EDL35896.1.
RefSeqiNP_035489.2. NM_011359.2.
UniGeneiMm.24040.

Genome annotation databases

EnsembliENSMUST00000022692; ENSMUSP00000022692; ENSMUSG00000022097.
GeneIDi20389.
KEGGimmu:20389.
UCSCiuc007uoe.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC122268 Genomic DNA. No translation available.
BC061137 mRNA. Translation: AAH61137.1 .
CH466535 Genomic DNA. Translation: EDL35896.1 .
RefSeqi NP_035489.2. NM_011359.2.
UniGenei Mm.24040.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000022692 ; ENSMUSP00000022692 ; ENSMUSG00000022097 .
GeneIDi 20389.
KEGGi mmu:20389.
UCSCi uc007uoe.2. mouse.

Organism-specific databases

CTDi 6440.
MGIi MGI:109517. Sftpc.

Phylogenomic databases

GeneTreei ENSGT00390000017162.
HOVERGENi HBG000160.
InParanoidi Q6P8P8.
OMAi LGQEEGH.
OrthoDBi EOG7QVM46.
TreeFami TF337317.

Miscellaneous databases

NextBioi 298322.
SOURCEi Search...

Gene expression databases

Genevestigatori Q6P8P8.

Family and domain databases

InterProi IPR007084. BRICHOS_dom.
IPR001729. Pulm_surfact_AP.
IPR018051. SP-C_palmitoylation_site.
IPR015091. Surfactant_protein_propep.
[Graphical view ]
Pfami PF04089. BRICHOS. 1 hit.
PF08999. SP_C-Propep. 1 hit.
[Graphical view ]
SMARTi SM01039. BRICHOS. 1 hit.
SM00019. SF_P. 1 hit.
[Graphical view ]
PROSITEi PS50869. BRICHOS. 1 hit.
PS00341. SURFACT_PALMITOYL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Lung and heartImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ6P8P8_MOUSE
AccessioniPrimary (citable) accession number: Q6P8P8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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