Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6P8P8

- Q6P8P8_MOUSE

UniProt

Q6P8P8 - Q6P8P8_MOUSE

Protein
Submitted name:

Pulmonary surfactant-associated protein C

Gene

Sftpc

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Biological processi

    1. cellular response to mechanical stimulus Source: Ensembl
    2. cellular response to nitric oxide Source: Ensembl
    3. circadian rhythm Source: Ensembl
    4. protein homooligomerization Source: Ensembl
    5. respiratory gaseous exchange Source: InterPro
    6. response to cAMP Source: Ensembl
    7. response to glucocorticoid Source: Ensembl
    8. response to glucose Source: Ensembl
    9. response to growth factor Source: Ensembl
    10. response to hyperoxia Source: Ensembl
    11. response to interleukin-6 Source: Ensembl
    12. response to lipopolysaccharide Source: Ensembl
    13. response to retinoic acid Source: Ensembl
    14. response to vitamin A Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Pulmonary surfactant-associated protein CImported
    Submitted name:
    Surfactant associated protein CImported
    Gene namesi
    Name:SftpcImported
    ORF Names:mCG_16186Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:109517. Sftpc.

    Subcellular locationi

    GO - Cellular componenti

    1. alveolar lamellar body Source: Ensembl
    2. cytoplasm Source: MGI
    3. extracellular region Source: MGI
    4. extracellular space Source: Ensembl
    5. multivesicular body Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriQ6P8P8.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000017162.
    HOVERGENiHBG000160.
    InParanoidiQ6P8P8.
    OMAiLGQEEGH.
    OrthoDBiEOG7QVM46.
    TreeFamiTF337317.

    Family and domain databases

    InterProiIPR007084. BRICHOS_dom.
    IPR001729. Pulm_surfact_AP.
    IPR018051. SP-C_palmitoylation_site.
    IPR015091. Surfactant_protein_propep.
    [Graphical view]
    PfamiPF04089. BRICHOS. 1 hit.
    PF08999. SP_C-Propep. 1 hit.
    [Graphical view]
    SMARTiSM01039. BRICHOS. 1 hit.
    SM00019. SF_P. 1 hit.
    [Graphical view]
    PROSITEiPS50869. BRICHOS. 1 hit.
    PS00341. SURFACT_PALMITOYL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6P8P8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDMSSKEVLM ESPPDYSAGP RSQFRIPCCP VHLKRLLIVV VVVVLVVVVI    50
    VGALLMGLHM SQKHTEMVLE MSIGAPETQK RLAPSERADT IATFSIGSTG 100
    IVVYDYQRLL TAYKPAPGTY CYIMKMAPES IPSLEAFARK LQNFQAKPST 150
    PTSKLGQEEG HDTGSESDSS GRDLAFLGLA VSTLCGELPL YYI 193
    Length:193
    Mass (Da):21,027
    Last modified:July 5, 2004 - v1
    Checksum:i1287B4AC19AC8301
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC122268 Genomic DNA. No translation available.
    BC061137 mRNA. Translation: AAH61137.1.
    CH466535 Genomic DNA. Translation: EDL35896.1.
    RefSeqiNP_035489.2. NM_011359.2.
    UniGeneiMm.24040.

    Genome annotation databases

    EnsembliENSMUST00000022692; ENSMUSP00000022692; ENSMUSG00000022097.
    GeneIDi20389.
    KEGGimmu:20389.
    UCSCiuc007uoe.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC122268 Genomic DNA. No translation available.
    BC061137 mRNA. Translation: AAH61137.1 .
    CH466535 Genomic DNA. Translation: EDL35896.1 .
    RefSeqi NP_035489.2. NM_011359.2.
    UniGenei Mm.24040.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000022692 ; ENSMUSP00000022692 ; ENSMUSG00000022097 .
    GeneIDi 20389.
    KEGGi mmu:20389.
    UCSCi uc007uoe.2. mouse.

    Organism-specific databases

    CTDi 6440.
    MGIi MGI:109517. Sftpc.

    Phylogenomic databases

    GeneTreei ENSGT00390000017162.
    HOVERGENi HBG000160.
    InParanoidi Q6P8P8.
    OMAi LGQEEGH.
    OrthoDBi EOG7QVM46.
    TreeFami TF337317.

    Miscellaneous databases

    NextBioi 298322.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q6P8P8.

    Family and domain databases

    InterProi IPR007084. BRICHOS_dom.
    IPR001729. Pulm_surfact_AP.
    IPR018051. SP-C_palmitoylation_site.
    IPR015091. Surfactant_protein_propep.
    [Graphical view ]
    Pfami PF04089. BRICHOS. 1 hit.
    PF08999. SP_C-Propep. 1 hit.
    [Graphical view ]
    SMARTi SM01039. BRICHOS. 1 hit.
    SM00019. SF_P. 1 hit.
    [Graphical view ]
    PROSITEi PS50869. BRICHOS. 1 hit.
    PS00341. SURFACT_PALMITOYL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Lung and heartImported.
    3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    5. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ6P8P8_MOUSE
    AccessioniPrimary (citable) accession number: Q6P8P8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3