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Q6P824 (GPD1L_XENTR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase 1-like protein

EC=1.1.1.8
Gene names
Name:gpd1l
OrganismXenopus tropicalis (Western clawed frog) (Silurana tropicalis) [Reference proteome]
Taxonomic identifier8364 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Plays a role in regulating cardiac sodium current By similarity.

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 352352Glycerol-3-phosphate dehydrogenase 1-like protein
PRO_0000286516

Regions

Nucleotide binding13 – 186NAD By similarity
Region272 – 2732Substrate binding By similarity

Sites

Active site2071Proton acceptor By similarity
Binding site441NAD By similarity
Binding site1001NAD By similarity
Binding site1231Substrate By similarity
Binding site1561NAD; via amide nitrogen By similarity
Binding site2721NAD By similarity
Binding site2991NAD; via amide nitrogen By similarity
Binding site3011NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6P824 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 2E08E289DCF0A934

FASTA35238,464
        10         20         30         40         50         60 
MALAGPLKVC IVGSGNWGSA VAKIIGHNVK NLKKFASTVN MWVFEENING RKLTEIINTE 

        70         80         90        100        110        120 
HENVKYLPGY KLPENVVAVP NLSDAVKDAD LLIFVIPHQF IHKICQEISG KVHRNALGIT 

       130        140        150        160        170        180 
LIKGIDEGPE GLRLISDIIR EKMDIDVSVL MGANIANEVA AEKFCETTIG SKNKEHGLLF 

       190        200        210        220        230        240 
KELLQTPNFR ITVVEDADTV ELCGALKNIV AVAAGFCDGL GCGDNTKAAV IRLGLMEMIA 

       250        260        270        280        290        300 
FANVFCKGPV SIATFLESCG VADLITTCYG GRNRKVSEAF VKSGKSIEEL EKEMLNGQKL 

       310        320        330        340        350 
QGPQTSAEVY RILQQKNMVN KFPLFTAVYQ ICYEGKPVED VISCLQSHPE HM 

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC061407 mRNA. Translation: AAH61407.1.
RefSeqNP_989027.1. NM_203696.1.
UniGeneStr.4931.

3D structure databases

ProteinModelPortalQ6P824.
SMRQ6P824. Positions 5-347.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING8364.ENSXETP00000032859.

Proteomic databases

PRIDEQ6P824.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSXETT00000032859; ENSXETP00000032859; ENSXETG00000015022.
GeneID394623.
KEGGxtr:394623.

Organism-specific databases

CTD23171.
XenbaseXB-GENE-969902. gpd1l.

Phylogenomic databases

eggNOGCOG0240.
GeneTreeENSGT00390000003114.
HOGENOMHOG000246855.
HOVERGENHBG003669.
InParanoidQ6P824.
KOK00006.
OMAFMEGICK.
OrthoDBEOG7ZKSBS.
TreeFamTF300836.

Gene expression databases

BgeeQ6P824.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. SSF48179. 1 hit.
TIGRFAMsTIGR03376. glycerol3P_DH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGPD1L_XENTR
AccessionPrimary (citable) accession number: Q6P824
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families