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Protein

Synaptobrevin homolog YKT6

Gene

ykt6

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. May function in endoplasmic reticulum to Golgi transport and endosomes to Golgi transport (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptobrevin homolog YKT6 (EC:2.3.1.-)
Gene namesi
Name:ykt6
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-949728. ykt6.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002807151 – 195Synaptobrevin homolog YKT6Add BLAST195
PropeptideiPRO_0000396667196 – 198Removed in mature formBy similarity3

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi194S-palmitoyl cysteineBy similarity1
Modified residuei195Cysteine methyl esterBy similarity1
Lipidationi195S-farnesyl cysteineBy similarity1

Post-translational modificationi

Palmitoylated; catalyzes its own palmitoylation. Palmitoylation is required for Golgi targeting (By similarity).By similarity
Farnesylation is required for Golgi targeting.By similarity

Keywords - PTMi

Lipoprotein, Methylation, Palmitate, Prenylation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ6P816.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 127LonginPROSITE-ProRule annotationAdd BLAST120
Domaini138 – 198v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST61

Domaini

The longin domain regulates palmitoylation and membrane targeting.By similarity

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated
Contains 1 longin domain.PROSITE-ProRule annotation
Contains 1 v-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000189970.
HOVERGENiHBG088939.
InParanoidiQ6P816.
KOiK08516.

Family and domain databases

Gene3Di3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6P816-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLYSLSVLY KGDNKVSLLK SAYDVSSFSF FQRSSIQEFM AFTSQLIVER
60 70 80 90 100
SDKGSRSSVK EQEYLCHVYV RNDSLAGVVI ADNEYPPRVC FTLLEKVLEE
110 120 130 140 150
FSTQVDRIDW PSGSPATIQY NALDSYLSKY QNPRDADPMS KVQAELDETK
160 170 180 190
IILHNTMESL LQRGEKLDDL VSKSEVLGTQ SKAFYKTARK QNSCCGIM
Length:198
Mass (Da):22,488
Last modified:July 5, 2004 - v1
Checksum:i13CBD1023DFAC334
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061415 mRNA. Translation: AAH61415.1.
RefSeqiNP_989023.1. NM_203692.1.
XP_012814209.1. XM_012958755.2.
UniGeneiStr.7551.

Genome annotation databases

GeneIDi394619.
KEGGixtr:394619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061415 mRNA. Translation: AAH61415.1.
RefSeqiNP_989023.1. NM_203692.1.
XP_012814209.1. XM_012958755.2.
UniGeneiStr.7551.

3D structure databases

ProteinModelPortaliQ6P816.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi394619.
KEGGixtr:394619.

Organism-specific databases

CTDi10652.
XenbaseiXB-GENE-949728. ykt6.

Phylogenomic databases

HOGENOMiHOG000189970.
HOVERGENiHBG088939.
InParanoidiQ6P816.
KOiK08516.

Family and domain databases

Gene3Di3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYKT6_XENTR
AccessioniPrimary (citable) accession number: Q6P816
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.