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Protein

Structural maintenance of chromosomes protein

Gene

Smc4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Structural maintenance of chromosomes proteinUniRule annotation
Gene namesi
Name:Smc4Imported
Synonyms:Smc4l1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1917349. Smc4.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ6P7V9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000034349.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047872.

Structurei

3D structure databases

ProteinModelPortaliQ6P7V9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini541 – 656116SMC_hingeInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili325 – 35935Sequence analysisAdd
BLAST
Coiled coili367 – 41246Sequence analysisAdd
BLAST
Coiled coili469 – 50335Sequence analysisAdd
BLAST
Coiled coili704 – 73128Sequence analysisAdd
BLAST
Coiled coili820 – 938119Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the SMC family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0996. Eukaryota.
COG1196. LUCA.
HOGENOMiHOG000184777.
HOVERGENiHBG106696.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
IPR024704. SMC.
IPR010935. SMC_hinge.
[Graphical view]
PfamiPF06470. SMC_hinge. 1 hit.
PF02463. SMC_N. 1 hit.
[Graphical view]
PIRSFiPIRSF005719. SMC. 1 hit.
SMARTiSM00968. SMC_hinge. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF75553. SSF75553. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6P7V9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASEAGAPRL MITHIVNQNF KSYAGEKVLG PFHKRFSCII GPNGSGKSNV
60 70 80 90 100
IDSMLFVFGY RAQKIRSKKL SVLIHNSDEH KDIQSCTVEV HFQKIIDKEG
110 120 130 140 150
DDYEVLPNSN FYVSRTAYRD STSVYHISGK KKTFKDVGNL LRSHGIDLDH
160 170 180 190 200
NRFLILQGEV EQIAMMKPKG QTEHDEGMLE YLEDIIGCGR LNEPIKVLCR
210 220 230 240 250
RVEILNEHRG EKLNRVKMVE KEKDALEGEK NIAIEFLTLE NEMFKKKNHI
260 270 280 290 300
CQYYIYDLQN RIAEITTQKE KIHEDTKEIT EKSNVLSNEM KAKNSAVKDV
310 320 330 340 350
EKKLNKVTKF IEQNKEKFTQ LDLEDVQVRE KLKHATSKAK KLEKQLQKDK
360 370 380 390 400
EKVEELKSVP AKSKTVINET TTRNNSLEKE REKEEKKLKE VMDSLKQETQ
410 420 430 440 450
GLQKEKEIQE KELMGFNKSV NEARSKMEVA QSELDIYLSR HNTAVSQLSK
460 470 480 490 500
AKEALITASE TLKERKAAIK DINTKLPQTQ QELKEKEKEL QKLTQEEINL
510 520 530 540 550
KSLVHDLFQK VEEAKSSLAM NRSRGKVLDA IIQEKKSGRI PGIYGRLGDL
560 570 580 590 600
GAIDEKYDIA ISSCCHALDY IVVDSIDTAQ ECVNFLKKHN IGIATFIGLD
610 620 630 640 650
KMTVWAKKMS KIQTPENTPR LFDLVKVKNE EIRQAFYFAL RDTLVANNLD
660 670 680 690 700
QATRVAYQRD RRWRVVTLQG QIIEQSGTMS GGGSKVMRGR MGSSVIDEIS
710 720 730 740 750
VEEVNKMESQ LERHSKQAMQ IQEQKVQHEE AVVKLRHSER DMRNTLEKFA
760 770 780 790 800
ASIQGLSEQE EYLCVQIKEL EANVLTTAPD RKQQKLLEEN VSVFKKEYDA
810 820 830 840 850
VAEKAGKVEA EIKRLHNTII DINNRKLKAQ QNKLDTINKQ LDECASAITK
860 870 880 890 900
AQVAIKTADR NLKKAQDSVC RTEKEIKDTE KEINDLKTEL KNIEDKAEEV
910 920 930 940 950
INNTKTAETS LPEIQKEHRN LLQELKVIQE NEHALQKDAL SIKLKLEQID
960 970 980 990 1000
GHISEHNSKI KYWQKEISKI KLHPVEDNPV ETVAVLSQEE LEAIKNPESI
1010 1020 1030 1040 1050
TNEIALLEAQ CREMKPNLGA IAEYKKKEDL YLQRVAELDK ITSERDNFRQ
1060 1070 1080 1090 1100
AYEDLRKQRL NEFMAGFYVI TNKLKENYQM LTLGGDAELE LVDSLDPFSE
1110 1120 1130 1140 1150
GIMFSVRPPK KSWKKIFNLS GGEKTLSSLA LVFALHHYKP TPLYFMDEID
1160 1170 1180 1190 1200
AALDFKNVSI VAFYIYEQTK NAQFIIISLR NNMFEISDRL IGIYKTYNST
1210
KSVAVNPKQI ASKGLC
Length:1,216
Mass (Da):139,520
Last modified:July 5, 2004 - v1
Checksum:iB3F8C45521ECFB92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061481 mRNA. Translation: AAH61481.1.
RefSeqiXP_006502110.1. XM_006502047.2.
UniGeneiMm.206841.

Genome annotation databases

GeneIDi70099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061481 mRNA. Translation: AAH61481.1.
RefSeqiXP_006502110.1. XM_006502047.2.
UniGeneiMm.206841.

3D structure databases

ProteinModelPortaliQ6P7V9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047872.

Proteomic databases

PaxDbiQ6P7V9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi70099.

Organism-specific databases

CTDi10051.
MGIiMGI:1917349. Smc4.

Phylogenomic databases

eggNOGiKOG0996. Eukaryota.
COG1196. LUCA.
HOGENOMiHOG000184777.
HOVERGENiHBG106696.

Miscellaneous databases

ChiTaRSiSmc4. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034349.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
IPR024704. SMC.
IPR010935. SMC_hinge.
[Graphical view]
PfamiPF06470. SMC_hinge. 1 hit.
PF02463. SMC_N. 1 hit.
[Graphical view]
PIRSFiPIRSF005719. SMC. 1 hit.
SMARTiSM00968. SMC_hinge. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF75553. SSF75553. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P7V9_MOUSE
AccessioniPrimary (citable) accession number: Q6P7V9
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.