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Protein
Submitted name:

Ephrin B1

Gene

Efnb1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-2682334. EPH-Ephrin signaling.
R-RNO-3928662. EPHB-mediated forward signaling.
R-RNO-3928664. Ephrin signaling.
R-RNO-3928665. EPH-ephrin mediated repulsion of cells.

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin B1Imported
Submitted name:
Ephrin B1, isoform CRA_aImported
Submitted name:
Ephrin-B1Imported
Gene namesi
Name:Efnb1Imported
ORF Names:rCG_36210Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi2540. Efnb1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei237 – 262HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500878269925 – 345Sequence analysisAdd BLAST321

Expressioni

Gene expression databases

BgeeiENSRNOG00000006877.

Interactioni

Protein-protein interaction databases

DIPiDIP-464N.
STRINGi10116.ENSRNOP00000009635.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 164Ephrin RBD (ephrin receptor-binding)InterPro annotationAdd BLAST135

Sequence similaritiesi

Belongs to the ephrin family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3858. Eukaryota.
ENOG4111FMJ. LUCA.
GeneTreeiENSGT00390000005839.
HOVERGENiHBG051448.
KOiK05463.
OMAiWALCRLA.
OrthoDBiEOG091G0BPC.

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR031328. Ephrin.
IPR019765. Ephrin_CS.
IPR001799. Ephrin_RBD.
[Graphical view]
PANTHERiPTHR11304. PTHR11304. 1 hit.
PfamiPF00812. Ephrin. 1 hit.
[Graphical view]
PRINTSiPR01347. EPHRIN.
ProDomiPD002533. Ephrin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiPS01299. EPHRIN_RBD_1. 1 hit.
PS51551. EPHRIN_RBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P7B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARPGQRWLS KWLVAMVVLT LCRLATPLAK NLEPVSWSSL NPKFLSGKGL
60 70 80 90 100
VIYPKIGDKL DIICPRAEAG RPYEYYKLYL VRPEQAAACS TVLDPNVLVT
110 120 130 140 150
CNKPQQEIRF TIKFQEFSPN YMGLEFKKYH DYYITSTSNG SLEGLENREG
160 170 180 190 200
GVCRTRTMKI VMKVGQDPNA VTPEQLTTSR PSKESDNTVK TATQAPGRGS
210 220 230 240 250
QGDSDGKHET VNQQEKSGPG AGGSGSGDTD SFFNSKVALF AAVGAGCVIF
260 270 280 290 300
LLIIIFLTVL LLKLRKRHRK HTQQRAAALS LSTLASPKGG SGTAGTEPSD
310 320 330 340
IIIPLRTTEN NYCPHYEKVS GDYGHPVYIV QEMPPQSPAN IYYKV
Length:345
Mass (Da):37,893
Last modified:July 5, 2004 - v1
Checksum:i783046C6C7358F7C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07039133 Genomic DNA. No translation available.
BC061744 mRNA. Translation: AAH61744.1.
CH473966 Genomic DNA. Translation: EDL95949.1.
CH473966 Genomic DNA. Translation: EDL95950.1.
RefSeqiNP_058785.2. NM_017089.2.
UniGeneiRn.44398.

Genome annotation databases

EnsembliENSRNOT00000009635; ENSRNOP00000009635; ENSRNOG00000006877.
GeneIDi25186.
KEGGirno:25186.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07039133 Genomic DNA. No translation available.
BC061744 mRNA. Translation: AAH61744.1.
CH473966 Genomic DNA. Translation: EDL95949.1.
CH473966 Genomic DNA. Translation: EDL95950.1.
RefSeqiNP_058785.2. NM_017089.2.
UniGeneiRn.44398.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-464N.
STRINGi10116.ENSRNOP00000009635.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000009635; ENSRNOP00000009635; ENSRNOG00000006877.
GeneIDi25186.
KEGGirno:25186.

Organism-specific databases

CTDi1947.
RGDi2540. Efnb1.

Phylogenomic databases

eggNOGiKOG3858. Eukaryota.
ENOG4111FMJ. LUCA.
GeneTreeiENSGT00390000005839.
HOVERGENiHBG051448.
KOiK05463.
OMAiWALCRLA.
OrthoDBiEOG091G0BPC.

Enzyme and pathway databases

ReactomeiR-RNO-2682334. EPH-Ephrin signaling.
R-RNO-3928662. EPHB-mediated forward signaling.
R-RNO-3928664. Ephrin signaling.
R-RNO-3928665. EPH-ephrin mediated repulsion of cells.

Gene expression databases

BgeeiENSRNOG00000006877.

Family and domain databases

Gene3Di2.60.40.420. 1 hit.
InterProiIPR008972. Cupredoxin.
IPR031328. Ephrin.
IPR019765. Ephrin_CS.
IPR001799. Ephrin_RBD.
[Graphical view]
PANTHERiPTHR11304. PTHR11304. 1 hit.
PfamiPF00812. Ephrin. 1 hit.
[Graphical view]
PRINTSiPR01347. EPHRIN.
ProDomiPD002533. Ephrin. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF49503. SSF49503. 1 hit.
PROSITEiPS01299. EPHRIN_RBD_1. 1 hit.
PS51551. EPHRIN_RBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P7B6_RAT
AccessioniPrimary (citable) accession number: Q6P7B6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.