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Protein

Protein FAM198B

Gene

Fam198b

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM198B
Alternative name(s):
Expressed in nerve and epithelium during development
Gene namesi
Name:Fam198b
Synonyms:Ened
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 2

Organism-specific databases

RGDi735075. Fam198b.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3737CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei38 – 5518Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST
Topological domaini56 – 516461ExtracellularSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. Golgi membrane Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 516516Protein FAM198BPRO_0000288904Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi286 – 2861N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ6P7B4.

Expressioni

Gene expression databases

GenevestigatoriQ6P7B4.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000013525.

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM198 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG44675.
GeneTreeiENSGT00420000029769.
HOGENOMiHOG000112372.
InParanoidiQ6P7B4.
OMAiKVGERPW.
OrthoDBiEOG76DTS4.
PhylomeDBiQ6P7B4.
TreeFamiTF330994.

Family and domain databases

InterProiIPR029207. FAM198.
[Graphical view]
PfamiPF15051. FAM198. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P7B4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTCPDKLGQL INWFVCSLCA PRVCKLWSSR RPRTRRNLLL GTACAIYLGF
60 70 80 90 100
LVSQVGKGSF QHGQATNRGP PNNQDIFKVP FPEIPLDGTL APPESQGNGS
110 120 130 140 150
TLQPNVVYIT LRSKRSKPAN IRGTVKPKRR KKYAVASVAP DQEVLVRPSL
160 170 180 190 200
IQPEVARAAD AEVPGYVQGY LTKVGERPWR MLHGPRVRGS NLQQPRAPES
210 220 230 240 250
NIRIYSESAP SWLSKEDIRR MRLLADGEVA SILPTIFEGG TRLLMLEGST
260 270 280 290 300
SGSVPGCGPS PCGLLKQPLD MSEVFAFHLD RILGLNRTLP SVSRKLEFIQ
310 320 330 340 350
DGRPRPIILW DSSLVPSSNV SHSSVKITWG TYQQLLKQKC WLNGRVPRPE
360 370 380 390 400
WGCTEVHHHE WSKMALFDFL LQIYNRLDTN CCGFRPRKED ACVQNGLRPN
410 420 430 440 450
CEDQSSVTLA HIIQRKNDPR HLVFINNKGF FDRSEDNLNF KLLEGIREFP
460 470 480 490 500
ESAVSVLKSQ HLRQKLLQSL FLDQVYWESQ GGRQGIEKLI DVIERRARIL
510
ITYINAHGAR VLPMNE
Length:516
Mass (Da):58,206
Last modified:July 5, 2004 - v1
Checksum:iCBF1FCD4340CBA6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061747 mRNA. Translation: AAH61747.1.
RefSeqiNP_954536.1. NM_199105.1.
XP_006232576.1. XM_006232514.2.
UniGeneiRn.20514.

Genome annotation databases

EnsembliENSRNOT00000013524; ENSRNOP00000013525; ENSRNOG00000010183.
GeneIDi310540.
KEGGirno:310540.
UCSCiRGD:735075. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061747 mRNA. Translation: AAH61747.1.
RefSeqiNP_954536.1. NM_199105.1.
XP_006232576.1. XM_006232514.2.
UniGeneiRn.20514.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000013525.

Proteomic databases

PRIDEiQ6P7B4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000013524; ENSRNOP00000013525; ENSRNOG00000010183.
GeneIDi310540.
KEGGirno:310540.
UCSCiRGD:735075. rat.

Organism-specific databases

CTDi51313.
RGDi735075. Fam198b.

Phylogenomic databases

eggNOGiNOG44675.
GeneTreeiENSGT00420000029769.
HOGENOMiHOG000112372.
InParanoidiQ6P7B4.
OMAiKVGERPW.
OrthoDBiEOG76DTS4.
PhylomeDBiQ6P7B4.
TreeFamiTF330994.

Miscellaneous databases

NextBioi662125.
PROiQ6P7B4.

Gene expression databases

GenevestigatoriQ6P7B4.

Family and domain databases

InterProiIPR029207. FAM198.
[Graphical view]
PfamiPF15051. FAM198. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.

Entry informationi

Entry nameiF198B_RAT
AccessioniPrimary (citable) accession number: Q6P7B4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: July 5, 2004
Last modified: January 7, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.