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Protein

Proteolipid protein 2

Gene

Plp2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in cell differentiation in the intestinal epithelium.By similarity

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Proteolipid protein 2
Gene namesi
Name:Plp2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi1587363 Plp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Transmembranei112 – 132HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001568221 – 151Proteolipid protein 2Add BLAST151

Proteomic databases

PaxDbiQ6P742
PRIDEiQ6P742

Expressioni

Gene expression databases

BgeeiENSRNOG00000039496
GenevisibleiQ6P742 RN

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000039462

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 137MARVELPROSITE-ProRule annotationAdd BLAST119

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4788 Eukaryota
ENOG4111IAF LUCA
GeneTreeiENSGT00530000063326
HOGENOMiHOG000293179
HOVERGENiHBG099247
InParanoidiQ6P742
OMAiIYMCDLH
OrthoDBiEOG091G0SSY
PhylomeDBiQ6P742
TreeFamiTF317387

Family and domain databases

InterProiView protein in InterPro
IPR008253 Marvel
PfamiView protein in Pfam
PF01284 MARVEL, 1 hit
PROSITEiView protein in PROSITE
PS51225 MARVEL, 1 hit

Sequencei

Sequence statusi: Complete.

Q6P742-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSERLSAP GCWLACTSFS RTKKGILLFA EIILCLVILI CFSASTSAYS
60 70 80 90 100
SLSVIEMIFA AVLFVFYMCD LHSKISFINW PWTDFFRSLI AAILYLITSI
110 120 130 140 150
VVLVEGRGSS KIVAGVLGLL ATLLFGYDAY ITFPLKQQRH TAAPTDPTDG

P
Length:151
Mass (Da):16,557
Last modified:July 5, 2004 - v1
Checksum:i696489C90C58FAE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061844 mRNA Translation: AAH61844.1
RefSeqiNP_997484.1, NM_207601.1
UniGeneiRn.96974

Genome annotation databases

EnsembliENSRNOT00000045256; ENSRNOP00000039462; ENSRNOG00000039496
GeneIDi302562
KEGGirno:302562
UCSCiRGD:1587363 rat

Similar proteinsi

Entry informationi

Entry nameiPLP2_RAT
AccessioniPrimary (citable) accession number: Q6P742
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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