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Protein

Proteolipid protein 2

Gene

Plp2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in cell differentiation in the intestinal epithelium.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Proteolipid protein 2
Gene namesi
Name:Plp2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi1587363. Plp2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei25 – 4521HelicalSequence analysisAdd
BLAST
Transmembranei48 – 6821HelicalSequence analysisAdd
BLAST
Transmembranei85 – 10521HelicalSequence analysisAdd
BLAST
Transmembranei112 – 13221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151Proteolipid protein 2PRO_0000156822Add
BLAST

Proteomic databases

PaxDbiQ6P742.
PRIDEiQ6P742.

Expressioni

Gene expression databases

BgeeiENSRNOG00000039496.
GenevisibleiQ6P742. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000039462.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 137119MARVELPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 MARVEL domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4788. Eukaryota.
ENOG4111IAF. LUCA.
GeneTreeiENSGT00530000063326.
HOGENOMiHOG000293179.
HOVERGENiHBG099247.
InParanoidiQ6P742.
OMAiIYMCDLH.
OrthoDBiEOG091G0SSY.
PhylomeDBiQ6P742.
TreeFamiTF317387.

Family and domain databases

InterProiIPR008253. Marvel.
[Graphical view]
PfamiPF01284. MARVEL. 1 hit.
[Graphical view]
PROSITEiPS51225. MARVEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P742-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSERLSAP GCWLACTSFS RTKKGILLFA EIILCLVILI CFSASTSAYS
60 70 80 90 100
SLSVIEMIFA AVLFVFYMCD LHSKISFINW PWTDFFRSLI AAILYLITSI
110 120 130 140 150
VVLVEGRGSS KIVAGVLGLL ATLLFGYDAY ITFPLKQQRH TAAPTDPTDG

P
Length:151
Mass (Da):16,557
Last modified:July 5, 2004 - v1
Checksum:i696489C90C58FAE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061844 mRNA. Translation: AAH61844.1.
RefSeqiNP_997484.1. NM_207601.1.
UniGeneiRn.96974.

Genome annotation databases

EnsembliENSRNOT00000045256; ENSRNOP00000039462; ENSRNOG00000039496.
GeneIDi302562.
KEGGirno:302562.
UCSCiRGD:1587363. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061844 mRNA. Translation: AAH61844.1.
RefSeqiNP_997484.1. NM_207601.1.
UniGeneiRn.96974.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000039462.

Proteomic databases

PaxDbiQ6P742.
PRIDEiQ6P742.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000045256; ENSRNOP00000039462; ENSRNOG00000039496.
GeneIDi302562.
KEGGirno:302562.
UCSCiRGD:1587363. rat.

Organism-specific databases

CTDi5355.
RGDi1587363. Plp2.

Phylogenomic databases

eggNOGiKOG4788. Eukaryota.
ENOG4111IAF. LUCA.
GeneTreeiENSGT00530000063326.
HOGENOMiHOG000293179.
HOVERGENiHBG099247.
InParanoidiQ6P742.
OMAiIYMCDLH.
OrthoDBiEOG091G0SSY.
PhylomeDBiQ6P742.
TreeFamiTF317387.

Miscellaneous databases

PROiQ6P742.

Gene expression databases

BgeeiENSRNOG00000039496.
GenevisibleiQ6P742. RN.

Family and domain databases

InterProiIPR008253. Marvel.
[Graphical view]
PfamiPF01284. MARVEL. 1 hit.
[Graphical view]
PROSITEiPS51225. MARVEL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPLP2_RAT
AccessioniPrimary (citable) accession number: Q6P742
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.