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Protein
Submitted name:

Polypyrimidine tract binding protein 1, isoform CRA_a

Gene

Ptbp1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-RNO-72163 mRNA Splicing - Major Pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Polypyrimidine tract binding protein 1, isoform CRA_aImported
Submitted name:
Polypyrimidine tract-binding protein 1Imported
Submitted name:
Ptbp1 proteinImported
Gene namesi
Name:Ptbp1Imported
ORF Names:rCG_29328Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi62047 Ptbp1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000010448

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini58 – 142RRMInterPro annotationAdd BLAST85
Domaini183 – 259RRMInterPro annotationAdd BLAST77
Domaini362 – 436RRMInterPro annotationAdd BLAST75
Domaini479 – 554RRMInterPro annotationAdd BLAST76

Phylogenomic databases

eggNOGiKOG1190 Eukaryota
ENOG410XPMZ LUCA
GeneTreeiENSGT00550000074508
HOGENOMiHOG000231699
HOVERGENiHBG069548
KOiK13218
OMAiSEECAQT
OrthoDBiEOG091G0Z5R
TreeFamiTF319824

Family and domain databases

CDDicd12777 RRM1_PTBP1, 1 hit
cd12693 RRM2_PTBP1_like, 1 hit
cd12695 RRM3_PTBP1, 1 hit
Gene3Di3.30.70.3304 hits
InterProiView protein in InterPro
IPR006536 HnRNP-L/PTB
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034798 PTBP1/2/3_RRM2
IPR035000 PTBP1_RRM1
IPR035001 PTBP1_RRM3
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 4 hits
SUPFAMiSSF54928 SSF54928, 4 hits
TIGRFAMsiTIGR01649 hnRNP-L_PTB, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 4 hits

Sequencei

Sequence statusi: Complete.

Q6P736-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGIVPDIAV GTKRGSDELF STCVSNGPFI MSSSASAANG NDSKKFKGDN
60 70 80 90 100
RSTGVPSRVI HVRKLPSDVT EGEVISLGLP FGKVTNLLML KGKNQAFIEM
110 120 130 140 150
STEEAANTMV NYYTSVAPVL RGQPIYIQFS NHKELKTDSS PNQARAQAAL
160 170 180 190 200
QAVNSVQSGN LALAASAAAV DAGMAMAGQS PVLRIIVENL FYPVTLDVLH
210 220 230 240 250
QIFSKFGTVL KIITFTKNNQ FQALLQYADP VSAQHAKLSL DGQNIYNACC
260 270 280 290 300
TLRIDFSKLT SLNVKYNNDK SRDYTRPDLP SGDSQPSLDQ TMAAAFGAPG
310 320 330 340 350
IMSASPYAGA GFPPTFAIPQ AAGLSVPNVH GALAPLAIPS AAAAAAAAGR
360 370 380 390 400
IAIPGLAGAG NSVLLVSNLN PERVTPQSLF ILFGVYGDVQ RVKILFNKKE
410 420 430 440 450
NALVQMADGS QAQLAMSHLN GHKLHGKSVR ITLSKHQSVQ LPREGQEDQG
460 470 480 490 500
LTKDYGSSPL HRFKKPGSKN FQNIFPPSAT LHLSNIPPSV SEDDLKSLFS
510 520 530 540 550
SNGGVVKGFK FFQKDRKMAL IQMGSVEEAV QALIELHNHD LGENHHLRVS

FSKSTI
Length:556
Mass (Da):59,366
Last modified:July 5, 2004 - v1
Checksum:i08A7E5D5EF7F3811
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07055846 Genomic DNA No translation available.
BC061858 mRNA Translation: AAH61858.1
CH474029 Genomic DNA Translation: EDL89384.1
RefSeqiNP_001257986.1, NM_001271057.1
NP_071961.2, NM_022516.5
UniGeneiRn.64440

Genome annotation databases

EnsembliENSRNOT00000044865; ENSRNOP00000043256; ENSRNOG00000010448
GeneIDi29497
KEGGirno:29497

Similar proteinsi

Entry informationi

Entry nameiQ6P736_RAT
AccessioniPrimary (citable) accession number: Q6P736
Secondary accession number(s): F1LM18
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported