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Protein

Protein GPR108

Gene

Gpr108

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein GPR108
Gene namesi
Name:Gpr108
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi735149. Gpr108.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei296 – 316Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei325 – 345Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei369 – 389Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei400 – 420Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei434 – 454Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei482 – 502Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei506 – 526Helical; Name=7Sequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 34Sequence analysisAdd BLAST34
ChainiPRO_000004508535 – 577Protein GPR108Add BLAST543

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi59N-linked (GlcNAc...)Sequence analysis1
Glycosylationi111N-linked (GlcNAc...)Sequence analysis1
Glycosylationi233N-linked (GlcNAc...)Sequence analysis1
Glycosylationi237N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ6P6V6.
PRIDEiQ6P6V6.

PTM databases

iPTMnetiQ6P6V6.
PhosphoSitePlusiQ6P6V6.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064473.

Family & Domainsi

Sequence similaritiesi

Belongs to the LU7TM family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2569. Eukaryota.
ENOG410XQAQ. LUCA.
HOVERGENiHBG056147.
InParanoidiQ6P6V6.
PhylomeDBiQ6P6V6.

Family and domain databases

InterProiIPR009637. GPR107-like.
[Graphical view]
PANTHERiPTHR21229. PTHR21229. 2 hits.
PfamiPF06814. Lung_7-TM_R. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6P6V6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVSERRGLS GESPAQCRWE YLSLLVLMLS GCSGRIHRLT LTGEKRADIQ
60 70 80 90 100
LNSFGFYTNG SLEVELSLLR LSLQETEDKF PKVGFSLSRV RSGSVRSYSS
110 120 130 140 150
RNSHECPLER NSSNFLVLFL INIKDLQVQV RKYGEQKLFI SPGLLPEAPS
160 170 180 190 200
QSGPPKPDPT GTPKDNHVIH PSPKKMSAVK EDQAKLTVPQ VSGDKALPAG
210 220 230 240 250
HRHSSDGQPQ SQPPTRGPSG KEKDLVLGLG HLNDSYNFSF HIVIGSRAEE
260 270 280 290 300
GQYSLNFHNC YNTIPGQEQP FDLTVMIREK NPEGFLSAAE IPLFKLYLIM
310 320 330 340 350
SACFLAAGIF WVSVLCKNTY SVFKIHWLMA ALAFTKSVSL LFHSINYYFI
360 370 380 390 400
NSQGHPIEGL AVMHYITHLL KGALLFITIA LIGSGWAFVK YMLSDKEKKI
410 420 430 440 450
FGIVIPLQVL ANVAYIVIES REEGASDYGL WKEILFLVDL ICCGAILFPV
460 470 480 490 500
VWSIRHLQDA SGTDGKVAMN LAKLKLFRHY YVMVICYIYF TRIIAILLRV
510 520 530 540 550
AVPFQWQWLY QLLVESSTLA FFVLTGYKFQ PAGDNPYLQL PQQEDEEDVQ
560 570
MEQVMTDSGF REGLSKVNKT ASGRELL
Length:577
Mass (Da):64,721
Last modified:July 5, 2004 - v1
Checksum:i686C90BC1F657D78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061996 mRNA. Translation: AAH61996.1.
RefSeqiNP_955431.1. NM_199399.1.
UniGeneiRn.203125.

Genome annotation databases

GeneIDi316136.
KEGGirno:316136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC061996 mRNA. Translation: AAH61996.1.
RefSeqiNP_955431.1. NM_199399.1.
UniGeneiRn.203125.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064473.

PTM databases

iPTMnetiQ6P6V6.
PhosphoSitePlusiQ6P6V6.

Proteomic databases

PaxDbiQ6P6V6.
PRIDEiQ6P6V6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi316136.
KEGGirno:316136.

Organism-specific databases

CTDi56927.
RGDi735149. Gpr108.

Phylogenomic databases

eggNOGiKOG2569. Eukaryota.
ENOG410XQAQ. LUCA.
HOVERGENiHBG056147.
InParanoidiQ6P6V6.
PhylomeDBiQ6P6V6.

Miscellaneous databases

PROiQ6P6V6.

Family and domain databases

InterProiIPR009637. GPR107-like.
[Graphical view]
PANTHERiPTHR21229. PTHR21229. 2 hits.
PfamiPF06814. Lung_7-TM_R. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGP108_RAT
AccessioniPrimary (citable) accession number: Q6P6V6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.