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Protein

Zinc transporter ZIP11

Gene

Slc39a11

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Functions as a cellular zinc transporter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport, Zinc transport

Keywords - Ligandi

Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc transporter ZIP11
Alternative name(s):
Solute carrier family 39 member 11
Zrt- and Irt-like protein 11
Short name:
ZIP-11
Gene namesi
Name:Slc39a11
Synonyms:Zip11
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1311981. Slc39a11.

Subcellular locationi

  • Cell membrane By similarity; Multi-pass membrane protein Curated
  • Nucleus By similarity
  • Cytoplasm By similarity
  • Golgi apparatus By similarity

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Transmembranei187 – 207HelicalSequence analysisAdd BLAST21
Transmembranei256 – 278HelicalSequence analysisAdd BLAST23
Transmembranei283 – 300HelicalSequence analysisAdd BLAST18
Transmembranei315 – 335HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003084121 – 335Zinc transporter ZIP11Add BLAST335

Proteomic databases

PaxDbiQ6P6S2.
PRIDEiQ6P6S2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000031213.
GenevisibleiQ6P6S2. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000039028.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2474. Eukaryota.
COG0428. LUCA.
GeneTreeiENSGT00390000006167.
HOGENOMiHOG000202721.
HOVERGENiHBG108448.
InParanoidiQ6P6S2.
KOiK14717.
OMAiMIFVVIE.
OrthoDBiEOG091G0LUY.
PhylomeDBiQ6P6S2.

Family and domain databases

InterProiIPR003689. ZIP.
[Graphical view]
PfamiPF02535. Zip. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P6S2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQGYSSVSQ ALLGTFFTWA MTAAGAALVF IFSSGQRRIL DGSLGFAAGV
60 70 80 90 100
MLAASYWSLL APAVEMATSS GGFGAFAFFP VAVGFTLGAA FVYLADLLMP
110 120 130 140 150
HLGAGEDPQT ALALNLDPAL VKKSDLKDPA SLLFPERELS IRIDKRENGE
160 170 180 190 200
VYQRKKLAAT DFPEGAAPSG PVHGNSGQPG VSSWRRIALL ILAITIHNIP
210 220 230 240 250
EGLAVGVGFG AVEKTASATF ESARNLAIGI GIQNFPEGLA VSLPLRGAGF
260 270 280 290 300
STWKAFWYGQ LSGMVEPLAG VFGAFAVVLA EPVLPYALAF AAGAMVYVVM
310 320 330
DDIIPEAQIS GNGKLASWAS ILGFVVMMSL DVGLG
Length:335
Mass (Da):34,868
Last modified:July 5, 2004 - v1
Checksum:i641975960723C277
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC062054 mRNA. Translation: AAH62054.1.
RefSeqiNP_001013060.1. NM_001013042.1.
UniGeneiRn.205133.

Genome annotation databases

EnsembliENSRNOT00000042156; ENSRNOP00000039028; ENSRNOG00000031213.
GeneIDi287796.
KEGGirno:287796.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC062054 mRNA. Translation: AAH62054.1.
RefSeqiNP_001013060.1. NM_001013042.1.
UniGeneiRn.205133.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000039028.

Proteomic databases

PaxDbiQ6P6S2.
PRIDEiQ6P6S2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000042156; ENSRNOP00000039028; ENSRNOG00000031213.
GeneIDi287796.
KEGGirno:287796.

Organism-specific databases

CTDi201266.
RGDi1311981. Slc39a11.

Phylogenomic databases

eggNOGiKOG2474. Eukaryota.
COG0428. LUCA.
GeneTreeiENSGT00390000006167.
HOGENOMiHOG000202721.
HOVERGENiHBG108448.
InParanoidiQ6P6S2.
KOiK14717.
OMAiMIFVVIE.
OrthoDBiEOG091G0LUY.
PhylomeDBiQ6P6S2.

Miscellaneous databases

PROiQ6P6S2.

Gene expression databases

BgeeiENSRNOG00000031213.
GenevisibleiQ6P6S2. RN.

Family and domain databases

InterProiIPR003689. ZIP.
[Graphical view]
PfamiPF02535. Zip. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS39AB_RAT
AccessioniPrimary (citable) accession number: Q6P6S2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.