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Protein

Synaptosomal-associated protein 47

Gene

Snap47

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in intracellular membrane fusion.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptosomal-associated protein 47
Short name:
SNAP-47
Alternative name(s):
Synaptosomal-associated 47 kDa protein
Gene namesi
Name:Snap47
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi735194. Snap47.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 419419Synaptosomal-associated protein 47PRO_0000307153Add
BLAST

Proteomic databases

PaxDbiQ6P6S0.
PRIDEiQ6P6S0.

PTM databases

iPTMnetiQ6P6S0.
PhosphoSiteiQ6P6S0.

Interactioni

Subunit structurei

Associates with the BLOC-1 complex. Interacts with BLOC1S6. Forms a complex containing SNAP47, VAMP2 and STX1A (By similarity).By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000029215.

Structurei

3D structure databases

ProteinModelPortaliQ6P6S0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini109 – 17163t-SNARE coiled-coil homology 1PROSITE-ProRule annotationAdd
BLAST
Domaini356 – 41863t-SNARE coiled-coil homology 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the SVAP1 family.Curated
Contains 2 t-SNARE coiled-coil homology domains.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG3065. Eukaryota.
ENOG410Y3Y0. LUCA.
GeneTreeiENSGT00390000000182.
HOGENOMiHOG000056669.
HOVERGENiHBG057915.
InParanoidiQ6P6S0.
KOiK18212.
OMAiVLEHFWR.
OrthoDBiEOG70ZZNG.
PhylomeDBiQ6P6S0.
TreeFamiTF331066.

Family and domain databases

InterProiIPR000727. T_SNARE_dom.
[Graphical view]
PROSITEiPS50192. T_SNARE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6P6S0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDVRVHTW PCSYYLDLEK QWLPGKLTLT PRSLKFSVDK AEEVLVGLPL
60 70 80 90 100
SSITEIRKET SLFIFSAITV LEKGQAKHWF SSLRPSRNVV FNIIEHFWRE
110 120 130 140 150
LLLSQPGTAA NPTSPMTRGQ ELMGLMASSQ RRMEDTAKVL HHQGEQLDSV
160 170 180 190 200
MRGLEKMESD LDVADRLLTE LETPSWWPFS AKFWKTPVEA KPRDSVSVAP
210 220 230 240 250
CEPFGKEGVV IRVPAVVSQR TESHSKPGKL TVLVSGLEIH DSSSLLLHRF
260 270 280 290 300
EKEDVDDIKV HSPYEVSIRQ RFIGKPDVAY RLISAKMPEV IPILEVQFSK
310 320 330 340 350
KIELLEDALV LRSRGRASPA EGGCSIRHAA SRLMGCTTHQ ELPTGGQEGQ
360 370 380 390 400
QSQLQKDWPL LSEGEAQELT QILSKLKGLA LDTEAELERQ DAALDGITVA
410
VDRATLTVDK HNRRMRKLL
Length:419
Mass (Da):47,042
Last modified:July 5, 2004 - v1
Checksum:i4B7D9E4E9A448D0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC062056 mRNA. Translation: AAH62056.1.
RefSeqiNP_955421.1. NM_199389.1.
XP_006246550.1. XM_006246488.2.
UniGeneiRn.143911.

Genome annotation databases

EnsembliENSRNOT00000028948; ENSRNOP00000029215; ENSRNOG00000022472.
GeneIDi303183.
KEGGirno:303183.
UCSCiRGD:735194. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC062056 mRNA. Translation: AAH62056.1.
RefSeqiNP_955421.1. NM_199389.1.
XP_006246550.1. XM_006246488.2.
UniGeneiRn.143911.

3D structure databases

ProteinModelPortaliQ6P6S0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000029215.

PTM databases

iPTMnetiQ6P6S0.
PhosphoSiteiQ6P6S0.

Proteomic databases

PaxDbiQ6P6S0.
PRIDEiQ6P6S0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028948; ENSRNOP00000029215; ENSRNOG00000022472.
GeneIDi303183.
KEGGirno:303183.
UCSCiRGD:735194. rat.

Organism-specific databases

CTDi116841.
RGDi735194. Snap47.

Phylogenomic databases

eggNOGiKOG3065. Eukaryota.
ENOG410Y3Y0. LUCA.
GeneTreeiENSGT00390000000182.
HOGENOMiHOG000056669.
HOVERGENiHBG057915.
InParanoidiQ6P6S0.
KOiK18212.
OMAiVLEHFWR.
OrthoDBiEOG70ZZNG.
PhylomeDBiQ6P6S0.
TreeFamiTF331066.

Miscellaneous databases

PROiQ6P6S0.

Family and domain databases

InterProiIPR000727. T_SNARE_dom.
[Graphical view]
PROSITEiPS50192. T_SNARE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.

Entry informationi

Entry nameiSNP47_RAT
AccessioniPrimary (citable) accession number: Q6P6S0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: June 8, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.