Q6P6S0 (SNP47_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Synaptosomal-associated protein 47
Short name=SNAP-47

Alternative name(s):
Synaptosomal-associated 47 kDa protein

Gene names

Name:

Snap47

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May play a role in intracellular membrane fusion By similarity.
Subunit structure	Forms a complex containing SNAP47, VAMP2 and STX1A By similarity.
Subcellular location	Endomembrane system By similarity. Cytoplasm › perinuclear region By similarity. Note: Appears to be exclusively membrane-bound By similarity.
Sequence similarities	Belongs to the SVAP1 family. Contains 2 t-SNARE coiled-coil homology domains.

Ontologies

Keywords
Cellular component	Cytoplasm Membrane
Domain	Coiled coil Repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	endomembrane system Inferred from electronic annotation. Source: UniProtKB-SubCell membrane Inferred from electronic annotation. Source: UniProtKB-KW perinuclear region of cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 419	419	Synaptosomal-associated protein 47		PRO_0000307153
Regions
	Domain	109 – 171	63	t-SNARE coiled-coil homology 1
	Domain	356 – 418	63	t-SNARE coiled-coil homology 2

Sequences

	Sequence		Length	Mass (Da)
	Q6P6S0 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4B7D9E4E9A448D0F	FASTA	419	47,042
	10 20 30 40 50 60 MSSDVRVHTW PCSYYLDLEK QWLPGKLTLT PRSLKFSVDK AEEVLVGLPL SSITEIRKET 70 80 90 100 110 120 SLFIFSAITV LEKGQAKHWF SSLRPSRNVV FNIIEHFWRE LLLSQPGTAA NPTSPMTRGQ 130 140 150 160 170 180 ELMGLMASSQ RRMEDTAKVL HHQGEQLDSV MRGLEKMESD LDVADRLLTE LETPSWWPFS 190 200 210 220 230 240 AKFWKTPVEA KPRDSVSVAP CEPFGKEGVV IRVPAVVSQR TESHSKPGKL TVLVSGLEIH 250 260 270 280 290 300 DSSSLLLHRF EKEDVDDIKV HSPYEVSIRQ RFIGKPDVAY RLISAKMPEV IPILEVQFSK 310 320 330 340 350 360 KIELLEDALV LRSRGRASPA EGGCSIRHAA SRLMGCTTHQ ELPTGGQEGQ QSQLQKDWPL 370 380 390 400 410 LSEGEAQELT QILSKLKGLA LDTEAELERQ DAALDGITVA VDRATLTVDK HNRRMRKLL

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Prostate.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC062056 mRNA. Translation: AAH62056.1.
IPI	IPI00369583.
RefSeq	NP_955421.1. NM_199389.1.
UniGene	Rn.143911.
3D structure databases
ProteinModelPortal	Q6P6S0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6P6S0.
PTM databases
PhosphoSite	Q6P6S0.
Proteomic databases
PRIDE	Q6P6S0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000028948; ENSRNOP00000029215; ENSRNOG00000022472.
GeneID	303183.
KEGG	rno:303183.
NMPDR	fig|10116.3.peg.5136.
UCSC	NM_199389. rat.
Organism-specific databases
CTD	116841.
RGD	735194. Snap47.
Phylogenomic databases
eggNOG	roNOG15493.
GeneTree	ENSGT00390000000182.
HOVERGEN	HBG057915.
InParanoid	Q6P6S0.
OMA	LEHFWRE.
OrthoDB	EOG4H72C0.
PhylomeDB	Q6P6S0.
Gene expression databases
Genevestigator	Q6P6S0.
Family and domain databases
InterPro	IPR000727. T_SNARE_dom. [Graphical view]
KO	K08509.
PROSITE	PS50192. T_SNARE. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	650811.

Entry information

Entry name

SNP47_RAT

Accession

Primary (citable) accession number: Q6P6S0

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	July 5, 2004
Last modified:	November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program