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Protein

Synaptosomal-associated protein 47

Gene

Snap47

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in intracellular membrane fusion.By similarity

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptosomal-associated protein 47
Short name:
SNAP-47
Alternative name(s):
Synaptosomal-associated 47 kDa protein
Gene namesi
Name:Snap47
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi735194 Snap47

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003071531 – 419Synaptosomal-associated protein 47Add BLAST419

Proteomic databases

PaxDbiQ6P6S0
PRIDEiQ6P6S0

PTM databases

iPTMnetiQ6P6S0
PhosphoSitePlusiQ6P6S0

Expressioni

Gene expression databases

BgeeiENSRNOG00000022472

Interactioni

Subunit structurei

Associates with the BLOC-1 complex. Interacts with BLOC1S6. Forms a complex containing SNAP47, VAMP2 and STX1A (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

CORUMiQ6P6S0
STRINGi10116.ENSRNOP00000029215

Structurei

3D structure databases

ProteinModelPortaliQ6P6S0
SMRiQ6P6S0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini109 – 171t-SNARE coiled-coil homology 1PROSITE-ProRule annotationAdd BLAST63
Domaini356 – 418t-SNARE coiled-coil homology 2PROSITE-ProRule annotationAdd BLAST63

Sequence similaritiesi

Belongs to the SVAP1 family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG3065 Eukaryota
ENOG410Y3Y0 LUCA
GeneTreeiENSGT00390000000182
HOGENOMiHOG000056669
HOVERGENiHBG057915
InParanoidiQ6P6S0
KOiK18212
OMAiQGEQFDN
OrthoDBiEOG091G0TY9
PhylomeDBiQ6P6S0
TreeFamiTF331066

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011993 PH-like_dom_sf
IPR000727 T_SNARE_dom
PROSITEiView protein in PROSITE
PS50192 T_SNARE, 2 hits

Sequencei

Sequence statusi: Complete.

Q6P6S0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDVRVHTW PCSYYLDLEK QWLPGKLTLT PRSLKFSVDK AEEVLVGLPL
60 70 80 90 100
SSITEIRKET SLFIFSAITV LEKGQAKHWF SSLRPSRNVV FNIIEHFWRE
110 120 130 140 150
LLLSQPGTAA NPTSPMTRGQ ELMGLMASSQ RRMEDTAKVL HHQGEQLDSV
160 170 180 190 200
MRGLEKMESD LDVADRLLTE LETPSWWPFS AKFWKTPVEA KPRDSVSVAP
210 220 230 240 250
CEPFGKEGVV IRVPAVVSQR TESHSKPGKL TVLVSGLEIH DSSSLLLHRF
260 270 280 290 300
EKEDVDDIKV HSPYEVSIRQ RFIGKPDVAY RLISAKMPEV IPILEVQFSK
310 320 330 340 350
KIELLEDALV LRSRGRASPA EGGCSIRHAA SRLMGCTTHQ ELPTGGQEGQ
360 370 380 390 400
QSQLQKDWPL LSEGEAQELT QILSKLKGLA LDTEAELERQ DAALDGITVA
410
VDRATLTVDK HNRRMRKLL
Length:419
Mass (Da):47,042
Last modified:July 5, 2004 - v1
Checksum:i4B7D9E4E9A448D0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC062056 mRNA Translation: AAH62056.1
RefSeqiNP_955421.1, NM_199389.1
XP_006246550.1, XM_006246488.3
UniGeneiRn.143911

Genome annotation databases

EnsembliENSRNOT00000028948; ENSRNOP00000029215; ENSRNOG00000022472
GeneIDi303183
KEGGirno:303183
UCSCiRGD:735194 rat

Similar proteinsi

Entry informationi

Entry nameiSNP47_RAT
AccessioniPrimary (citable) accession number: Q6P6S0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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