Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6P5W5

- S39A4_HUMAN

UniProt

Q6P5W5 - S39A4_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Zinc transporter ZIP4

Gene

SLC39A4

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability By similarity.By similarity

GO - Molecular functioni

  1. zinc ion transmembrane transporter activity Source: Ensembl

GO - Biological processi

  1. cellular response to zinc ion starvation Source: Ensembl
  2. cellular zinc ion homeostasis Source: Ensembl
  3. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport, Zinc transport

Keywords - Ligandi

Zinc

Enzyme and pathway databases

ReactomeiREACT_20603. Zinc influx into cells by the SLC39 gene family.

Protein family/group databases

TCDBi2.A.5.4.1. the zinc (zn(2+))-iron (fe(2+)) permease (zip) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc transporter ZIP4
Alternative name(s):
Solute carrier family 39 member 4
Zrt- and Irt-like protein 4
Short name:
ZIP-4
Gene namesi
Name:SLC39A4
Synonyms:ZIP4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 8

Organism-specific databases

HGNCiHGNC:17129. SLC39A4.

Subcellular locationi

Cell membrane 1 Publication; Multi-pass membrane protein 1 Publication. Recycling endosome membrane 1 Publication; Multi-pass membrane protein 1 Publication
Note: Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. cytoplasmic membrane-bounded vesicle Source: UniProtKB
  3. endosome Source: UniProtKB-KW
  4. extracellular vesicular exosome Source: UniProt
  5. integral component of membrane Source: UniProtKB-KW
  6. plasma membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endosome, Membrane

Pathology & Biotechi

Involvement in diseasei

Acrodermatitis enteropathica, zinc-deficiency type (AEZ) [MIM:201100]: A rare autosomal recessive disease caused by the inability to absorb sufficient zinc. The clinical features are growth retardation, immune-system dysfunction, alopecia, severe dermatitis, diarrhea and occasionally mental disorders.4 Publications
Note: The disease is caused by mutations affecting the gene represented in this entry.
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti84 – 841P → L in AEZ; unknown pathological significance. 1 Publication
VAR_023628
Natural varianti95 – 951R → C in AEZ. 1 Publication
VAR_023629
Natural varianti106 – 1061N → K in AEZ. 1 Publication
VAR_023630
Natural varianti200 – 2001P → L in AEZ. 1 Publication
VAR_023632
Natural varianti251 – 2511R → W in AEZ; unknown pathological significance. 2 Publications
Corresponds to variant rs2977838 [ dbSNP | Ensembl ].
VAR_023633
Natural varianti303 – 3031Q → H in AEZ. 1 Publication
VAR_023634
Natural varianti309 – 3091C → Y in AEZ; unknown pathological significance. 2 Publications
VAR_023635
Natural varianti330 – 3301G → D in AEZ. 1 Publication
VAR_023636
Natural varianti372 – 3721L → P in AEZ. 1 Publication
VAR_023638
Natural varianti374 – 3741G → R in AEZ. 1 Publication
VAR_023639
Natural varianti410 – 4101L → P in AEZ; unknown pathological significance. 1 Publication
VAR_023640
Natural varianti526 – 5261G → R in AEZ. 1 Publication
VAR_023641
Natural varianti630 – 6301G → R in AEZ. 1 Publication
VAR_023642

Keywords - Diseasei

Disease mutation

Organism-specific databases

MIMi201100. phenotype.
Orphaneti37. Acrodermatitis enteropathica.
PharmGKBiPA38204.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 647625Zinc transporter ZIP4PRO_0000042620Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi261 – 2611N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ6P5W5.
PaxDbiQ6P5W5.
PRIDEiQ6P5W5.

PTM databases

PhosphoSiteiQ6P5W5.

Expressioni

Tissue specificityi

Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.2 Publications

Gene expression databases

BgeeiQ6P5W5.
CleanExiHS_SLC39A4.
ExpressionAtlasiQ6P5W5. baseline and differential.
GenevestigatoriQ6P5W5.

Organism-specific databases

HPAiHPA031507.

Interactioni

Protein-protein interaction databases

BioGridi120769. 96 interactions.
STRINGi9606.ENSP00000372700.

Structurei

3D structure databases

ProteinModelPortaliQ6P5W5.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini23 – 327305ExtracellularSequence AnalysisAdd
BLAST
Topological domaini349 – 35911CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini381 – 40222ExtracellularSequence AnalysisAdd
BLAST
Topological domaini424 – 558135CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini580 – 5867ExtracellularSequence Analysis
Topological domaini608 – 61710CytoplasmicSequence Analysis
Topological domaini639 – 6479ExtracellularSequence Analysis

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei328 – 34821Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei360 – 38021Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei403 – 42321Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei559 – 57921Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei587 – 60721Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei618 – 63821Helical; Name=6Sequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0428.
HOGENOMiHOG000293181.
HOVERGENiHBG062532.
InParanoidiQ6P5W5.
KOiK14710.
PhylomeDBiQ6P5W5.
TreeFamiTF318470.

Family and domain databases

InterProiIPR003689. ZIP.
[Graphical view]
PfamiPF02535. Zip. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q6P5W5-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASLVSLELG LLLAVLVVTA TASPPAGLLS LLTSGQGALD QEALGGLLNT
60 70 80 90 100
LADRVHCANG PCGKCLSVED ALGLGEPEGS GLPPGPVLEA RYVARLSAAA
110 120 130 140 150
VLYLSNPEGT CEDARAGLWA SHADHLLALL ESPKALTPGL SWLLQRMQAR
160 170 180 190 200
AAGQTPKTAC VDIPQLLEEA VGAGAPGSAG GVLAALLDHV RSGSCFHALP
210 220 230 240 250
SPQYFVDFVF QQHSSEVPMT LAELSALMQR LGVGREAHSD HSHRHRGASS
260 270 280 290 300
RDPVPLISSS NSSSVWDTVC LSARDVMAAY GLSEQAGVTP EAWAQLSPAL
310 320 330 340 350
LQQQLSGACT SQSRPPVQDQ LSQSERYLYG SLATLLICLC AVFGLLLLTC
360 370 380 390 400
TGCRGVTHYI LQTFLSLAVG ALTGDAVLHL TPKVLGLHTH SEEGLSPQPT
410 420 430 440 450
WRLLAMLAGL YAFFLFENLF NLLLPRDPED LEDGPCGHSS HSHGGHSHGV
460 470 480 490 500
SLQLAPSELR QPKPPHEGSR ADLVAEESPE LLNPEPRRLS PELRLLPYMI
510 520 530 540 550
TLGDAVHNFA DGLAVGAAFA SSWKTGLATS LAVFCHELPH ELGDFAALLH
560 570 580 590 600
AGLSVRQALL LNLASALTAF AGLYVALAVG VSEESEAWIL AVATGLFLYV
610 620 630 640
ALCDMLPAML KVRDPRPWLL FLLHNVGLLG GWTVLLLLSL YEDDITF
Length:647
Mass (Da):68,392
Last modified:May 18, 2010 - v3
Checksum:i1B482200EB78F881
GO
Isoform 2 (identifier: Q6P5W5-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-25: Missing.
     26-64: AGLLSLLTSG...VHCANGPCGK → MVDVVGLERE...APLLTCLCPQ

Show »
Length:622
Mass (Da):66,162
Checksum:iAEC20AD677CB3D62
GO

Sequence cautioni

The sequence BAA91091.1 differs from that shown. Reason: Frameshift at positions 573, 598 and 618.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti22 – 221A → E.
Corresponds to variant rs2280839 [ dbSNP | Ensembl ].
VAR_060487
Natural varianti58 – 581A → T.3 Publications
Corresponds to variant rs2280838 [ dbSNP | Ensembl ].
VAR_023627
Natural varianti84 – 841P → L in AEZ; unknown pathological significance. 1 Publication
VAR_023628
Natural varianti95 – 951R → C in AEZ. 1 Publication
VAR_023629
Natural varianti106 – 1061N → K in AEZ. 1 Publication
VAR_023630
Natural varianti114 – 1141A → T.3 Publications
Corresponds to variant rs17855765 [ dbSNP | Ensembl ].
VAR_023631
Natural varianti158 – 1581T → M.
Corresponds to variant rs1871533 [ dbSNP | Ensembl ].
VAR_057481
Natural varianti200 – 2001P → L in AEZ. 1 Publication
VAR_023632
Natural varianti251 – 2511R → W in AEZ; unknown pathological significance. 2 Publications
Corresponds to variant rs2977838 [ dbSNP | Ensembl ].
VAR_023633
Natural varianti284 – 2841E → K.
Corresponds to variant rs7823979 [ dbSNP | Ensembl ].
VAR_057482
Natural varianti303 – 3031Q → H in AEZ. 1 Publication
VAR_023634
Natural varianti309 – 3091C → Y in AEZ; unknown pathological significance. 2 Publications
VAR_023635
Natural varianti330 – 3301G → D in AEZ. 1 Publication
VAR_023636
Natural varianti357 – 3571T → A.2 Publications
Corresponds to variant rs2272662 [ dbSNP | Ensembl ].
VAR_023637
Natural varianti372 – 3721L → P in AEZ. 1 Publication
VAR_023638
Natural varianti372 – 3721L → V.
Corresponds to variant rs1871534 [ dbSNP | Ensembl ].
VAR_057483
Natural varianti374 – 3741G → R in AEZ. 1 Publication
VAR_023639
Natural varianti378 – 3781L → V.
Corresponds to variant rs4483198 [ dbSNP | Ensembl ].
VAR_060488
Natural varianti410 – 4101L → P in AEZ; unknown pathological significance. 1 Publication
VAR_023640
Natural varianti526 – 5261G → R in AEZ. 1 Publication
VAR_023641
Natural varianti630 – 6301G → R in AEZ. 1 Publication
VAR_023642

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 2525Missing in isoform 2. 2 PublicationsVSP_015911Add
BLAST
Alternative sequencei26 – 6439AGLLS…GPCGK → MVDVVGLERETGPRGSPWPG LPLPSLVGPAPLLTCLCPQ in isoform 2. 2 PublicationsVSP_015912Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK000334 mRNA. Translation: BAA91091.1. Frameshift.
AK025537 mRNA. Translation: BAB15164.1.
AF205589 Genomic DNA. No translation available.
BC001688 mRNA. Translation: AAH01688.2.
BC062625 mRNA. Translation: AAH62625.1.
CCDSiCCDS43782.1. [Q6P5W5-2]
CCDS6424.1. [Q6P5W5-1]
RefSeqiNP_060237.2. NM_017767.2. [Q6P5W5-2]
NP_570901.2. NM_130849.3. [Q6P5W5-1]
UniGeneiHs.521934.

Genome annotation databases

EnsembliENST00000301305; ENSP00000301305; ENSG00000147804.
GeneIDi55630.
KEGGihsa:55630.
UCSCiuc003zco.3. human. [Q6P5W5-1]
uc003zcp.3. human. [Q6P5W5-2]

Polymorphism databases

DMDMi296452970.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK000334 mRNA. Translation: BAA91091.1 . Frameshift.
AK025537 mRNA. Translation: BAB15164.1 .
AF205589 Genomic DNA. No translation available.
BC001688 mRNA. Translation: AAH01688.2 .
BC062625 mRNA. Translation: AAH62625.1 .
CCDSi CCDS43782.1. [Q6P5W5-2 ]
CCDS6424.1. [Q6P5W5-1 ]
RefSeqi NP_060237.2. NM_017767.2. [Q6P5W5-2 ]
NP_570901.2. NM_130849.3. [Q6P5W5-1 ]
UniGenei Hs.521934.

3D structure databases

ProteinModelPortali Q6P5W5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 120769. 96 interactions.
STRINGi 9606.ENSP00000372700.

Protein family/group databases

TCDBi 2.A.5.4.1. the zinc (zn(2+))-iron (fe(2+)) permease (zip) family.

PTM databases

PhosphoSitei Q6P5W5.

Polymorphism databases

DMDMi 296452970.

Proteomic databases

MaxQBi Q6P5W5.
PaxDbi Q6P5W5.
PRIDEi Q6P5W5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000301305 ; ENSP00000301305 ; ENSG00000147804 .
GeneIDi 55630.
KEGGi hsa:55630.
UCSCi uc003zco.3. human. [Q6P5W5-1 ]
uc003zcp.3. human. [Q6P5W5-2 ]

Organism-specific databases

CTDi 55630.
GeneCardsi GC08M145637.
H-InvDB HIX0007856.
HGNCi HGNC:17129. SLC39A4.
HPAi HPA031507.
MIMi 201100. phenotype.
607059. gene.
neXtProti NX_Q6P5W5.
Orphaneti 37. Acrodermatitis enteropathica.
PharmGKBi PA38204.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0428.
HOGENOMi HOG000293181.
HOVERGENi HBG062532.
InParanoidi Q6P5W5.
KOi K14710.
PhylomeDBi Q6P5W5.
TreeFami TF318470.

Enzyme and pathway databases

Reactomei REACT_20603. Zinc influx into cells by the SLC39 gene family.

Miscellaneous databases

GenomeRNAii 55630.
NextBioi 60265.
PROi Q6P5W5.
SOURCEi Search...

Gene expression databases

Bgeei Q6P5W5.
CleanExi HS_SLC39A4.
ExpressionAtlasi Q6P5W5. baseline and differential.
Genevestigatori Q6P5W5.

Family and domain databases

InterProi IPR003689. ZIP.
[Graphical view ]
Pfami PF02535. Zip. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of SLC39A4, a gene involved in acrodermatitis enteropathica."
    Kuery S., Dreno B., Bezieau S., Giraudet S., Kharfi M., Kamoun R., Moisan J.-P.
    Nat. Genet. 31:239-240(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY, VARIANTS AEZ LEU-200; ARG-374 AND ARG-526.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANTS THR-58; THR-114; AEZ TYR-309 AND ALA-357.
  3. "DNA sequence and analysis of human chromosome 8."
    Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
    , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
    Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT TRP-251.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS THR-58 AND THR-114.
    Tissue: Lung and Ovary.
  5. "A novel member of a zinc transporter family is defective in acrodermatitis enteropathica."
    Wang K., Zhou B., Kuo Y.-M., Zemansky J., Gitschier J.
    Am. J. Hum. Genet. 71:66-73(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY, VARIANTS THR-58; THR-114 AND ALA-357, VARIANTS AEZ LEU-84; LYS-106; TRP-251; TYR-309; ASP-330; PRO-372; PRO-410 AND ARG-630.
  6. "Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane."
    Kim B.-E., Wang F., Dufner-Beattie J., Andrews G.K., Eide D.J., Petris M.J.
    J. Biol. Chem. 279:4523-4530(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  7. "Novel SLC39A4 mutations in acrodermatitis enteropathica."
    Nakano A., Nakano H., Nomura K., Toyomaki Y., Hanada K.
    J. Invest. Dermatol. 120:963-966(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS AEZ CYS-95 AND HIS-303.

Entry informationi

Entry nameiS39A4_HUMAN
AccessioniPrimary (citable) accession number: Q6P5W5
Secondary accession number(s): Q7L5S5, Q9H6T8, Q9NXC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: May 18, 2010
Last modified: October 29, 2014
This is version 96 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3