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Protein
Submitted name:

AQP7 protein

Gene

AQP7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AQP7 proteinImported
Submitted name:
Aquaporin 7, isoform CRA_bImported
Submitted name:
Aquaporin-7Imported
Gene namesi
Name:AQP7Imported
ORF Names:hCG_2011318Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:640. AQP7.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 28HelicalSequence analysisAdd BLAST22
Transmembranei57 – 77HelicalSequence analysisAdd BLAST21
Transmembranei89 – 106HelicalSequence analysisAdd BLAST18
Transmembranei146 – 168HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165269.

Expressioni

Gene expression databases

BgeeiENSG00000165269.
ExpressionAtlasiQ6P5T0. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ6P5T0. 1 interactor.

Family & Domainsi

Sequence similaritiesi

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00510000046311.
HOGENOMiHOG000288287.
HOVERGENiHBG106057.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiView protein in InterPro
IPR023271. Aquaporin-like.
IPR015686. Aquaporin_7.
IPR000425. MIP.
PANTHERiPTHR43829:SF4. PTHR43829:SF4. 1 hit.
PfamiView protein in Pfam
PF00230. MIP. 1 hit.
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6P5T0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLNKKYGSY LGVNLGFGFG VTMGVHVAGR ISGAHMNAAV TFANCALGRV
60 70 80 90 100
PWRKFPVYVL GQFLGSFLAA ATIYSLFYTA ILHFSGGQLM VTGPVATAGI
110 120 130 140 150
FATYLPDHMT LWRGFLNEAW LTGMLQLCLF AITDQENNPA LPGTEALVIG
160 170 180 190 200
ILVVIIGVSL GMNTGYAINP SRDLPPRIFT FIAGWGKQVF RWHHLPGLHW
210
LHHPTGAPEI GGFCGV
Length:216
Mass (Da):23,334
Last modified:July 5, 2004 - v1
Checksum:iBB2E487C1677749A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356218 Genomic DNA. No translation available.
BC062701 mRNA. Translation: AAH62701.1.
CH471071 Genomic DNA. Translation: EAW58506.1.
RefSeqiNP_001305085.1. NM_001318156.1.
UniGeneiHs.455323.

Genome annotation databases

EnsembliENST00000377425; ENSP00000396111; ENSG00000165269.
GeneIDi364.
UCSCiuc003zsu.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356218 Genomic DNA. No translation available.
BC062701 mRNA. Translation: AAH62701.1.
CH471071 Genomic DNA. Translation: EAW58506.1.
RefSeqiNP_001305085.1. NM_001318156.1.
UniGeneiHs.455323.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6P5T0. 1 interactor.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000377425; ENSP00000396111; ENSG00000165269.
GeneIDi364.
UCSCiuc003zsu.2. human.

Organism-specific databases

CTDi364.
HGNCiHGNC:640. AQP7.
OpenTargetsiENSG00000165269.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00510000046311.
HOGENOMiHOG000288287.
HOVERGENiHBG106057.

Miscellaneous databases

GenomeRNAii364.

Gene expression databases

BgeeiENSG00000165269.
ExpressionAtlasiQ6P5T0. baseline and differential.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiView protein in InterPro
IPR023271. Aquaporin-like.
IPR015686. Aquaporin_7.
IPR000425. MIP.
PANTHERiPTHR43829:SF4. PTHR43829:SF4. 1 hit.
PfamiView protein in Pfam
PF00230. MIP. 1 hit.
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6P5T0_HUMAN
AccessioniPrimary (citable) accession number: Q6P5T0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 15, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.